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HomeStocksMCRBInstitutional Holders

MCRB logoSeres Therapeutics, Inc. (MCRB) Institutional Ownership

Q2 2026 13F Data|Updated 2026-11-07

✨

Institutional ownership decreased this quarter (-2.71 pp), while top 10 holders maintain a highly concentrated 91.8% of value.

Institutional Ownership
Can exceed 100% due to securities lending, short interest, and reporting timing differences.
24.7%$19M total value · ▼ 2.71 pp vs prior quarter
Smart Money Score
Based on ownership concentration, fund quality, buying/selling activity, ownership indicators, and institutional trend.
45 / 100Neutral
Institutions & Flow36 holders0 net flow (+6 / -6)

AI Insights & Key Takeaways

  • Positive Institutional Flow (+0)
  • Susquehanna International Group, Llp and Citadel Advisors Llc maintain significant positions
  • Top 10 holders control 91.8% of institutional value
  • No Insider Signal

Top Institutional Holders of MCRB

Ranked by reported Q2 2026 13F market value

Top 10 Holders
91.8%
Top 25 Holders
99.9%

Share of total reported institutional value in MCRB held by the largest 10 / 25 filers.

#InstitutionShares HeldMarket ValueQoQ ChangeOwnership %% of Fund
1Flagship Pioneering, LLC1.2M$9.1M0.0%11.936%0.59%
2VANGUARD CAPITAL MANAGEMENT LLC288K$2.3M-2.2%2.972%0.00%
3MARSHALL WACE, LLP172K$1.4M+23.4%1.779%0.00%

Quarterly Institutional Activity

Filings activity in MCRB during Q2 2026, grouped by how each filer changed its position.

OverviewNew Buyers6Added To5Trimmed23Exited6
  • XTX Topco Ltd$164K
  • GOLDMAN SACHS GROUP INC$120K
  • JPMORGAN CHASE & CO

MCRB Institutional Ownership by Quarter

8 quarters of 13F filings · Δ columns show change vs prior quarter

QuarterInst. HoldersΔ HoldersOwnership %Δ OwnershipTotal 13F ValueΔ Value
Q2 202636+2.9%24.67%2.71 pp$19M15%
Q1 2026357.9%27.38%1.74 pp$22M46%
Q4 2025382.6%29.12%6.37 pp$41M28%
Q3 202539+18%35.49%+7.84 pp$57M+115%
Q2 20253348%27.65%8.11 pp$27M38%
Q1 2025647.2%

MCRB — Frequently Asked Questions

Quick answers to the most common questions about buying MCRB stock.

What percentage of MCRB is owned by institutions?

Based on Q2 2026 13F filings, institutional ownership of Seres Therapeutics, Inc. stands at 24.7%, held across 36 reporting institutions.

Who is the largest institutional holder of MCRB?

Flagship Pioneering, LLC is the largest reported institutional holder of MCRB, with approximately 1,155,850 shares worth $0.01B as of Q2 2026.

Is MCRB a hedge fund favorite?

Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of MCRB, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC.

What is MCRB's Smart Money Score?

Our composite Smart Money Score for MCRB is 45 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.

How many institutions bought MCRB this quarter?
4SUSQUEHANNA INTERNATIONAL GROUP, LLP133K$1.1M-41.3%1.376%0.00%
5Vontobel Holding Ltd.123K$970K-11.2%1.270%0.00%
6BlackRock, Inc.111K$876K+8.8%1.146%0.00%
7GEODE CAPITAL MANAGEMENT, LLC80K$631K+6.9%0.826%0.00%
8CITADEL ADVISORS LLC54K$426K-9.2%0.558%0.00%
9VANGUARD FIDUCIARY TRUST CO49K$384K+22.8%0.503%0.00%
10STATE STREET CORP34K$267K0.0%0.350%0.00%
11Lion Point Capital, LP32K$249K0.0%0.326%1.19%
12CHARLES SCHWAB INVESTMENT MANAGEMENT INC31K$245K-1.8%0.321%0.00%
13AMERICAN CENTURY COMPANIES INC28K$223K-54.6%0.292%0.00%
14XTX Topco Ltd21K$164K—0.214%0.00%
15GOLDMAN SACHS GROUP INC15K$120K—0.157%0.00%
16NORTHERN TRUST CORP15K$116K0.0%0.152%0.00%
17Invesco Ltd.13K$102K-10.8%0.134%0.00%
18MORGAN STANLEY12K$96K-44.1%0.125%0.00%
19RAFFA WEALTH MANAGEMENT, LLC2$49K—0.000%0.00%
20SIMPLEX TRADING, LLC5K$36K+49.8%0.048%0.00%
21SBI Securities Co., Ltd.4K$33K+20.1%0.043%0.00%
22GROUP ONE TRADING LLC4K$29K+350.7%0.038%0.00%
23JPMORGAN CHASE & CO4K$28K—0.037%0.00%
24Vanguard Global Advisers, LLC2K$16K0.0%0.020%0.00%
25FMR LLC2K$12K-12.8%0.016%0.00%

denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in MCRB — a direct measure of their conviction.

$28K
  • Continuum Advisory, LLC$371
  • Larson Financial Group LLC$39
  • WHITTIER TRUST CO OF NEVADA INC$8
  • 35.76%
    2.83 pp
    $43M
    21%
    Q4 20246910%38.59%161.40 pp$55M82%
    Q3 202477—199.99%—$296M—

    Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.

    6 institutions opened new positions in MCRB during Q2 2026, while 6 fully exited. 5 added to existing positions and 23 trimmed.

    How is institutional ownership of MCRB changing?

    MCRB institutional ownership fell by 2.71 percentage points quarter-over-quarter, with a net change of +1 holders.

    How concentrated is MCRB ownership among the top holders?

    The top 10 institutions account for 91.8% of all reported 13F value in MCRB, and the top 25 account for 99.9%.

    Where does this MCRB institutional ownership data come from?

    All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.

    MCRBSeres Therapeutics, Inc.
    $1.98$19M
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