Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in NGNE held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Samsara BioCapital, LLC | 1.7M | $34.6M | 0.0% | 10.867% | 3.36% |
| 2 | Redmile Group, LLC | 1.5M | $29.4M | 0.0% | 9.237% | 1.95% |
| 3 | Casdin Capital, LLC | 1.4M | $28.6M | +9.7% | 8.989% | 2.17% |
| 4 | RTW INVESTMENTS, LP | 1.4M | $27.5M | 0.0% | 8.622% | 0.27% |
| 5 | EcoR1 Capital, LLC | 1.3M | $25.6M | 0.0% | 8.046% | 1.09% |
| 6 | BlackRock, Inc. | 1.0M | $20.3M | +6.3% | 6.360% | 0.00% |
| 7 | BAKER BROS. ADVISORS LP | 992K | $20.0M | 0.0% | 6.276% | 0.11% |
| 8 | Trails Edge Capital Partners, LP | 783K | $15.8M | -0.3% | 4.954% | 3.62% |
| 9 | BALYASNY ASSET MANAGEMENT LLC | 718K | $14.5M | +18.0% | 4.546% | 0.05% |
| 10 | TORONTO DOMINION BANK | 681K | $13.7M | 0.0% | 4.312% | 0.02% |
| 11 | JENNISON ASSOCIATES LLC | 528K | $10.6M | -1.0% | 3.339% | 0.01% |
| 12 | ArrowMark Colorado Holdings LLC | 525K | $10.6M | -9.1% | 3.321% | 0.28% |
| 13 | VANGUARD CAPITAL MANAGEMENT LLC | 515K | $10.4M | — | 3.257% | 0.00% |
| 14 | GREAT POINT PARTNERS LLC | 500K | $10.1M | +42.9% | 3.164% | 2.47% |
| 15 | CITADEL ADVISORS LLC | 413K | $8.3M | +13.5% | 2.615% | 0.00% |
| 16 | FMR LLC | 383K | $7.7M | +193.6% | 2.421% | 0.00% |
| 17 | STATE STREET CORP | 313K | $6.3M | +1.7% | 1.981% | 0.00% |
| 18 | MORGAN STANLEY | 285K | $5.8M | -23.2% | 1.805% | 0.00% |
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 279K | $5.6M | +11.7% | 1.766% | 0.00% |
| 20 | MILLENNIUM MANAGEMENT LLC | 205K | $4.1M | +187.2% | 1.296% | 0.00% |
| 21 | UBS Group AG | 186K | $3.7M | +20.5% | 1.175% | 0.00% |
| 22 | BLAIR WILLIAM & CO/IL | 168K | $3.4M | +2.8% | 1.065% | 0.01% |
| 23 | GOLDMAN SACHS GROUP INC | 108K | $2.2M | -33.5% | 0.682% | 0.00% |
| 24 | DEUTSCHE BANK AG\ | 106K | $2.1M | +24.2% | 0.672% | 0.00% |
| 25 | Rock Springs Capital Management LP | 104K | $2.1M | 0.0% | 0.660% | 0.12% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in NGNE — a direct measure of their conviction.
Filings activity in NGNE during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 94 | +1.1% | 74.21% | +0.20 pp | $341M | +0.3% |
| Q4 2025 | 93 | +6.9% | 74.01% | +16.35 pp | $340M | +28% |
| Q3 2025 | 87 | +4.8% | 57.66% | +7.36 pp | $265M | +15% |
| Q2 2025 | 83 | 2.4% | 50.30% | +5.60 pp | $231M | +13% |
| Q1 2025 | 85 | 4.5% | 44.70% | 35.56 pp | $206M | 44% |
| Q4 2024 | 89 | +2.3% | 80.26% | 45.90 pp | $369M | 36% |
| Q3 2024 | 87 | +30% | 126.16% | +21.24 pp | $580M | +20% |
| Q2 2024 | 67 | — | 104.92% | — | $482M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying NGNE stock.
Based on Q1 2026 13F filings, institutional ownership of Neurogene Inc. stands at 74.2%, held across 94 reporting institutions.
Samsara BioCapital, LLC is the largest reported institutional holder of NGNE, with approximately 1,717,127 shares worth $0.03B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of NGNE, including CITADEL ADVISORS LLC, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for NGNE is 55 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
18 institutions opened new positions in NGNE during Q1 2026, while 17 fully exited. 39 added to existing positions and 36 trimmed.
NGNE institutional ownership rose by 0.20 percentage points quarter-over-quarter, with a net change of +1 holders.
The top 10 institutions account for 67.4% of all reported 13F value in NGNE, and the top 25 account for 94.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Neurogene Inc. (NGNE) Institutional Ownership