Cash flow generation remains volatile, evidenced by a $49.6 million working capital outflow in 2026Q1 compared to a $74.0 million inflow in 2025Q4.
| Cash from Operations | 341.97M | 348.2M | 219.82M | 219.39M | 144.47M | 98.56M | -2.98M | -75.44M | -38.8M |
| Operating CF Margin % | - | 40.09% | 30.76% | 37.69% | 32.99% | 32.27% | -1.87% | -1258.32% | - |
| Operating CF Growth % | 189% | 58.4% | 0.2% | 51.86% | 46.58% | 3401.74% | 96.04% | -94.43% | - |
| Net Income | 145.62M | 158.69M | 145.49M | 128.85M | 181.47M | 34.6M | -36.94M | -151.98M | -39.9M |
| Depreciation & Amortization | 25.5M | 25.34M | 24.11M | 24.36M | 25.05M | 21.08M | 10.24M | 3.8M | 184K |
| Stock-Based Compensation | 32.45M | 44.9M | 42.6M | 31.7M | 26.91M | 16.11M | 4.69M | 9.91M | 1.08M |
| Deferred Taxes | 4.33M | 0 | -29.3M | -13.42M | 0 | 0 | 25.75M | 0 | 0 |
| Other Non-Cash Items | 64.08M | 27.46M | 44.23M | 12.85M | -82.06M | 24.59M | 4.91M | 59.44M | 2.06M |
| Working Capital Changes | 70.01M | 91.82M | -7.32M | 35.03M | -6.89M | 2.19M | -11.63M | 3.39M | -164K |
| Change in Receivables | -2.25M | -13.75M | -8.89M | -19.4M | -19.9M | -12.67M | -17.92M | -4.25M | 0 |
| Change in Inventory | 1.1M | 1.84M | -1.83M | -1.07M | 135K | -609K | -2.73M | -1.09M | 0 |
| Change in Payables | 13.1M | 3.95M | -5.38M | 8.95M | 0 | 0 | -3.8M | 0 | -610K |
| Cash from Investing | -225.66M | -39.65M | -67.48M | -46.44M | -141.83M | -100.3M | -2M | -127.15M | -1.34M |
| Capital Expenditures | -19.43M | -19.56M | -1.15M | -312K | -172K | -298K | -2M | -149K | -1.34M |
| CapEx % of Revenue | 2.16% | 2.25% | 0.16% | 0.05% | 0.04% | 0.1% | 1.25% | 2.49% | - |
| Acquisitions | 0 | 0 | -33.07M | -36.97M | 0 | 0 | -2M | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | -51.72M | -15M | -26.5M | 0 | -141.66M | -100M | 2M | -127M | 0 |
| Cash from Financing | -15.91M | -9.05M | -11M | -105.55M | 6.84M | 7.42M | 209.16M | 143.77M | 21.61M |
| Debt Issued (Net) | -17.5M | -16.25M | -15M | -1.25M | -2M | -500K | 79.42M | 100M | 0 |
| Equity Issued (Net) | 5.85M | 10.21M | 6.5M | -100.51M | 0 | 0 | -184K | 0 | 21.8M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | -100M | 0 | 0 | -167K | 0 | -3.2M |
| Other Financing | -4.26M | -3M | -2.5M | -3.79M | 8.84M | 7.92M | 129.93M | 43.77M | -185K |
| Net Change in Cash | 100.4M | 299.5M | 141.34M | 67.4M | 9.47M | 5.68M | 204.17M | -58.82M | -18.53M |
| Free Cash Flow | 341.79M | 347.89M | 218.67M | 219.07M | 144.29M | 98.26M | -4.99M | -75.58M | -40.14M |
| FCF Margin % | 38.01% | 40.06% | 30.59% | 37.64% | 32.95% | 32.17% | -3.12% | -1260.8% | - |
| FCF Growth % | 54.38% | 59.09% | -0.19% | 51.83% | 46.85% | 2070.3% | 93.4% | -88.3% | - |
| FCF per Share | 5.82 | 5.94 | 3.78 | 3.63 | 2.36 | 1.66 | -0.09 | -1.19 | -0.82 |
| FCF Conversion (FCF/Net Income) | 2.35x | 2.19x | 1.51x | 1.70x | 0.80x | 2.85x | 0.08x | 0.50x | 0.97x |
| Interest Paid | 6.97M | 0 | 17.32M | 20.05M | 16.36M | 19.83M | 0 | 4.23M | 0 |
| Taxes Paid | 35.43M | 0 | 79.64M | 48.23M | 0 | 0 | 0 | 0 | 0 |
Single-product regulatory dependency
As reported in financial statements, Harmony Biosciences exhibits significant volatility in cash conversion, with the OCF/NI ratio swinging from a high of 5.61 in 2025Q4 to a low of 0.75 in 2025Q1, indicating that GAAP net income is frequently decoupled from actual cash generation.
The wide variance in the OCF/NI ratio suggests that reported earnings are heavily influenced by non-cash items and timing differences in working capital. Investors should monitor whether this divergence is a structural feature of the company's revenue recognition or merely a reflection of lumpy milestone payments and inventory adjustments.
Based on recent SEC filings, the company's FCF margin has demonstrated extreme instability, ranging from 12.9% in 2026Q1 to 51.7% in 2025Q4, which complicates the ability to forecast long-term cash generation potential for the firm's single-asset commercial model.
The sharp contraction in FCF margins during the most recent quarter suggests that the company's cash flow profile is highly sensitive to operational fluctuations. This inconsistency may imply that the business is still struggling to achieve a predictable steady-state cash flow as it balances commercial scaling with R&D investment.
According to the provided cash flow data, working capital changes have been a primary driver of quarterly cash flow, with a $49.6 million outflow in 2026Q1 contrasting sharply with a $74.0 million inflow in 2025Q4, highlighting significant sensitivity to channel inventory and receivables.
These dramatic swings in working capital suggest that the company's cash position is highly susceptible to the timing of specialty pharmacy shipments and payer reimbursement cycles. Such volatility warrants further investigation into whether these fluctuations represent genuine shifts in demand or merely accounting noise related to channel stuffing or destocking.
As indicated by historical cash flow statements, Harmony Biosciences has utilized its cash reserves for both inorganic growth and shareholder returns, including $44.5 million in acquisitions and $50.0 million in share repurchases during 2023Q4, reflecting a transition toward more aggressive capital deployment strategies.
The shift toward M&A, such as the Zynerba acquisition, suggests that management is actively attempting to mitigate single-product risk. However, the effectiveness of this capital deployment remains unproven, and investors should monitor whether these investments provide sufficient returns to offset the inherent risks of the core narcolepsy franchise.
Quick answers to the most common questions about buying HRMY stock.
Harmony Biosciences Holdings, Inc. (HRMY) generated $348.2M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Harmony Biosciences Holdings, Inc. (HRMY) generated $347.9M in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Harmony Biosciences Holdings, Inc. (HRMY) spent $19.6M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.