Latest Ratios: P/E Ratio -49.3x · EV/EBITDA N/A · ROE N/A. (2011–2025 historical series)
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $1.4B | $1.1B | $136M | $269M | $128M | $281M | $402M | — | — | — | — |
| Enterprise Value | $1.5B | $1.1B | $137M | $244M | $140M | $243M | $332M | — | — | — | — |
| P/E Ratio → | -49.25 | — | — | — | — | — | — | — | — | — | — |
| P/S Ratio | 42.03 | 37.30 | — | 7.42 | 26.78 | 106.29 | 173.06 | — | — | — | — |
| P/B Ratio | — | — | — | — | — | 10.50 | 5.71 | — | — | — | — |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | — | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 38.73 | — | 6.74 | 29.25 | 91.97 | 142.88 | — | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| Operating Margin | -36.5% | -36.5% | 951.2% | -74.0% | -977.8% | -1986.4% | -1566.8% | -1841.0% | -864.2% | -678.9% | -403.1% |
| Net Profit Margin | -80.8% | -80.8% | 947.6% | -109.6% | -1194.3% | -1775.7% | -1444.7% | -2003.7% | -872.2% | -702.4% | -403.6% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | — | — | — | — | — | -96.7% | -98.0% | -825.6% | -104.3% | -85.3% | -132.6% |
| ROA | -35.5% | -35.5% | -84.5% | -51.7% | -70.6% | -39.9% | -35.3% | -99.4% | -58.5% | -59.5% | -77.0% |
| ROIC | — | — | — | — | — | — | -698.8% | -1153.3% | — | -1099.7% | -628.4% |
| ROCE | -115.5% | -115.5% | -260.5% | -81.3% | -107.7% | -58.4% | -46.5% | -122.4% | -72.7% | -71.9% | -105.4% |
Solvency and debt-coverage ratios — lower is generally safer
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | — | — | — | — | 1.72 | 0.70 | — | 1.44 | 0.11 | 0.33 |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | — | — | — | — | -1.41 | -1.00 | — | -1.10 | -0.97 | -0.88 |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | — | — | — | — | — | — |
| Interest Coverage | -1.30 | -1.30 | -8.44 | -3.04 | -7.83 | -67.43 | -109.96 | -9.76 | -35.50 | -233.15 | -213.84 |
Short-term solvency ratios and asset-utilisation metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.09 | 1.09 | 1.04 | 1.75 | 1.38 | 2.53 | 6.58 | 3.22 | 3.68 | 5.68 | 3.26 |
| Quick Ratio | 1.09 | 1.09 | 1.04 | 1.75 | 1.30 | 2.53 | 6.58 | 3.03 | 3.58 | 6.20 | 3.87 |
| Cash Ratio | 0.92 | 0.92 | 0.84 | 1.51 | 1.09 | 2.28 | 6.26 | 2.45 | 3.12 | 5.05 | 2.55 |
| Asset Turnover | — | 0.44 | -0.11 | 0.39 | 0.08 | 0.03 | 0.02 | 0.05 | 0.08 | 0.06 | 0.18 |
| Inventory Turnover | — | — | — | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | 94.57 | -433.28 | 29.91 | 217.20 | 537.02 | 608.36 | 180.42 | 104.60 | 82.77 | 0.35 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — | — | — |
| Shares Outstanding | — | $48M | $47M | $37M | $35M | $35M | $24M | $22M | $20M | $17M | $15M |
Includes 30+ ratios · 15 years · Updated daily
Live VCP patterns, Cup & Handle overlays, support/resistance, and AI trade plans.
High-probability breakout stocks crossing their pivot across 5 pattern engines.
DCF models, multiple analysis, and analyst estimates.
10-year return with dividends reinvested.
Compare growth, multiples, and margins vs sector.
Quick answers to the most common questions about buying NBTX stock.
Nanobiotix S.A.'s current P/E ratio is -49.3x. This places it at the 50th percentile of its historical range.
Based on historical data, Nanobiotix S.A. is trading at a P/E of -49.3x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
Nanobiotix S.A. has 100.0% gross margin and -36.5% operating margin.
Key Metrics
Top Statement Risk
Negative equity with accelerating burn
Premium Multiple on Unstable Revenue Base
Nanobiotix trades at a trailing price-to-sales ratio of 47.42 and a negative trailing P/E of -55.56, per the supplied valuation data — multiples that appear extreme when set against loss-making medtech peers such as Novocure (P/E -12.98) and Accuray (P/E -19.34).
The 47.42x price-to-sales multiple is only defensible if the market is capitalizing a revenue stream that is contract-driven and historically reversible: the prior income statement analysis shows quarterly revenue swinging from positive $32.9M in 2023Q4 to negative $16.5M in 2024Q4, which makes any sales-based multiple mechanically unstable. Because every reported operating margin sits near or below zero (from -19.5% in 2022Q2 to -5.4% in 2026Q2), the negative trailing P/E offers no anchor, and investors should treat the headline multiples as reflecting pipeline optionality rather than earnings capacity. Forward P/E, EV/EBITDA and PEG are unavailable, so the usual growth-adjusted cross-checks on this valuation cannot be performed with the supplied data.
Gross Margin Uninformative as Losses Persist
As reported in Nanobiotix's quarterly filings, ROA deteriorated to -35.5% in 2026Q2 and the net margin widened to -9.4% from -6.2% in 2025Q4, despite the operating margin remaining nominally negative at just -5.4% and gross margin stuck at 100.0%.
The 100% gross margin is not evidence of pricing power: with zero COGS across all reported periods, it reflects licensing-type receipts rather than product economics, so gross margin carries no analytical signal about true earning power here. The more informative read is the persistent gap between operating and net margins — the 2026Q2 net loss exceeded the operating loss by roughly $14.6M, a pattern recurring in 2022Q4 and 2023Q4 — indicating that below-the-line items, rather than operations alone, are driving reported profitability. Combined with an operating margin that swung from +3.0% in 2025Q2 to -5.4% in 2026Q2, the margin trajectory suggests that the company has not yet found a stable earning-power floor, and reported margins may understate the true cost of the current model.
Debt Growth Outpacing Earning Capacity
Interest coverage stood at -1.36 in 2026Q2 versus -2.13 in 2025Q4, according to Nanobiotix's reported ratio data, while the one readable D/EBITDA reading of 47.27 in 2025Q2 signals that EBITDA is too small to carry the existing debt load meaningfully.
Placed against the balance sheet findings — total debt of $106.6M against equity of -$33.4M — the negative coverage ratios imply that operating earnings are insufficient to service interest, a position that appears to depend on refinancing or additional equity issuance rather than internal cash generation. The negative coverage ratio is nonetheless directionally improving (from -7.54 in 2023Q2 to -1.36 in 2026Q2), but this improvement looks more like the arithmetic effect of shrinking interest or asset base than a strengthening debt-service profile. Debt-to-equity is unavailable in the recent quarters, so the extent to which leverage has structurally worsened cannot be fully confirmed from the ratio table alone, and covenant or refinancing risk warrants monitoring in the absence of disclosed terms.
Asset Turnover Near Zero on Deferred Revenue
Asset turnover fell to 0.04 in 2026Q2 versus 0.47 in 2025Q2, per the company's reported ratio data, while DSO stretched to 211 days — both readings consistent with a business whose balance sheet is dominated by deferred collaboration income rather than operating assets.
A near-zero asset turnover on a balance sheet where deferred revenue of $36.2M represents roughly 27% of total assets suggests that the asset base is largely contract-accounting driven rather than commercially productive, which distorts any efficiency read-through to operations. The DSO volatility — from 18 days in 2025Q2 to 211 days in 2026Q2 — most likely reflects the timing of large lumpy collections rather than a genuine deterioration in customer payment discipline, though the direction is unhelpful when working capital consumed $4.4M in 2026Q2, the largest drag in the series. Cash conversion cycle cannot be computed because DIO and DPO are unavailable, so the overall working-capital position should be inferred from cash burn behavior rather than cycle metrics.
P/S Multiple Misleads in Pre-Revenue Models
The most commonly misapplied ratio for Nanobiotix is the price-to-sales multiple of 47.42, which capitalizes revenue that prior analysis shows is lumpy and reversible — swinging to negative $16.5M in 2024Q4 — and therefore obscures the company's real metric: cash runway against burn.
For a pre-commercial biotech whose sales derive from collaboration accounting with zero COGS and a single reversal quarter that wiped out revenue, price-to-sales treats unstable, non-recurring receipts as a sustainable annuity; the same criticism applies to gross margin (100%), which says nothing about unit economics. The more decision-useful metrics are cash runway versus operating burn — cash of $110.8M against quarterly operating outflow of about $22.3M implies roughly five quarters of liquidity — and the deferred revenue balance, which represents contracted income that may or may not convert into repeatable product revenue. Analysts should therefore weight free cash flow margin (-6.2% in 2026Q2) and cash conversion far more heavily than sales multiples, and treat current ratio of 1.44 as insufficient evidence of structural strength given the burn trajectory.