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NBIXNeurocrine Biosciences, Inc.
$164.63$16.6B
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HomeStocksNBIXFinancials

Neurocrine Biosciences, Inc. (NBIX) Income Statement

30Y historyFree accessUpdated daily

Revenue and operating margin have improved strongly, with quarterly revenue reaching $1.1B and operating margin rising to 29.5% in 2026Q3, although the trend has been volatile, with margin dipping to 4.1% in 2025Q1.

Income StatementBalance SheetCash FlowRatios

NBIX Income Statement

Annual statement

NBIX Income Statement

Neurocrine Biosciences, Inc. (NBIX) annual income statement — 30-year revenue, gross profit & net income history

AnnualQuarterly
MetricTTMDec'25Dec'24Dec'23Dec'22Dec'21Dec'20Dec'19Dec'18Dec'17Dec'16Dec'15Dec'14Dec'13Dec'12Dec'11Dec'10Dec'09Dec'08Dec'07Dec'06Dec'05Dec'04Dec'03Dec'02Dec'01Dec'00Dec'99Dec'98Dec'97Dec'96
Sales/Revenue3.7B2.86B2.36B1.89B1.49B1.13B1.05B788.1M451.2M161.63M15M19.77M02.92M53.14M77.41M33.5M2.95M3.98M1.22M39.23M123.89M85.18M139.08M18.05M41.24M14.59M16.8M16M26.1M19.2M
Revenue Growth %37.98%21.45%24.81%26.76%31.34%8.38%32.71%74.67%179.16%977.51%-24.12%--100%-94.51%-31.36%131.08%1034.47%-25.71%224.75%-96.88%-68.33%45.45%-38.76%670.73%-56.25%182.71%-13.17%5%-38.7%35.94%-
Cost of Goods Sold81.2M52.1M34M39.7M23.2M14.3M10.1M7.4M4.9M1.25M0014.4M0000000000000-2.2M-2.1M-1.7M-1.3M-1M
COGS % of Revenue-1.82%1.44%2.1%1.56%1.26%0.97%0.94%1.09%0.78%-----------------15.07%-12.5%-10.63%-4.98%-5.21%
Gross Profit3.62B2.81B2.32B1.85B1.47B1.12B1.04B780.7M446.3M160.37M15M19.77M-14.4M0077.41M33.5M2.95M3.98M000000016.79M18.9M17.7M27.4M20.2M
Gross Margin %97.81%98.18%98.56%97.9%98.44%98.74%99.03%99.06%98.91%99.22%100%100%---100%100%100%100%-------115.07%112.5%110.63%104.98%105.21%
Gross Profit Growth %-20.98%25.65%26.06%30.94%8.05%32.68%74.93%178.29%969.15%-24.12%237.28%---100%131.08%1034.47%-25.71%--------100%-11.19%6.78%-35.4%35.64%-
Operating Expenses2.74B2.19B1.75B1.6B1.22B1.02B872.8M708.4M409.5M291.73M162.37M113.97M64.41M52.6M51.69M43.49M47.22M56.62M91.27M213.47M152.55M148.96M137.51M197.87M121.66M85.12M52.39M38.8M30.1M26.9M17.3M
OpEx % of Revenue-76.54%74.33%84.6%81.72%89.7%83.45%89.89%90.76%180.5%1082.48%576.51%-1801.88%97.28%56.18%140.96%1917.47%2296.18%17440.03%388.82%120.24%161.44%142.27%674.2%206.4%359.11%230.95%188.13%103.07%90.1%
Selling, General & Admin1.43B1.16B1.01B887.6M752.7M583.3M433.3M354.1M248.93M169.91M68.08M32.48M17.99M13.35M13.44M12.46M16.07M14.83M20.24M37.48M54.87M42.33M22.44M20.59M12.72M10.86M9.96M7.5M6.6M5.7M3.7M
SG&A % of Revenue-40.42%42.76%47.04%50.56%51.46%41.43%44.93%55.17%105.12%453.87%164.3%-457.31%25.29%16.09%47.97%502.17%509.18%3062.17%139.86%34.17%26.35%14.81%70.5%26.33%68.29%44.64%41.25%21.84%19.27%
Research & Development1.23B1.02B731.1M565M463.8M328.1M275M200M155.8M91.83M94.29M81.49M46.42M39.25M37.16M30.95M31.15M33.72M55.54M81.98M97.68M106.63M115.07M177.27M108.94M74.27M40.23M29.2M21.8M19.9M12.6M
R&D % of Revenue-35.51%31.04%29.94%31.15%28.95%26.29%25.38%34.53%56.81%628.61%412.22%-1344.57%69.93%39.98%92.99%1141.96%1397.33%6698.12%248.96%86.07%135.09%127.46%603.71%180.08%275.75%173.81%136.25%76.25%65.63%
Other Operating Expenses3M17.4M12.5M143.9M0105.3M164.5M154.3M4.8M30M0018K01.09M82K2.8M2.56M2.05M94M0000002.2M2.1M1.7M1.3M1M
Operating Income881.2M619.1M570.5M250.9M249M102.5M163M72.3M36.8M-131.36M-147.37M-94.2M-64.41M-49.68M1.45M33.92M-13.72M-53.67M-87.3M-212.24M-113.32M-25.07M-52.33M-58.79M-103.61M-43.88M-35.6M-19.9M-12.4M500K2.9M
Operating Margin %23.81%21.64%24.22%13.3%16.73%9.04%15.58%9.17%8.16%-81.27%-982.48%-476.51%--1701.88%2.72%43.82%-40.96%-1817.47%-2196.18%-17340.03%-288.82%-20.24%-61.44%-42.27%-574.2%-106.4%-244.04%-118.45%-77.5%1.92%15.1%
Operating Income Growth %-8.52%127.38%0.76%142.93%-37.12%125.45%96.47%128.01%10.86%-56.44%-46.25%-29.66%-3530.8%-95.73%347.21%74.43%38.52%58.87%-87.3%-351.97%52.09%10.98%43.26%-136.12%-23.26%-78.9%-60.48%-2580%-82.76%-
EBITDA964.8M649.2M597.6M272.2M264.6M113.4M171.6M79.7M40.8M-128.96M-145.92M-93.19M-63.58M-49.01M2.1M34.62M-12.29M-50.49M-79.69M-202.84M-102.75M-14.98M-45.25M-55.09M-100.52M-41.23M-33.4M-17.8M-10.7M1.8M3.9M
EBITDA Margin %26.06%22.7%25.37%14.42%17.77%10%16.41%10.11%9.04%-79.79%-972.79%-471.41%--1678.9%3.96%44.72%-36.67%-1709.82%-2004.73%-16571.73%-261.89%-12.09%-53.13%-39.61%-557.04%-99.97%-228.98%-105.95%-66.88%6.9%20.31%
EBITDA Growth %66.37%8.63%119.54%2.87%133.33%-33.92%115.31%95.34%131.64%11.62%-56.58%-46.57%-29.74%-2428.12%-93.92%381.75%75.67%36.64%60.71%-97.41%-586.01%66.9%17.86%45.19%-143.79%-23.43%-87.66%-66.36%-694.44%-53.85%-
D&A (Non-Cash Add-back)83.6M30.1M27.1M21.3M15.6M10.9M8.6M7.4M4M2.4M1.45M1.01M827K671K657K694K1.44M3.18M7.61M9.4M10.57M10.09M7.08M3.69M3.1M2.65M2.2M2.1M1.7M1.3M1M
EBIT863M636.5M612.6M394.8M221M127.2M139.5M78.5M52.3M-123.02M-141.09M-88.93M-64.41M-49.68M1.45M33.92M-13.72M-51.11M-81.59M-212.24M-113.32M-25.07M-52.33M-58.79M-103.61M-43.88M-35.6M-19.9M-12.4M500K2.9M
Net Interest Income-17.9M90.3M-35.6M-4.6M4.1M-25.8M-32.8M-32M-30.5M-19.52M2.84M1.93M0400K489K435K397K691K-7.03M000000000000
Interest Income-14.7M90.3M91M011.2M000002.84M1.93M629K400K489K435K397K691K0000000000000
Interest Expense3.2M0126.6M4.6M7.1M25.8M32.8M32M30.53M19.52M000000007.03M000000000000
Other Income/Expense50.9M86.3M-84.5M81.2M-35.1M-1.1M-56.3M-25.8M-15.05M-11.18M6.28M5.27M3.87M3.59M3.58M3.65M5.75M2.63M-1.31M4.94M6.11M2.88M6.64M28.69M9.08M7.09M7.09M200K-7.4M4.8M3.2M
Pretax Income932.1M705.4M486M332.1M213.9M101.4M106.7M46.5M21.84M-142.54M-141.09M-88.93M-60.54M-46.09M5.03M37.57M-7.97M-88.61M-88.61M-207.3M-107.2M-22.19M-45.69M-30.1M-94.54M-36.79M-28.51M-19.7M-19.8M5.3M6.1M
Pretax Margin %25.18%24.66%20.63%17.6%14.37%8.95%10.2%5.9%4.84%-88.19%-940.6%-449.84%--1578.97%9.46%48.53%-23.78%-3000.78%-2229.26%-16936.19%-273.25%-17.91%-53.65%-21.64%-523.89%-89.21%-195.41%-117.26%-123.75%20.31%31.77%
Income Tax229.6M226.8M144.7M82.4M59.4M11.8M-300.6M9.5M730K00000000173K000079K158K0120K302K-3.1M7.6M200K200K
Effective Tax Rate %24.63%32.15%29.77%24.81%27.77%11.64%-281.72%20.43%3.34%0%0%0%0%0%0%0%0%-0.2%0%0%0%0%-0.17%-0.52%0%-0.33%-1.06%15.74%-38.38%3.77%3.28%
Net Income702.5M478.6M341.3M249.7M154.5M89.6M407.3M37M21.11M-142.54M-141.09M-88.93M-60.54M-46.09M5.03M37.57M-7.97M-51.04M-88.61M-207.3M-107.2M-22.19M-45.77M-30.26M-94.54M-36.91M-28.81M-16.8M-20M5.1M5.9M
Net Margin %18.98%16.73%14.49%13.23%10.38%7.9%38.94%4.69%4.68%-88.19%-940.6%-449.84%--1578.97%9.46%48.53%-23.78%-1728.34%-2229.26%-16936.19%-273.25%-17.91%-53.74%-21.75%-523.89%-89.5%-197.48%-100%-125%19.54%30.73%
Net Income Growth %64.14%40.23%36.68%61.62%72.43%-78%1000.81%75.26%114.81%-1.03%-58.65%-46.89%-31.36%-1017.21%-86.63%571.52%84.39%42.4%57.25%-93.37%-383.1%51.52%-51.29%68%-156.13%-28.12%-71.48%16%-492.16%-13.56%-
Net Income (Continuing)702.5M478.6M341.3M249.7M154.5M89.6M407.3M37M21.11M-142.54M-141.09M-88.93M-60.54M-46.09M5.03M37.57M-7.97M-51.04M-88.61M-207.3M-107.2M-22.19M-45.77M-30.26M-94.54M-36.91M-28.81M-16.8M-20M5.1M5.9M
Discontinued Operations0000000000000000000000000000000
Minority Interest0000000000000000000000000000000
EPS (Diluted)6.684.673.292.471.560.924.160.390.22-1.62-1.63-1.05-0.81-0.690.080.67-0.15-1.30-2.30-5.45-2.84-0.58-1.26-0.93-3.10-1.42-1.30-0.88-1.100.280.36
EPS Growth %61.24%41.95%33.2%58.33%69.57%-77.88%966.67%77.27%113.58%0.61%-55.24%-29.63%-17.39%-1018.77%-88.79%546.67%88.46%43.48%57.8%-91.9%-389.66%53.97%-35.48%70%-118.31%-9.23%-47.73%20%-492.86%-22.22%-
EPS (Basic)-4.813.402.561.610.954.370.400.22-1.62-1.63-1.05-0.81-0.690.080.68-0.15-1.30-2.30-5.45-2.84-0.60-1.26-0.93-3.10-1.42-1.30-0.88-1.100.300.39
Diluted Shares Outstanding105.2M102.5M103.7M101M98.9M97.9M97.8M95.73M95.4M88.09M86.71M84.5M74.58M66.99M66.95M56.35M52.82M39.14M38.45M38.01M37.72M37.99M36.2M32.37M30.49M26.03M22.12M19.07M18.14M18.21M16.39M
Basic Shares Outstanding101.6M99.5M100.4M97.7M95.8M94.6M93.1M91.63M95.4M87.99M86.56M84.5M74.58M66.8M65.62M55.18M52.82M39.14M38.45M38.01M37.72M36.76M36.2M32.37M30.49M26.03M22.12M19.07M18.14M17M15.13M
Dividend Payout Ratio-------------------------------

Key Metrics

Growth RegimeExpanding
ProfitabilityStrong
Balance SheetMixed
Cash FlowStable
Top Statement Risk

Quarterly operating margin volatility

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q3)

Revenue Growth Sustained at Double Digits

Based on reported quarterly figures, NBIX revenue rose 41.2% year over year to $1.1B in 2026Q3, following 39.5% growth in Q2, suggesting the commercial expansion has durable momentum rather than a single-quarter spike.

The jump from roughly $622M in 2024Q3 to $1.1B in 2026Q3 indicates a sustained compounding trajectory rather than a one-time catalyst. Investors should monitor whether the growth rate can hold above 30% as the comparison base becomes more demanding in the coming periods. The lumpiness between quarters, such as the 2025Q1 slowdown to 11.1%, suggests revenue timing remains sensitive to product launch cadence and reporting periods.

Gross Margin Near-Saturation Constrains Upside

As reported in financial statements, NBIX gross margin has held between 97.6% and 98.7% across the ten quarters, leaving limited room for further expansion and making operating margin the more meaningful profitability lever.

Gross margins at this level reflect a high-value, low-cost-of-goods product profile typical of specialty pharmaceuticals, so the margin itself is not a differentiator within the period. The quarterly erosion in gross margin toward 97.6% in 2026Q2 and 2026Q3 is modest but may warrant monitoring for early signs of pricing or mix pressure. The analytical focus should therefore shift to how efficiently revenue converts into operating income.

Operating Leverage Visible but Uneven

Based on NBIX's reported figures, operating margin moved from 22.6% in 2024Q4 to 29.5% in 2026Q3, indicating that operating income has generally scaled faster than revenue, although the trend is not linear.

The 2026Q2 operating margin contraction to 15.8% despite 39.5% revenue growth shows SG&A rising to $439.7M and overwhelming the gross profit gain. This pattern suggests overhead efficiency depends heavily on commercial spending timing rather than on steady structural improvement. Investors may wish to examine whether SG&A intensity normalizes or continues to swing with launch activity.

Net Income Diverges from Operating Trends

As reported in financial statements, NBIX's 2026Q1 net income of $197.9M exceeded its operating income of $186.0M, and 2025Q1 net income of $7.9M sat far below operating income of $23.6M, indicating non-operating items materially affect reported earnings.

The gap between operating and net income in several quarters suggests tax effects, interest income, or other non-operating items play a meaningful role in reported EPS. The 2025Q1 EPS of $0.08 versus 2025Q3 EPS of $2.04 illustrates how sensitive per-share results are to these items. Stock-based compensation of roughly $41M to $66M per quarter should also be considered when assessing the underlying earnings base.

Peer-Relative Margin Gap Warrants Scrutiny

Based on peer context, NBIX's 2026Q3 operating margin of 29.5% trails the 49.5% reported by PTCT and the 38.5% reported by INVA, which may suggest the company's cost base is heavier than some specialty biotech comparables.

A bear case would emphasize that SG&A of $366M to $440M per quarter absorbs a large share of revenue and could pressure margins if competitive launches intensify. The quarterly volatility in operating margin, ranging from 4.1% to 30.1% over the period, may indicate that earnings are less durable than the headline revenue growth implies. These observations are analytical inferences from reported figures and warrant further investigation into the drivers of cost intensity.

NBIX — Frequently Asked Questions

Quick answers to the most common questions about buying NBIX stock.

What was Neurocrine Biosciences, Inc.'s (NBIX) revenue in 2025?

For fiscal year 2025, Neurocrine Biosciences, Inc. (NBIX) reported total revenue of $2.86B. This represents a 14798.4% increase compared to $19.2M in 1996.

Is Neurocrine Biosciences, Inc. (NBIX) profitable?

Neurocrine Biosciences, Inc. (NBIX) is profitable, generating $478.6M in net income for the fiscal year ending 2025 with a net profit margin of 16.7%.

What is Neurocrine Biosciences, Inc.'s operating profit margin?

Neurocrine Biosciences, Inc. (NBIX) reported an operating income of $619.1M, resulting in an operating profit margin of 21.6%. This margin reflects the operational efficiency of the business before interest and taxes.

What is Neurocrine Biosciences, Inc.'s gross profit and gross margin?

Neurocrine Biosciences, Inc. (NBIX) generated $2.81B in gross profit for the year, representing a gross profit margin of 98.2%. This demonstrates the company's core pricing power and production efficiency.