19 years of historical data (2007–2025) · Healthcare · Drug Manufacturers - Specialty & Generic
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Ironwood Pharmaceuticals, Inc. trades at 25.5x earnings, 88% below its 5-year average of 211.1x, sitting at the 100th percentile of its historical range. Compared to the Healthcare sector median P/E of 22.1x, the stock trades at a premium of 15%. On a free-cash-flow basis, the stock trades at 5.0x P/FCF, 33% below the 5-year average of 7.4x.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $629M | $599M | $709M | $1.8B | $2.3B | $1.9B | $1.8B | $2.1B | $1.6B | $2.2B | $2.2B |
| Enterprise Value | $1.0B | $981M | $1.2B | $2.4B | $2.1B | $1.8B | $1.9B | $2.3B | $1.8B | $2.5B | $2.5B |
| P/E Ratio → | 25.47 | 22.47 | 805.45 | — | 12.91 | 3.63 | 17.26 | — | — | — | — |
| P/S Ratio | 2.12 | 2.02 | 2.02 | 4.02 | 5.62 | 4.63 | 4.70 | 4.85 | 4.56 | 7.49 | 8.14 |
| P/B Ratio | — | — | — | — | 3.54 | 3.16 | 29.21 | — | — | 226.79 | 33.44 |
| P/FCF | 4.95 | 4.72 | 6.86 | 9.71 | 8.44 | 7.33 | 10.96 | 587.29 | — | — | — |
| P/OCF | 4.95 | 4.72 | 6.85 | 9.69 | 8.43 | 7.32 | 10.84 | 193.63 | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
Ironwood Pharmaceuticals, Inc.'s enterprise value stands at 8.4x EBITDA, 9% below its 5-year average of 9.2x. The Healthcare sector median is 14.2x, placing the stock at a 41% discount on an enterprise-value basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 3.31 | 3.47 | 5.42 | 5.04 | 4.28 | 4.93 | 5.44 | 5.26 | 8.41 | 9.31 |
| EV / EBITDA | 8.38 | 8.14 | 12.82 | — | 8.21 | 7.58 | 13.10 | 18.54 | — | — | — |
| EV / EBIT | 8.51 | 9.55 | 12.75 | 12.26 | 7.95 | 7.63 | 13.87 | 18.95 | — | — | — |
| EV / FCF | — | 7.73 | 11.80 | 13.11 | 7.56 | 6.78 | 11.49 | 659.18 | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Ironwood Pharmaceuticals, Inc. earns an operating margin of 40.1%. Operating margins have expanded from -213.5% to 40.1% over the past 3 years, signaling improving operational efficiency. ROIC of 54.0% represents excellent returns on invested capital.
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 100.0% | 100.0% | 97.9% | 98.6% | 99.7% | 83.0% | 99.2% | 68.4% | 90.6% | 93.5% | 99.3% |
| Operating Margin | 40.1% | 40.1% | 26.5% | -213.5% | 61.0% | 56.1% | 36.7% | 28.0% | -68.9% | -25.9% | -18.9% |
| Net Profit Margin | 8.1% | 8.1% | 0.3% | -226.4% | 42.6% | 127.7% | 27.3% | 5.0% | -81.5% | -39.2% | -29.8% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | — | — | — | -654.9% | 27.8% | 158.1% | 169.5% | — | — | -305.5% | -101.0% |
| ROA | 6.4% | 6.4% | 0.2% | -127.5% | 15.7% | 62.7% | 22.1% | 5.9% | -60.2% | -17.8% | -12.3% |
| ROIC | 54.0% | 54.0% | 28.7% | -205.8% | 43.0% | 56.8% | 68.5% | 87.8% | -109.0% | -17.3% | -12.9% |
| ROCE | 50.9% | 50.9% | 36.7% | -148.9% | 24.5% | 31.1% | 32.2% | 41.8% | -63.5% | -13.4% | -8.9% |
Solvency and debt-coverage ratios — lower is generally safer
Ironwood Pharmaceuticals, Inc. carries a Debt/EBITDA ratio of 5.0x, which is highly leveraged (54% above the sector average of 3.2x). Net debt stands at $382M ($598M total debt minus $215M cash). Interest coverage of 3.1x is adequate, though a cyclical earnings downturn could tighten the margin of safety.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | — | — | — | 0.64 | 0.79 | 7.24 | — | — | 40.63 | 5.59 |
| Debt / EBITDA | 4.96 | 4.96 | 6.30 | — | 1.65 | 2.04 | 3.10 | 3.43 | — | — | — |
| Net Debt / Equity | — | — | — | — | -0.37 | -0.24 | 1.43 | — | — | 27.87 | 4.78 |
| Net Debt / EBITDA | 3.17 | 3.17 | 5.37 | — | -0.95 | -0.62 | 0.61 | 2.02 | — | — | — |
| Debt / FCF | — | 3.01 | 4.94 | 3.40 | -0.88 | -0.55 | 0.54 | 71.89 | — | — | — |
| Interest Coverage | 3.14 | 3.14 | 2.90 | 9.05 | 34.22 | 7.45 | 4.69 | 3.36 | -4.15 | -0.51 | -1.09 |
Short-term solvency ratios and asset-utilisation metrics
A current ratio of 1.13x means Ironwood Pharmaceuticals, Inc. can comfortably meet its short-term obligations, though there is limited excess liquidity. The current ratio has improved from 0.84x to 1.13x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.13 | 1.13 | 4.69 | 0.84 | 30.58 | 4.61 | 15.41 | 7.50 | 2.23 | 4.72 | 4.17 |
| Quick Ratio | 1.13 | 1.13 | 4.69 | 0.84 | 30.53 | 4.61 | 15.41 | 7.48 | 2.23 | 4.71 | 4.16 |
| Cash Ratio | 0.89 | 0.89 | 2.28 | 0.33 | 25.71 | 3.84 | 11.32 | 4.33 | 1.45 | 3.35 | 3.35 |
| Asset Turnover | — | 0.75 | 1.00 | 0.94 | 0.37 | 0.37 | 0.70 | 1.06 | 1.04 | 0.49 | 0.39 |
| Inventory Turnover | — | — | — | — | 1.13 | — | — | 208.93 | — | 26.40 | 1.73 |
| Days Sales Outstanding | — | 57.61 | 85.05 | 106.45 | 102.64 | 100.60 | 114.65 | 99.89 | 85.24 | 100.54 | 86.41 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Ironwood Pharmaceuticals, Inc. does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business. The earnings yield of 3.9% (inverse of P/E) provides a useful comparison to bond yields when assessing the stock's relative attractiveness to fixed income.
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | 3.9% | 4.5% | 0.1% | — | 7.7% | 27.5% | 5.8% | — | — | — | — |
| FCF Yield | 20.2% | 21.2% | 14.6% | 10.3% | 11.9% | 13.6% | 9.1% | 0.2% | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 5.5% | 1.3% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 5.5% | 1.3% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Shares Outstanding | — | $178M | $160M | $155M | $186M | $164M | $161M | $156M | $153M | $149M | $146M |
Compare IRWD with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
| $629M | 25.5 | 8.4 | 5.0 | 100.0% | 40.1% | — | 54.0% | 5.0 | |
| $7B | -56.1 | — | 131.9 | 97.3% | -343.6% | -20.2% | -21.8% | — | |
| $2B | -24.5 | — | — | 89.5% | -10.1% | -36.2% | -10.7% | — | |
| $83M | -29.3 | 33.0 | 17.3 | 85.0% | -6.3% | -12.0% | -8.6% | 4.1 | |
| $3B | -65.4 | 45.2 | 55.7 | 89.6% | -5.1% | -3.7% | -2.8% | 0.7 | |
| $1B | -0.9 | 7.0 | 9.2 | 35.1% | 8.1% | -39.3% | 3.7% | 5.8 | |
| $2M | -0.0 | — | — | — | — | -791.0% | -845.1% | — | |
| $355M | -1.6 | — | — | 94.0% | -70.0% | -50.9% | -32.2% | — | |
| $14B | -38.7 | 23.8 | 10.9 | 88.2% | 5.3% | -8.5% | 2.1% | 7.1 | |
| $893M | 141.9 | 9.6 | 6.5 | 79.4% | 4.6% | 1.0% | 2.3% | 3.7 | |
| $407B | 97.1 | 16.7 | 22.8 | 70.2% | 32.8% | 6214.7% | 23.9% | 2.4 | |
| Healthcare Median | — | 22.1 | 14.2 | 18.4 | 63.9% | -4.4% | -33.2% | -11.7% | 3.2 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Includes 30+ ratios · 19 years · Updated daily
DCF models, multiple analysis, and analyst estimates.
10-year return with dividends reinvested.
See how regular investing compounds over time.
Compare growth, multiples, and margins vs sector.
Quick answers to the most common questions about buying IRWD stock.
Ironwood Pharmaceuticals, Inc.'s current P/E ratio is 25.5x. The historical average is 14.1x. This places it at the 100th percentile of its historical range.
Ironwood Pharmaceuticals, Inc.'s current EV/EBITDA is 8.4x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 11.4x.
Based on historical data, Ironwood Pharmaceuticals, Inc. is trading at a P/E of 25.5x. This is at the 100th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
Ironwood Pharmaceuticals, Inc. has 100.0% gross margin and 40.1% operating margin. Operating margin above 20% indicates strong pricing power and cost efficiency.
Ironwood Pharmaceuticals, Inc.'s Debt/EBITDA ratio is 5.0x, indicating high leverage. A ratio above 4x may signal elevated financial risk.