Ionis Pharmaceuticals, Inc. (IONS) Stock Price History
Historical prices from 1991 to 2026
- 1M
- +6.7%
- 3M
- -21.3%
- YTD
- -27.0%
- 1Y
- -3.9%
- 3Y
- +13.9%
- 5Y
- +8.0%
Loading 10-year price history...
IONS Historical Performance
IONS Annual Returns
Year-by-year price performance · 2002–2026
- 2002 annual price return
- -68.7%
- 2003 annual price return
- -5.0%
- 2004 annual price return
- -13.4%
- 2005 annual price return
- -9.7%
- 2006 annual price return
- +111.8%
- 2007 annual price return
- +44.1%
- 2008 annual price return
- -7.8%
- 2009 annual price return
- -23.2%
- 2010 annual price return
- -10.2%
- 2011 annual price return
- -29.9%
- 2012 annual price return
- +44.0%
- 2013 annual price return
- +268.2%
- 2014 annual price return
- +54.9%
- 2015 annual price return
- +0.6%
- 2016 annual price return
- -22.5%
- 2017 annual price return
- +6.3%
- 2018 annual price return
- +9.8%
- 2019 annual price return
- +12.3%
- 2020 annual price return
- -7.1%
- 2021 annual price return
- -46.4%
- 2022 annual price return
- +15.9%
- 2023 annual price return
- +34.6%
- 2024 annual price return
- -33.9%
- 2025 annual price return
- +128.0%
- 2026 annual price return
- -35.0%
IONS Stock Price Trajectory (1991–2026)
As of October 3, 2026, Ionis Pharmaceuticals, Inc. (IONS) trades at $58.13, representing a -3.9% return over the past year. The stock has delivered a +47.1% total return over five years (+8.0% CAGR), reflecting significant long-term value creation.
The stock reached its all-time high of $86.74 on July 8, 2026. From this peak, IONS has corrected -33.0%, currently trading 21% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers ALNY (-40.9% 1Y), SRPT (+21.3% 1Y), and BMRN (+12.6% 1Y), IONS has underperformed the peer group average. Compare IONS vs ALNY →
IONS Historical Price Data · from 1991
Rows 1–50 of 8,888| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-09-03 | 60.42 | 60.42 | 57.47 | 58.13 | 4.25M | -5.22% |
| 2026-09-02 | 60.25 | 61.77 | 59.83 | 61.33 | 1.83M | +2.42% |
| 2026-09-01 | 60.53 | 60.99 | 59.78 | 59.88 | 1.87M | -0.80% |
| 2026-08-31 | 60.94 | 60.94 | 59.70 | 60.36 | 2.02M | -1.13% |
| 2026-08-28 | 60.62 | 61.69 | 60.35 | 61.05 | 1.85M | -2.21% |
| 2026-08-27 | 63.20 | 63.23 | 62.34 | 62.43 | 1.62M | -1.47% |
| 2026-08-26 | 63.50 | 63.50 | 62.44 | 63.36 | 2.15M | -0.33% |
| 2026-08-25 | 62.19 | 64.18 | 62.19 | 63.57 | 2.43M | +2.47% |
| 2026-08-24 | 60.54 | 62.07 | 59.70 | 62.04 | 2.21M | +3.85% |
| 2026-08-21 | 59.64 | 60.92 | 59.06 | 59.74 | 2.72M | +1.67% |
| 2026-08-20 | 60.03 | 60.41 | 58.60 | 58.76 | 2.12M | -3.36% |
| 2026-08-19 | 60.11 | 61.36 | 59.61 | 60.80 | 3.14M | +1.98% |
| 2026-08-18 | 58.41 | 60.19 | 58.02 | 59.62 | 3.19M | +1.69% |
| 2026-08-17 | 57.11 | 58.74 | 56.41 | 58.63 | 2.00M | +2.43% |
| 2026-08-14 | 55.16 | 57.24 | 55.16 | 57.24 | 1.35M | +2.45% |
| 2026-08-13 | 56.50 | 56.81 | 55.56 | 55.87 | 1.22M | -1.17% |
| 2026-08-12 | 55.01 | 57.07 | 54.91 | 56.53 | 2.00M | +2.00% |
| 2026-08-11 | 56.79 | 57.16 | 55.37 | 55.42 | 2.41M | -2.67% |
| 2026-08-10 | 56.10 | 57.66 | 56.10 | 56.94 | 2.40M | +0.67% |
| 2026-08-07 | 54.73 | 56.60 | 54.40 | 56.56 | 2.01M | +3.80% |
| 2026-08-06 | 54.59 | 55.42 | 54.02 | 54.49 | 2.59M | +0.55% |
| 2026-08-05 | 55.17 | 55.36 | 53.58 | 54.19 | 2.12M | -1.60% |
| 2026-08-04 | 54.85 | 55.22 | 53.87 | 55.07 | 2.69M | +1.06% |
| 2026-08-03 | 52.66 | 54.54 | 52.17 | 54.49 | 3.21M | +5.25% |
| 2026-07-31 | 53.33 | 53.33 | 51.28 | 51.77 | 2.57M | -2.83% |
| 2026-07-30 | 53.92 | 54.04 | 52.65 | 53.28 | 2.88M | -1.41% |
| 2026-07-29 | 55.09 | 55.36 | 53.50 | 54.04 | 3.13M | -2.28% |
| 2026-07-28 | 56.56 | 56.56 | 54.00 | 55.30 | 2.81M | -1.18% |
| 2026-07-27 | 56.93 | 57.09 | 55.79 | 55.96 | 2.58M | -1.04% |
| 2026-07-24 | 56.32 | 57.36 | 56.19 | 56.55 | 3.09M | +1.22% |
| 2026-07-23 | 53.71 | 57.48 | 53.35 | 55.87 | 3.83M | +3.44% |
| 2026-07-22 | 51.16 | 54.06 | 50.01 | 54.01 | 8.73M | +1.16% |
| 2026-07-21 | 52.75 | 54.13 | 52.26 | 53.39 | 3.07M | +0.83% |
| 2026-07-20 | 54.47 | 54.80 | 52.82 | 52.95 | 2.17M | -2.65% |
| 2026-07-17 | 54.10 | 54.69 | 53.76 | 54.39 | 2.57M | -0.48% |
| 2026-07-16 | 53.95 | 55.98 | 53.38 | 54.65 | 3.81M | -0.15% |
| 2026-07-15 | 54.48 | 54.89 | 53.51 | 54.73 | 3.58M | -0.36% |
| 2026-07-14 | 55.80 | 56.46 | 54.53 | 54.93 | 4.70M | -3.21% |
| 2026-07-13 | 57.91 | 57.91 | 56.11 | 56.75 | 5.10M | -2.58% |
| 2026-07-10 | 64.27 | 64.44 | 58.20 | 58.25 | 11.44M | -9.37% |
| 2026-07-09 | 67.78 | 70.35 | 64.10 | 64.27 | 20.45M | -23.90% |
| 2026-07-08 | 85.56 | 86.74 | 83.92 | 84.46 | 2.28M | -2.17% |
| 2026-07-07 | 84.42 | 86.67 | 82.95 | 86.33 | 2.65M | +3.79% |
| 2026-07-06 | 82.11 | 84.01 | 81.19 | 83.18 | 1.85M | +1.69% |
| 2026-07-02 | 79.53 | 81.99 | 79.11 | 81.80 | 2.30M | +3.30% |
| 2026-07-01 | 79.13 | 79.48 | 77.95 | 79.19 | 1.44M | -0.13% |
| 2026-06-30 | 81.17 | 81.24 | 79.21 | 79.29 | 2.38M | -1.74% |
| 2026-06-29 | 81.00 | 82.53 | 79.95 | 80.69 | 2.81M | -0.60% |
| 2026-06-26 | 78.80 | 82.63 | 78.80 | 81.18 | 3.83M | +3.63% |
| 2026-06-25 | 76.69 | 79.55 | 76.25 | 78.34 | 2.58M | +2.38% |
IONS Chart Terminal
Live VCP patterns, Cup & Handle overlays, support/resistance, and AI trade plans.
Live Breakouts Feed
High-probability breakout stocks crossing their pivot across 5 pattern engines.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
IONS — Frequently Asked Questions
Quick answers to the most common questions about buying IONS stock.
How has IONS stock performed recently?
IONS declined -3.9% over the past year, below its 5-year annualized CAGR of +8.0%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is IONS's all-time high price?
Ionis Pharmaceuticals, Inc. reached $86.74 on 2026-07-08. The 52-week high is $86.74. Current 1-year return of -3.9% places the stock further from historical peaks.
Where can I download IONS historical price data?
This page provides IONS daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 1991-2026, downloadable in CSV format.