30 years of historical data (1995–2024) · Healthcare · Biotechnology
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Ligand Pharmaceuticals Incorporated currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis. On a free-cash-flow basis, the stock trades at 53.1x P/FCF, 102% above the 5-year average of 26.2x.
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $4.1B | $2.0B | $1.3B | $1.1B | $2.7B | $1.6B | $2.1B | $3.3B | $3.2B | $2.1B | $2.3B |
| Enterprise Value | $4.0B | $1.9B | $1.3B | $1.2B | $3.0B | $2.0B | $2.6B | $3.2B | $3.2B | $2.2B | $2.3B |
| P/E Ratio → | -949.77 | — | 24.29 | — | 46.25 | — | 3.27 | 22.77 | 258.36 | — | 8.95 |
| P/S Ratio | 24.57 | 11.73 | 9.66 | 5.74 | 11.03 | 9.84 | 17.13 | 12.99 | 22.79 | 19.42 | 32.00 |
| P/B Ratio | 4.60 | 2.36 | 1.81 | 1.89 | 3.24 | 2.27 | 2.69 | 5.82 | 7.68 | 5.71 | 7.56 |
| P/FCF | 53.06 | 25.32 | — | 9.40 | 38.03 | 32.11 | — | 17.93 | 37.21 | 61.04 | 74.57 |
| P/OCF | 42.32 | 20.19 | 25.58 | 8.17 | 33.81 | 29.49 | — | 16.83 | 34.36 | 33.60 | 55.16 |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
Ligand Pharmaceuticals Incorporated's enterprise value stands at 319.9x EBITDA, 537% above its 5-year average of 50.2x. The Healthcare sector median is 14.9x, placing the stock at a 2048% premium on an enterprise-value basis.
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 11.34 | 9.53 | 5.96 | 12.29 | 12.34 | 21.94 | 12.66 | 22.95 | 20.08 | 32.08 |
| EV / EBITDA | 319.95 | 149.97 | 25.82 | 25.19 | 19.18 | 30.83 | 3.10 | 17.65 | 40.18 | 39.67 | 77.00 |
| EV / EBIT | — | 341.06 | 19.46 | 30.93 | 32.33 | 70.31 | 3.17 | 14.37 | 47.18 | 105.21 | 84.40 |
| EV / FCF | — | 24.48 | — | 9.75 | 42.39 | 40.26 | — | 17.48 | 37.47 | 63.11 | 74.74 |
Margins and return-on-capital ratios measuring operating efficiency
Ligand Pharmaceuticals Incorporated earns an operating margin of -13.5%. Operating margins have compressed from 1.5% to -13.5% over the past 3 years, signaling potential cost pressures or competitive headwinds. A negative ROE of -0.5% indicates the company is currently destroying shareholder equity.
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 93.4% | 93.4% | 73.3% | 73.1% | 74.3% | 81.4% | 90.6% | 97.5% | 96.2% | 94.9% | 91.9% |
| Operating Margin | -13.5% | -13.5% | 9.1% | 1.5% | 43.0% | 22.9% | 671.0% | 65.1% | 48.2% | 40.3% | 38.0% |
| Net Profit Margin | -2.4% | -2.4% | 39.7% | -17.0% | 23.7% | -1.8% | 523.2% | 57.0% | 8.9% | -1.5% | 357.8% |
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -0.5% | -0.5% | 8.0% | -4.7% | 7.5% | -0.4% | 94.8% | 29.3% | 3.2% | -0.5% | 156.5% |
| ROA | -0.5% | -0.5% | 6.7% | -3.2% | 4.3% | -0.2% | 45.7% | 14.8% | 2.0% | -0.3% | 65.0% |
| ROIC | -2.3% | -2.3% | 1.4% | 0.3% | 6.9% | 2.3% | 66.3% | 26.7% | 11.5% | 8.8% | 11.3% |
| ROCE | -2.7% | -2.7% | 1.7% | 0.3% | 8.2% | 2.7% | 60.8% | 20.3% | 16.9% | 9.9% | 7.3% |
Solvency and debt-coverage ratios — lower is generally safer
Ligand Pharmaceuticals Incorporated carries a Debt/EBITDA ratio of 0.6x, which is very conservative (81% below the sector average of 3.0x). The company holds a net cash position — cash of $72M exceeds total debt of $7M, providing substantial financial flexibility for buybacks, acquisitions, or weathering downturns.
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.01 | 0.01 | 0.01 | 0.15 | 0.40 | 0.64 | 0.85 | 1.13 | 0.54 | 0.57 | 0.67 |
| Debt / EBITDA | 0.56 | 0.56 | 0.13 | 1.89 | 2.10 | 6.97 | 0.76 | 3.53 | 2.79 | 3.86 | 6.86 |
| Net Debt / Equity | — | -0.08 | -0.02 | 0.07 | 0.37 | 0.58 | 0.75 | -0.15 | 0.05 | 0.19 | 0.02 |
| Net Debt / EBITDA | -5.16 | -5.16 | -0.35 | 0.92 | 1.97 | 6.24 | 0.68 | -0.45 | 0.28 | 1.30 | 0.17 |
| Debt / FCF | — | -0.84 | — | 0.36 | 4.35 | 8.16 | — | -0.45 | 0.26 | 2.07 | 0.17 |
| Interest Coverage | -7.44 | -7.44 | 18.20 | 1.69 | 5.29 | 1.37 | 22.58 | 3.39 | 5.97 | 3.60 | 2.32 |
Net cash position: cash ($72M) exceeds total debt ($7M)
Short-term solvency ratios and asset-utilisation metrics
Ligand Pharmaceuticals Incorporated's current ratio of 8.93x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The quick ratio of 8.55x is notably lower than the current ratio, indicating a significant portion of current assets is tied up in inventory. The current ratio has improved from 2.67x to 8.93x over the past 3 years.
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 8.93 | 8.93 | 14.15 | 2.67 | 11.15 | 5.00 | 66.09 | 10.58 | 0.99 | 0.72 | 10.35 |
| Quick Ratio | 8.55 | 8.55 | 12.72 | 2.53 | 10.50 | 4.74 | 65.66 | 10.50 | 0.97 | 0.71 | 10.27 |
| Cash Ratio | 6.90 | 6.90 | 10.15 | 2.14 | 8.19 | 4.11 | 62.93 | 9.30 | 0.84 | 0.62 | 9.61 |
| Asset Turnover | — | 0.18 | 0.17 | 0.26 | 0.19 | 0.12 | 0.08 | 0.20 | 0.21 | 0.18 | 0.13 |
| Inventory Turnover | 0.78 | 0.78 | 1.46 | 3.97 | 2.28 | 1.15 | 1.56 | 0.89 | 1.23 | 2.90 | 3.56 |
| Days Sales Outstanding | — | 92.70 | 109.27 | 65.17 | 138.49 | 131.81 | 126.69 | 81.07 | 66.21 | 61.02 | 59.30 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Ligand Pharmaceuticals Incorporated does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business.
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 | FY 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | 4.1% | — | 2.2% | — | 30.5% | 4.4% | 0.4% | — | 11.2% |
| FCF Yield | 1.9% | 3.9% | — | 10.6% | 2.6% | 3.1% | — | 5.6% | 2.7% | 1.6% | 1.3% |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.7% | 0.7% | 4.8% | 22.0% | 3.8% | 0.1% | 0.2% | 0.0% |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.7% | 0.7% | 4.8% | 22.0% | 3.8% | 0.1% | 0.2% | 0.0% |
| Shares Outstanding | — | $18M | $18M | $17M | $17M | $16M | $20M | $24M | $23M | $21M | $21M |
Compare LGND with 7 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
| $4B | -949.8 | 319.9 | 53.1 | 93.4% | -13.5% | -0.5% | -2.3% | 0.6 | |
| $27B | 26.6 | 22.5 | 10.8 | — | 65.6% | 7.7% | 6.7% | 5.7 | |
| $2B | 6.9 | 5.6 | 8.7 | 72.3% | 38.5% | 29.1% | 16.8% | — | |
| $773M | 38.9 | 21.6 | 2.8 | 100.0% | 87.7% | 1.9% | 1.4% | — | |
| $317M | -15.6 | — | — | 99.3% | -140.3% | -16.2% | -37.6% | — | |
| $316M | -16.0 | — | — | 99.3% | -140.3% | -16.2% | -37.6% | — | |
| $99M | -0.3 | — | — | 100.0% | -6062.8% | -115.3% | -86.2% | — | |
| $1M | -0.0 | — | — | — | — | — | — | — | |
| Healthcare Median | — | 23.2 | 14.9 | 19.0 | 65.8% | -6.4% | -36.7% | -13.6% | 3.0 |
Peers based on L4 peer group classification. Compare multiple stocks →
Includes 30+ ratios · 30 years · Updated daily
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Start ComparisonLigand Pharmaceuticals Incorporated's current P/E ratio is -949.8x. The historical average is 35.6x.
Ligand Pharmaceuticals Incorporated's current EV/EBITDA is 319.9x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 35.7x.
Ligand Pharmaceuticals Incorporated's return on equity (ROE) is -0.5%. The historical average is -45.9%.
Based on historical data, Ligand Pharmaceuticals Incorporated is trading at a P/E of -949.8x. Compare with industry peers and growth rates for a complete picture.
Ligand Pharmaceuticals Incorporated has 93.4% gross margin and -13.5% operating margin.
Ligand Pharmaceuticals Incorporated's Debt/EBITDA ratio is 0.6x, indicating low leverage. A ratio below 2x is generally considered financially healthy.