Ionis Pharmaceuticals, Inc. (IONS) Stock Price History
Historical prices from 1991 to 2026
- 1M
- +2.2%
- 3M
- +3.4%
- YTD
- -7.0%
- 1Y
- +100.3%
- 3Y
- +21.8%
- 5Y
- +14.4%
Loading 10-year price history...
IONS Historical Performance
IONS Annual Returns
Year-by-year price performance · 2002–2026
- 2002 annual price return
- -68.7%
- 2003 annual price return
- -5.0%
- 2004 annual price return
- -13.4%
- 2005 annual price return
- -9.7%
- 2006 annual price return
- +111.8%
- 2007 annual price return
- +44.1%
- 2008 annual price return
- -7.8%
- 2009 annual price return
- -23.2%
- 2010 annual price return
- -10.2%
- 2011 annual price return
- -29.9%
- 2012 annual price return
- +44.0%
- 2013 annual price return
- +268.2%
- 2014 annual price return
- +54.9%
- 2015 annual price return
- +0.6%
- 2016 annual price return
- -22.5%
- 2017 annual price return
- +6.3%
- 2018 annual price return
- +9.8%
- 2019 annual price return
- +12.3%
- 2020 annual price return
- -7.1%
- 2021 annual price return
- -46.4%
- 2022 annual price return
- +15.9%
- 2023 annual price return
- +34.6%
- 2024 annual price return
- -33.9%
- 2025 annual price return
- +128.0%
- 2026 annual price return
- +1.9%
IONS Stock Price Trajectory (1991–2026)
As of June 23, 2026, Ionis Pharmaceuticals, Inc. (IONS) trades at $74.12, representing a +100.3% return over the past year. The stock has delivered a +96.1% total return over five years (+14.4% CAGR), reflecting significant long-term value creation.
The stock reached its all-time high of $86.74 on February 5, 2026. From this peak, IONS has corrected -14.5%, currently trading 1% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers ALNY (-11.0% 1Y), SRPT (-15.6% 1Y), and BMRN (-1.0% 1Y), IONS has outperformed the peer group average. Compare IONS vs ALNY →
IONS Historical Price Data · from 1991
Rows 1–50 of 8,836| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-18 | 75.00 | 75.66 | 73.50 | 74.12 | 2.38M | -0.26% |
| 2026-06-17 | 73.09 | 75.12 | 72.55 | 74.31 | 1.79M | +1.68% |
| 2026-06-16 | 73.93 | 73.95 | 72.30 | 73.08 | 1.34M | -1.19% |
| 2026-06-15 | 73.49 | 74.27 | 72.89 | 73.96 | 1.49M | +0.93% |
| 2026-06-12 | 73.82 | 74.35 | 72.58 | 73.28 | 1.84M | -0.74% |
| 2026-06-11 | 73.34 | 74.47 | 72.76 | 73.82 | 1.87M | +0.68% |
| 2026-06-10 | 74.33 | 75.83 | 72.83 | 73.32 | 1.56M | -1.69% |
| 2026-06-09 | 74.14 | 75.79 | 73.53 | 74.58 | 1.55M | +1.41% |
| 2026-06-08 | 74.34 | 74.43 | 73.14 | 73.54 | 1.60M | -1.26% |
| 2026-06-05 | 75.50 | 75.95 | 73.81 | 74.48 | 1.84M | -0.87% |
| 2026-06-04 | 74.01 | 75.89 | 73.82 | 75.13 | 1.21M | +1.77% |
| 2026-06-03 | 72.68 | 74.12 | 72.02 | 73.82 | 1.27M | +1.16% |
| 2026-06-02 | 74.85 | 75.22 | 72.56 | 72.97 | 2.03M | -3.20% |
| 2026-06-01 | 75.67 | 76.19 | 74.70 | 75.38 | 1.32M | -1.46% |
| 2026-05-29 | 77.28 | 78.10 | 76.47 | 76.50 | 1.35M | -1.07% |
| 2026-05-28 | 76.58 | 78.00 | 75.34 | 77.33 | 1.58M | +1.10% |
| 2026-05-27 | 76.24 | 77.40 | 76.24 | 76.49 | 1.33M | +0.55% |
| 2026-05-26 | 76.00 | 76.73 | 74.73 | 76.07 | 711K | +0.67% |
| 2026-05-22 | 75.71 | 76.80 | 75.00 | 75.56 | 1.53M | -0.29% |
| 2026-05-21 | 74.41 | 76.48 | 74.21 | 75.78 | 2.25M | +0.96% |
| 2026-05-20 | 74.09 | 75.69 | 73.97 | 75.06 | 1.98M | +1.65% |
| 2026-05-19 | 72.81 | 74.15 | 72.00 | 73.84 | 1.48M | +1.82% |
| 2026-05-18 | 74.58 | 74.78 | 71.97 | 72.52 | 2.18M | -2.30% |
| 2026-05-15 | 75.89 | 75.93 | 73.32 | 74.23 | 2.12M | -1.92% |
| 2026-05-14 | 79.00 | 79.05 | 75.34 | 75.68 | 1.68M | -2.47% |
| 2026-05-13 | 75.48 | 78.03 | 75.08 | 77.60 | 1.36M | +2.33% |
| 2026-05-12 | 76.16 | 77.13 | 75.59 | 75.83 | 1.39M | +0.60% |
| 2026-05-11 | 75.97 | 77.01 | 74.85 | 75.38 | 1.46M | -0.44% |
| 2026-05-08 | 76.45 | 77.40 | 75.25 | 75.71 | 1.65M | -0.41% |
| 2026-05-07 | 76.44 | 76.56 | 74.87 | 76.02 | 1.68M | -1.08% |
| 2026-05-06 | 75.39 | 77.42 | 75.29 | 76.85 | 1.20M | +2.13% |
| 2026-05-05 | 75.84 | 76.45 | 74.84 | 75.25 | 463K | -0.27% |
| 2026-05-04 | 75.26 | 76.00 | 74.47 | 75.45 | 1.69M | +0.23% |
| 2026-05-01 | 74.86 | 76.15 | 72.94 | 75.28 | 1.66M | +0.70% |
| 2026-04-30 | 74.91 | 77.76 | 73.82 | 74.76 | 2.38M | -0.09% |
| 2026-04-29 | 73.65 | 74.95 | 71.30 | 74.83 | 3.63M | +4.25% |
| 2026-04-28 | 72.55 | 73.10 | 71.17 | 71.78 | 2.37M | -0.62% |
| 2026-04-27 | 74.00 | 75.00 | 72.21 | 72.23 | 2.05M | -1.42% |
| 2026-04-24 | 74.09 | 74.09 | 72.33 | 73.27 | 1.75M | -1.11% |
| 2026-04-23 | 74.96 | 76.06 | 73.23 | 74.09 | 1.34M | -0.99% |
| 2026-04-22 | 75.22 | 75.44 | 74.01 | 74.83 | 1.91M | +0.07% |
| 2026-04-21 | 75.87 | 75.87 | 73.80 | 74.78 | 1.72M | -0.12% |
| 2026-04-20 | 75.52 | 75.52 | 74.59 | 74.87 | 1.03M | -1.11% |
| 2026-04-17 | 75.66 | 76.33 | 74.98 | 75.71 | 1.69M | +0.60% |
| 2026-04-16 | 76.42 | 76.53 | 73.91 | 75.26 | 1.72M | -2.03% |
| 2026-04-15 | 77.10 | 77.18 | 75.77 | 76.82 | 1.10M | +0.08% |
| 2026-04-14 | 74.88 | 77.38 | 74.88 | 76.76 | 1.38M | +2.41% |
| 2026-04-13 | 75.16 | 77.17 | 74.56 | 74.95 | 1.52M | -0.29% |
| 2026-04-10 | 77.02 | 77.14 | 74.53 | 75.17 | 1.58M | -1.65% |
| 2026-04-09 | 74.98 | 76.97 | 74.62 | 76.43 | 1.20M | +1.93% |
Full Stock Analysis
Deep dive into IONS consensus models and risk factors.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
IONS — Frequently Asked Questions
Quick answers to the most common questions about buying IONS stock.
How has IONS stock performed recently?
IONS returned +100.3% over the past year, beating its 5-year annualized CAGR of +14.4%. The stock trades below its 200-day moving average, confirming the uptrend.
What is IONS's all-time high price?
Ionis Pharmaceuticals, Inc. reached $86.74 on 2026-02-05. The 52-week high is $86.74. Current 1-year return of +100.3% places the stock closer to historical peaks.
Where can I download IONS historical price data?
This page provides IONS daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 1991-2026, downloadable in CSV format.