Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in KYMR held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 11.7M | $974.5M | +31.0% | 14.331% | 0.05% |
| 2 | BAKER BROS. ADVISORS LP | 8.7M | $721.1M | 0.0% | 10.604% | 4.14% |
| 3 | Avoro Capital Advisors LLC | 7.5M | $622.6M | 0.0% | 9.155% | 6.37% |
| 4 | BVF INC/IL | 5.5M | $458.3M | 0.0% | 6.740% | 14.60% |
| 5 | BlackRock, Inc. | 5.1M | $421.5M | +1.1% | 6.199% | 0.01% |
| 6 | Atlas Venture Life Science Advisors, LLC | 4.6M | $381.3M | -1.8% | 5.607% | 48.26% |
| 7 | WELLINGTON MANAGEMENT GROUP LLP | 3.9M | $324.0M | -11.9% | 4.764% | 0.06% |
| 8 | Siren, L.L.C. | 3.2M | $265.4M | -3.0% | 3.903% | 7.36% |
| 9 | VANGUARD CAPITAL MANAGEMENT LLC | 2.9M | $239.9M | — | 3.528% | 0.01% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.9M | $239.4M | — | 3.520% | 0.01% |
| 11 | STATE STREET CORP | 2.4M | $199.0M | +8.1% | 2.927% | 0.01% |
| 12 | Capital Research Global Investors | 1.7M | $139.4M | +7.2% | 2.050% | 0.02% |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 1.6M | $137.1M | +16.1% | 2.015% | 0.01% |
| 14 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1.0M | $86.9M | -2.4% | 1.278% | 0.64% |
| 15 | UBS Group AG | 1.0M | $85.3M | +38.9% | 1.254% | 0.01% |
| 16 | GOLDMAN SACHS GROUP INC | 888K | $74.0M | +20.0% | 1.088% | 0.01% |
| 17 | UBS ASSET MANAGEMENT AMERICAS INC | 876K | $73.0M | -4.0% | 1.073% | 0.02% |
| 18 | Holocene Advisors, LP | 837K | $69.7M | +9.9% | 1.025% | 0.17% |
| 19 | ALLIANCEBERNSTEIN L.P. | 888K | $69.1M | -6.7% | 1.088% | 0.02% |
| 20 | Merck & Co., Inc. | 772K | $64.3M | 0.0% | 0.946% | 18.40% |
| 21 | FRONTIER CAPITAL MANAGEMENT CO LLC | 760K | $63.3M | +19.5% | 0.931% | 0.65% |
| 22 | COMMODORE CAPITAL LP | 750K | $62.5M | 0.0% | 0.919% | 3.61% |
| 23 | EVENTIDE ASSET MANAGEMENT, LLC | 627K | $52.2M | +0.1% | 0.768% | 0.86% |
| 24 | DIMENSIONAL FUND ADVISORS LP | 593K | $49.4M | -5.0% | 0.726% | 0.01% |
| 25 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 561K | $46.7M | 0.0% | 0.687% | 0.55% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in KYMR — a direct measure of their conviction.
Filings activity in KYMR during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 252 | +0.4% | 100.12% | +8.40 pp | $7.05B | +9.2% |
| Q4 2025 | 251 | +21% | 91.72% | +31.26 pp | $6.45B | +52% |
| Q3 2025 | 208 | 0.5% | 60.46% | +16.14 pp | $4.26B | +36% |
| Q2 2025 | 209 | +22% | 44.32% | +18.70 pp | $3.12B | +73% |
| Q1 2025 | 171 | 5.0% | 25.62% | 11.00 pp | $1.80B | 30% |
| Q4 2024 | 180 | +2.9% | 36.62% | 5.03 pp | $2.58B | 12% |
| Q3 2024 | 175 | +11% | 41.65% | +15.97 pp | $2.93B | +62% |
| Q2 2024 | 157 | — | 25.68% | — | $1.81B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying KYMR stock.
Based on Q1 2026 13F filings, institutional ownership of Kymera Therapeutics, Inc. stands at 100.1%, held across 252 reporting institutions.
FMR LLC is the largest reported institutional holder of KYMR, with approximately 11,699,950 shares worth $0.97B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of KYMR.
Our composite Smart Money Score for KYMR is 47 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
44 institutions opened new positions in KYMR during Q1 2026, while 43 fully exited. 158 added to existing positions and 48 trimmed.
KYMR institutional ownership rose by 8.40 percentage points quarter-over-quarter, with a net change of +1 holders.
The top 10 institutions account for 66.0% of all reported 13F value in KYMR, and the top 25 account for 84.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Kymera Therapeutics, Inc. (KYMR) Institutional Ownership