Cash flow conversion remains inconsistent, highlighted by an operating cash flow to net income ratio of negative 3.65 in 2026Q1, reflecting a persistent disconnect between GAAP earnings and actual cash generation.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 | Dec'98 | Dec'97 | Dec'96 |
|---|
| Cash from Operations | 123.42M | 49.36M | 97.05M | 49.58M | 137.85M | 78.8M | 54.59M | -29.34M | 194.06M | 93.57M | 63M | 41.73M | 20.57M | 20.69M | 161K | -1.17M | -27.07M | -33.8M | -20.63M | -97.73M | -138.52M | 8.37M | 5.75M | 274K | -25.11M | -19.91M | -47.35M | -60.5M | -66.6M | -13.4M | -33.3M |
| Operating CF Margin % | - | 18.41% | 58.07% | 37.75% | 70.24% | 32.62% | 33.37% | -24.39% | 77.18% | 66.31% | 57.81% | 58.02% | 31.87% | 42.25% | 0.51% | -3.9% | -114.99% | -86.8% | -75.51% | -757.93% | -98.27% | 4.74% | 3.52% | 0.19% | -25.99% | -26.08% | -98.43% | -147.92% | -376.27% | -25.92% | -90.49% |
| Operating CF Growth % | 306.33% | -49.14% | 95.75% | -64.04% | 74.94% | 44.36% | 286.07% | -115.12% | 107.4% | 48.52% | 50.98% | 102.89% | -0.6% | 12750.93% | 113.74% | 95.67% | 19.92% | -63.88% | 78.9% | 29.45% | -1755.96% | 45.38% | 2000% | 101.09% | -26.15% | 57.96% | 21.73% | 9.16% | -397.01% | 59.76% | 12.14% |
| Net Income | 153.56M | 124.45M | -4.03M | 52.15M | -33.36M | 57.14M | -2.98M | 629.3M | 143.32M | 12.56M | -2.37M | 254.93M | 10.89M | 8.83M | -2.67M | 10.17M | -12.79M | -8.34M | -98.11M | 281.69M | -31.74M | -36.4M | -45.14M | -37.46M | -32.6M | -42.99M | -59.28M | -74.7M | -117.9M | -100.2M | -37.3M |
| Depreciation & Amortization | 33.63M | 35.72M | 35.24M | 36.52M | 51.37M | 50.95M | 27.97M | 43.73M | 14.72M | 11.71M | 11.29M | 2.63M | 2.66M | 2.66M | 2.73M | 2.79M | 2.21M | 3.13M | 1.05M | 2.62M | 16.22M | 18.71M | 15.28M | 14.28M | 10.47M | 6.57M | 6.97M | 7.4M | 7.7M | 9.8M | 9.4M |
| Stock-Based Compensation | 39.61M | 0 | 41.09M | 25.74M | 60.28M | 38.78M | 30.73M | 24.52M | 20.85M | 24.91M | 18.89M | 12.46M | 11.27M | 5.67M | 4.07M | 3.35M | 2.33M | 3.37M | -537K | 7.58M | 5.34M | 107K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | -325K | 22.68M | -15.8M | 11.7M | 20.72M | -8.62M | -19.05M | 74.83M | 29.74M | 44.52M | 10.7M | -219.61M | 410K | 374K | -1.2M | -13.26M | 5.99M | -22.8M | -1.36M | -5.79M | -9.66M | -107K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -101.44M | -120.83M | 21.2M | -42.13M | -26.84M | -7.29M | 28M | -797.5M | 24.29M | 11.3M | 35.11M | -9.49M | 6.29M | 3.86M | 13K | 1.65M | -68K | 9.17M | 79.64M | -327.99M | -36.01M | -578K | -5.57M | 8.59M | 3.83M | 16.56M | -2.79M | 15.5M | 45.1M | 64.9M | -1.4M |
| Working Capital Changes | -1.61M | -12.66M | 19.36M | -34.4M | 65.68M | -52.16M | -10.06M | -4.21M | -38.85M | -11.44M | -10.62M | 821K | -10.95M | -702K | -2.77M | -5.88M | -24.74M | -18.33M | -1.31M | -55.83M | -82.66M | 26.64M | 41.19M | 14.86M | -6.81M | -42K | 7.74M | -8.7M | -1.5M | 12.1M | -4M |
| Change in Receivables | -14.75M | -21.74M | -6.46M | -2.6M | 55.32M | -28.62M | -26.06M | 25.46M | -29.54M | -8.36M | -8.53M | 6.49M | -10.41M | 2.37M | 1.52M | -3.92M | -375K | -618K | 0 | 11.54M | 9.43M | 0 | -11.95M | -6.88M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 1.35M | 4.99M | 9.62M | -10.87M | 12.06M | -427K | -17.8M | -2.06M | -2.56M | -843K | -244K | -401K | 4.37M | 646K | 1.03M | 1.11M | -3.93M | -448K | 0 | 930K | 1.58M | -3.43M | -3.29M | -3.42M | -1.08M | 1.9M | 81K | 400K | -2.9M | 0 | 0 |
| Change in Payables | 10.74M | 5.88M | 0 | -4.7M | -3.34M | -1.17M | -1.25M | -18.05M | -4.54M | -1.71M | -2.37M | -4.03M | -3.15M | -2.76M | -4.8M | -11.57M | -13.45M | -10.99M | 0 | -51.89M | -27.64M | 0 | 9.75M | 24.52M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | -476.56M | -377.32M | -143.66M | -11.68M | 163.62M | 30.52M | 231.65M | 466.92M | -423.27M | -84.18M | -143.19M | -112.86M | -2.03M | -4.97M | 1.26M | -25.13M | 14.54M | 24.77M | -24.42M | 343.84M | 196.87M | -33.72M | 19.61M | -24.62M | -105.25M | -4.17M | 14.65M | -24.9M | -28.6M | 4.3M | 7.5M |
| Capital Expenditures | -466K | -11.31M | -1.82M | -3.52M | -17.92M | -8.76M | -4.46M | -2.55M | -11.89M | -7.15M | -28.32M | -10.86M | -4.5M | -4.94M | -8.64M | -78K | -70K | -522K | -495K | -440K | -1.78M | -35.6M | -3.6M | -2.78M | -3.16M | -1.97M | -1.08M | -39.5M | -2.4M | -4.3M | -400K |
| CapEx % of Revenue | 0.17% | 4.22% | 1.09% | 2.68% | 9.13% | 3.63% | 2.73% | 2.12% | 4.73% | 5.07% | 25.99% | 15.11% | 6.97% | 10.08% | 27.54% | 0.26% | 0.3% | 1.34% | 1.81% | 3.41% | 1.26% | 20.16% | 2.2% | 1.97% | 3.27% | 2.59% | 2.26% | 96.58% | 13.56% | 8.32% | 1.09% |
| Acquisitions | 0 | -8.09M | -172.19M | -25.65M | -750K | 494K | -383.32M | -12.84M | -5.86M | -26.65M | -94.2M | -9.25M | -3.49M | -989K | 0 | -32.02M | -2.83M | 9.8M | 4.13M | 310.14M | 183.33M | 0 | 0 | 0 | 0 | 0 | -200K | 0 | 100K | 100K | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -13.74M | -4.34M | -12.89M | -49.91M | -868K | -1.22M | 3.26M | 808.13M | 3.91M | 7.25M | 300K | -15.99M | 130K | -37K | -93K | -2.38M | -1.01M | 539K | 8.29M | 39.59M | 8.14M | 181K | -131K | -3.86M | -106.2M | 281K | 11.88M | -5.2M | -9.3M | -16.8M | -200K |
| Cash from Financing | 418.84M | 428.22M | 97.14M | -59.95M | -275.99M | -137.76M | -310.55M | -485.17M | 328.58M | -7.52M | 1.51M | 8.36M | 130.03M | -16.46M | 3.92M | 30M | -159K | -3.69M | -3.01M | -327.7M | 33.3M | -201K | 7.92M | 40.95M | 152.04M | 35.59M | 12.03M | 82.5M | 65.8M | 36.5M | 44.7M |
| Debt Issued (Net) | 338.11M | 338.11M | -25K | -76.9M | -261M | -146.01M | -231.76M | -27.32M | 532.33M | 0 | 0 | 0 | 235.63M | -19.59M | -2.5M | 30M | -91K | -3.92M | -1.53M | -2.17M | 24.4M | -1.1M | 1.49M | -1.35M | 99.38M | 7.96M | -2.75M | 59.6M | 27M | -700K | 2.4M |
| Equity Issued (Net) | 103.32M | 99.89M | 37.14M | 0 | -8.24M | 15.32M | -78M | -457.47M | -126.63M | -1.97M | 2.51M | -489K | -67.95M | 3.13M | 5.44M | -55K | -68K | 228K | -1.48M | -35.22M | 9.05M | 930K | 6.62M | 33.58M | 70.75M | 28.58M | 14.19M | 22.3M | 38.3M | 36.7M | 39M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -252.56M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -15M | -15M | 0 | 0 | -8.24M | -18.45M | -78M | -453.05M | -122.87M | -1.97M | -3.9M | -489K | -67.95M | 0 | 0 | -55K | -91K | 0 | -1.61M | -39.61M | 0 | 0 | 0 | -15.87M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -22.59M | -9.77M | 60.03M | 16.95M | -6.75M | -7.07M | -789K | -383K | -77.11M | -5.56M | -999K | 8.85M | -37.66M | 0 | 979K | 54K | 0 | 0 | 0 | -37.56M | -153K | -35K | -189K | 8.72M | -18.09M | -936K | 577K | 600K | 500K | 500K | 3.3M |
| Net Change in Cash | 67.11M | 102.62M | 49.35M | -22.05M | 25.48M | -28.44M | -24.31M | -47.51M | 99.16M | 1.87M | -78.68M | -62.77M | 148.56M | -742K | 5.34M | 3.69M | -12.69M | -12.72M | -48.06M | -81.59M | 91.64M | -25.55M | 33.28M | 16.61M | 21.68M | 11.52M | -20.68M | -2.9M | -29.5M | 27.4M | 18.9M |
| Free Cash Flow | 122.96M | 48.91M | 77.41M | -4.27M | 119.93M | 70.04M | 50.13M | -31.89M | 182.17M | 86.41M | 34.68M | 30.86M | 16.07M | 15.75M | -8.48M | -1.25M | -27.14M | -34.32M | -21.12M | -98.17M | -140.3M | -27.23M | 2.15M | -2.51M | -28.27M | -21.88M | -48.44M | -100M | -69M | -17.7M | -33.7M |
| FCF Margin % | 44.8% | 18.24% | 46.31% | -3.25% | 61.11% | 29% | 30.65% | -26.51% | 72.45% | 61.24% | 31.82% | 42.92% | 24.9% | 32.17% | -27.03% | -4.16% | -115.29% | -88.14% | -77.32% | -761.34% | -99.53% | -15.42% | 1.31% | -1.78% | -29.26% | -28.66% | -100.69% | -244.5% | -389.83% | -34.24% | -91.58% |
| FCF Growth % | 246.42% | -36.82% | 1911.96% | -103.56% | 71.23% | 39.72% | 257.2% | -117.5% | 110.81% | 149.18% | 12.36% | 92.1% | 1.99% | 285.7% | -578.64% | 95.39% | 20.94% | -62.51% | 78.49% | 30.03% | -415.24% | -1366.56% | 185.69% | 91.13% | -29.22% | 54.83% | 51.56% | -44.93% | -289.83% | 47.48% | 11.55% |
| FCF per Share | 6.18 | 2.41 | 4.23 | -0.24 | 7.11 | 4.06 | 3.10 | -1.61 | 7.57 | 3.68 | 1.66 | 1.45 | 0.75 | 0.76 | -0.43 | -0.06 | -1.38 | -1.82 | -1.33 | -6.00 | -10.44 | -2.21 | 0.18 | -0.21 | -2.45 | -2.21 | -5.22 | -12.73 | -10.25 | -3.21 | -7.03 |
| FCF Conversion (FCF/Net Income) | 0.80x | 0.40x | -24.07x | 0.95x | -4.13x | 1.38x | -18.29x | -0.05x | 1.35x | 7.45x | -38.51x | 0.16x | 1.71x | 1.81x | -0.31x | -0.12x | 2.16x | 17.35x | 0.21x | -0.35x | 4.36x | -0.23x | -0.13x | -0.01x | 0.77x | 0.46x | 0.65x | 0.81x | 0.56x | 0.13x | 0.89x |
| Interest Paid | 98K | 0 | 263K | 288K | 1.43M | 3.03M | 4.46M | 5.83M | 1.51M | 1.84M | 1.84M | 1.82M | 494K | 1.82M | 0 | 2.46M | 58K | 270K | 229K | 1.51M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 621K | 0 | 19.21M | 8.77M | 11.64M | 3.72M | 2.13M | 103.82M | 341K | 157K | 38K | 28K | 18K | 26K | 0 | 39K | 28K | 14K | 140K | 8.37M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High Revenue Concentration Volatility
As reported in financial statements, Ligand's operating cash flow to net income ratio has fluctuated wildly, reaching a negative 3.65 in 2026Q1, which highlights a persistent and significant divergence between GAAP accounting results and the actual cash-generating capacity of the underlying royalty and material sales business model.
The frequent disconnect between net income and operating cash flow suggests that non-cash charges and timing differences in milestone recognition are heavily distorting the company's reported profitability. Investors should monitor whether this volatility is a structural feature of the royalty-aggregator model or a sign of aggressive revenue recognition practices that may not translate into long-term cash accumulation.
Based on recent SEC filings, Ligand's free cash flow trajectory remains highly erratic, with margins swinging from a negative 56.8% in 2025Q1 to a robust 93.7% in 2026Q1, underscoring the extreme sensitivity of cash generation to the timing of milestone payments and lumpy Captisol material orders.
The lack of a stable free cash flow trend complicates the valuation of the company as a predictable cash-generating entity. This pattern suggests that the business is currently more of a series of transactional events rather than a steady-state royalty stream, which warrants caution when projecting future liquidity and capital allocation capacity.
According to quarterly data, working capital changes have been a major source of cash flow instability, ranging from a $11.6M inflow in 2024Q4 to a $16.0M outflow in 2023Q4, indicating that the company's cash position is highly susceptible to the timing of partner payments and inventory management.
The volatility in working capital suggests that Ligand's cash conversion cycle is not yet optimized, potentially due to the diverse nature of its partner base and the varying payment terms associated with different royalty and material contracts. This inconsistency in cash collection cycles may necessitate higher cash buffers than a more mature royalty aggregator would typically require.
As indicated in financial disclosures, Ligand has consistently utilized its cash reserves for net acquisitions, such as the $96.2M outflow in 2024Q3, while largely eschewing dividends and maintaining a sporadic approach to share repurchases, which suggests a management strategy focused on aggressive portfolio expansion over direct shareholder returns.
The reliance on acquisitions to drive growth implies that the company must continuously deploy capital to replace aging assets, which creates a perpetual need for liquidity. Investors should scrutinize the return on invested capital for these acquisitions, as the current strategy appears to prioritize top-line growth through deal-making rather than organic cash flow compounding.
Based on reported figures, stock-based compensation has been a material non-cash expense, peaking at $26.2M in 2024Q3, which effectively masks the true economic cost of operations and creates a persistent gap between reported earnings and the cash-based reality of the company's compensation structure.
The significant reliance on stock-based compensation suggests that the company's reported cash flow from operations may be artificially bolstered by the exclusion of these equity-based costs. This practice warrants further investigation to determine if the dilution to shareholders is being adequately offset by the growth in the underlying royalty portfolio.
Quick answers to the most common questions about buying LGND stock.
Ligand Pharmaceuticals Incorporated (LGND) generated $49.4M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Ligand Pharmaceuticals Incorporated (LGND) generated $48.9M in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Ligand Pharmaceuticals Incorporated (LGND) spent $11.3M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Ligand Pharmaceuticals Incorporated (LGND) spent $15.0M on share repurchases. This shows the company's commitment to returning capital to its equity investors.