Cash burn consistently exceeds reported losses, with an operating cash flow to net income ratio of 1.87 in 2026Q2, and free cash flow margins have deepened to -7.5% as working capital drains accelerate against a shrinking revenue base.
Nektar Therapeutics (NKTR) cash flow statement — 30-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 | Dec'98 | Dec'97 | Dec'96 |
|---|
| Cash from Operations | -233.79M | -208.51M | -175.71M | -192.61M | -304.01M | -412.66M | -313.29M | -328.68M | 718.21M | -80.41M | -117.02M | -73.08M | -142.01M | -38.53M | -129.76M | -113.74M | -55.87M | 39.74M | -145.78M | 146.3M | -92.72M | -78M | -78.14M | -76.2M | -74.97M | -50.77M | -35.74M | -15.33M | -19.22M | 4.98M | -5.8M |
| Operating CF Margin % | - | -377.52% | -178.52% | -213.72% | -330.25% | -404.94% | -204.88% | -286.76% | 60.19% | -26.13% | -70.74% | -31.67% | -70.75% | -25.87% | -159.82% | -159.12% | -35.13% | 55.25% | -161.65% | 53.59% | -42.58% | -61.77% | -68.38% | -71.71% | -79.05% | -65.54% | -69.23% | -37.08% | -88.2% | 30.64% | -84.06% |
| Operating CF Growth % | -107.6% | -18.67% | 8.77% | 36.64% | 26.33% | -31.72% | 4.68% | -145.76% | 993.15% | 31.28% | -60.12% | 48.54% | -268.59% | 70.31% | -14.08% | -103.58% | -240.59% | 127.26% | -199.64% | 257.8% | -18.87% | 0.18% | -2.55% | -1.64% | -47.66% | -42.06% | -133.09% | 20.23% | -486.08% | 185.84% | -9.43% |
| Net Income | -157.13M | -164.08M | -118.96M | -276.06M | -368.2M | -523.84M | -444.44M | -440.67M | 681.31M | -96.69M | -153.52M | -81.18M | -53.92M | -162.01M | -171.85M | -133.98M | -37.94M | -102.52M | -34.34M | -32.76M | -154.76M | -185.11M | -101.89M | -46.68M | -107.47M | -250.01M | -97.4M | -38.45M | -18.36M | -9.98M | -10M |
| Depreciation & Amortization | 129K | -4.49M | 4.39M | 7.82M | 13.03M | 14.15M | 14.18M | 13.16M | 10.87M | 14.74M | 15.35M | 12.86M | 12.93M | 14.28M | 14.51M | 14.95M | 16.55M | 14.88M | 22.49M | 28.15M | 32.63M | 26.23M | 19.19M | 18.42M | 18.97M | 40.38M | 10.12M | 7.25M | 3.6M | 2.44M | 1.2M |
| Stock-Based Compensation | 11.98M | 12.65M | 21.61M | 33.39M | 57.32M | 94.67M | 94.26M | 99.8M | 88.1M | 36.62M | 25.85M | 19.67M | 17.02M | 17.71M | 16.2M | 18.89M | 17.4M | 10.33M | 9.87M | 14.78M | 9.7K | 1.85M | 1.18M | 201K | 549K | 881K | 865K | 0 | 0 | 0 | 0 |
| Deferred Taxes | 0 | 0 | 0 | -140K | 2.71M | 8.02M | 20.35M | 0 | 0 | 15.08M | 0 | 1.58M | 0 | 0 | 1.68M | 133.98M | 12.58M | 0 | -79.44M | -13.8M | -2.14M | -1.85M | -1.18M | -201K | 1.55M | -881K | -865K | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -8.8M | -15.58M | -76.51M | 62.19M | -9.36M | 17.41M | -14.35M | -22.65M | -23.06M | -12.54M | -12.63M | 8.7M | -1.61M | 918K | 8.11M | -132.62M | 198K | -657K | -37.57M | 43.17M | 40.39M | 76.32M | 12.22M | -29.26M | 960K | 150.81M | 47.92M | 10.69M | 284K | 600K | 200K |
| Working Capital Changes | -79.97M | -37.02M | -6.24M | -19.8M | 492K | -23.08M | 16.71M | 21.69M | -39.01M | -37.62M | 7.93M | -34.7M | -116.42M | 90.58M | 1.61M | -14.96M | -64.66M | 117.71M | -26.79M | 106.75M | -8.85M | 4.56M | -7.66M | -18.68M | 10.47M | 8.04M | 3.62M | 5.17M | -4.75M | 11.92M | 2.8M |
| Change in Receivables | 0 | 0 | -3.04M | 4.78M | 16.51M | 12.4M | 1.91M | 6.41M | -25.5M | 10.66M | 4.27M | -16.34M | -1.38M | 3.58M | -867K | 20.16M | -20.3M | 6.03M | 10.48M | 24.32M | 0 | 6.02M | -6.03M | -2.33M | 1.73M | -4.24M | -964K | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 497K | 699K | -3.4M | -509K | -2.63M | -1.28M | -655K | 383K | 237K | 1.61M | 500K | 4.82M | -5.61M | -5.39M | -795K | 2.85M | 2.87M | 1.5M | 3.97M | -7.42M | -3.69M | -263.01M | -241.35M | -291.63M | -462.74M | 0 | 0 | 0 | 0 |
| Change in Payables | 10.61M | -625K | 2.67M | -2.88M | 3.1M | -11.69M | 2.38M | 12.97M | 971K | 2.07M | 518K | -412K | -6.36M | 6.2M | -122K | -3.38M | 4.27M | -8.05M | 6.18M | -3.15M | 0 | 10.33M | -683K | -12.98M | 2.77M | 2.26M | 4.48M | 0 | 0 | 0 | 0 |
| Cash from Investing | -844.4M | -1.2M | 142.57M | 139.56M | 365.83M | 202.78M | 496.21M | 206.89M | -1.38B | -28.81M | -82.4M | -14.34M | -37.57M | 49.91M | 113.02M | -111.95M | 16.71M | -149.03M | 274.65M | -32.66M | -116.88M | 32.4M | -88.91M | 4.07M | 40.32M | -77.04M | -299.75M | -82.44M | -6.5M | -84.71M | -3.8M |
| Capital Expenditures | -262K | -171K | -1.47M | -865K | -5.68M | -14.99M | -7.26M | -26.29M | -14.24M | -9.68M | -6.39M | -11.2M | -9.98M | -4.09M | -10.58M | -9.72M | -31.46M | -20.7M | -18.86M | -32.8M | -22.52M | -17.95M | -27.19M | -18.75M | -16.33M | -34.32M | -53.85M | -20.5M | -34.58M | -17.26M | -2.2M |
| CapEx % of Revenue | 0.48% | 0.31% | 1.49% | 0.96% | 6.17% | 14.71% | 4.75% | 22.93% | 1.19% | 3.14% | 3.86% | 4.85% | 4.97% | 2.75% | 13.03% | 13.6% | 19.78% | 28.78% | 20.91% | 12.01% | 10.35% | 14.22% | 23.8% | 17.64% | 17.21% | 44.3% | 104.3% | 49.57% | 158.68% | 106.23% | 31.88% |
| Acquisitions | 0 | -697K | 65.39M | 0 | 13.2M | -217.77M | -503.47M | 0 | 2.63M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -4M | 115M | 0 | 0 | -30.71M | -31.97M | 0 | 3.44M | -82.05M | -2.29M | -15.29M | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 18K | 0 | 0 | 1.25M | 0 | 217.77M | 503.47M | 0 | 2.63M | -19.13M | -76.01M | 25M | -27.59M | 54M | -25M | 0 | 0 | -440K | -169K | 0 | 0 | 0 | 31.97M | 92K | 39K | -14.8M | -1.23M | 10K | 0 | 0 | 100K |
| Cash from Financing | 1.07B | 180.57M | 42.12M | 30K | 1.51M | 36.24M | -80.35M | 23.36M | 851.97M | 54.39M | 203.62M | 130.78M | 152.98M | 2.22M | 26.8M | 222.34M | 7.54M | 3.54M | -49.74M | -101.77M | 11.77M | 274.85M | 207.41M | 101.3M | 38.72M | 22.61M | 438.07M | 106.29M | 36.53M | 76.11M | 24.4M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | -103.75M | 0 | 0 | -5.13M | -5.95M | 98.58M | -10.54M | -5.99M | -96.9M | -1.98M | -1.36M | -1.28M | -50.13M | -105.55M | -10.49M | 232.43M | -3.95M | 98.75M | -1.72M | 16.56M | 461.44M | 104.74M | -181K | 4.83M | -300K |
| Equity Issued (Net) | 1.08B | 180.57M | 27.12M | 30K | 758K | 33.24M | 23.4M | 0 | 790.23M | 0 | 189.28M | 32.21M | 116.54M | 0 | 0 | 219.78M | 8.89M | 4.82M | 384K | 3.78M | 22.26M | 42.42M | 211.36M | 2.55M | 40.44M | 6.05M | 17.32M | 1.54M | 36.72M | 71.28M | 24.6M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | -3M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -784K | 0 | 15M | 0 | 750K | 3M | 0 | 23.36M | 61.73M | 59.52M | 20.29M | 0 | 46.98M | 8.21M | 123.7M | 4.53M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -40.69M | 0 | 0 | 0 | 100K |
| Net Change in Cash | 15.21M | -29.14M | 8.97M | -52.95M | 63.01M | -173.74M | 102.59M | -98.54M | 190.14M | -54.88M | 4.07M | 43.2M | -26.7M | 13.63M | 10.13M | -2.44M | -31.84M | -105.99M | 79.29M | 12.53M | -197.51M | 229.21M | 40.36M | 29.17M | 4.07M | -105.2M | 102.58M | 8.51M | 10.81M | -3.62M | 14.8M |
| Free Cash Flow | -234.05M | -208.68M | -177.18M | -193.47M | -309.68M | -427.65M | -320.55M | -354.97M | 703.98M | -90.09M | -123.42M | -84.28M | -151.98M | -42.62M | -140.34M | -123.46M | -87.33M | 19.04M | -164.64M | 113.51M | -115.24M | -95.95M | -105.34M | -94.95M | -91.3M | -85.09M | -89.59M | -35.84M | -53.81M | -12.28M | -8M |
| FCF Margin % | -428.75% | -377.83% | -180.01% | -214.68% | -336.41% | -419.65% | -209.62% | -309.7% | 58.99% | -29.28% | -74.6% | -36.52% | -75.72% | -28.62% | -172.85% | -172.73% | -54.91% | 26.47% | -182.55% | 41.57% | -52.93% | -75.98% | -92.18% | -89.36% | -96.26% | -109.85% | -173.53% | -86.65% | -246.88% | -75.59% | -115.94% |
| FCF Growth % | -25.78% | -17.78% | 8.42% | 37.53% | 27.58% | -33.41% | 9.7% | -150.42% | 881.41% | 27% | -46.44% | 44.55% | -256.61% | 69.63% | -13.67% | -41.38% | -558.73% | 111.56% | -245.05% | 198.5% | -20.1% | 8.91% | -10.94% | -3.99% | -7.29% | 5.02% | -150.01% | 33.4% | -338.1% | -53.52% | -21.21% |
| FCF per Share | -7.08 | -12.37 | -12.92 | -15.27 | -24.82 | -35.00 | -26.92 | -30.43 | 58.63 | -8.67 | -13.26 | -9.54 | -17.97 | -5.52 | -18.33 | -16.40 | -13.92 | 3.08 | -26.72 | 18.53 | -19.25 | -16.75 | -20.14 | -25.51 | -24.77 | -24.02 | -32.00 | -15.80 | -25.67 | -6.68 | -5.28 |
| FCF Conversion (FCF/Net Income) | 1.49x | 1.27x | 1.48x | 0.70x | 0.83x | 0.79x | 0.70x | 0.75x | 1.05x | 0.83x | 0.76x | 0.90x | 2.63x | 0.24x | 0.76x | 0.85x | 1.47x | -0.39x | 4.25x | -4.47x | 0.60x | 0.42x | 0.77x | 1.63x | 0.70x | 0.20x | 0.37x | 0.40x | 1.05x | -0.50x | 0.58x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 9.74M | 19.2M | 19.47M | 20.12M | 20.59M | -20.23M | 17.45M | 17.59M | 9.62M | -10.28M | -10.6M | 11.22M | 14.7M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 76K | 2.66M | 272K | 325K | 539K | 555K | 618K | 556K | 757K | -860K | 964K | 1.01M | 1.02M | -957K | -407K | 743K | 812K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying NKTR stock.
Nektar Therapeutics (NKTR) generated $-208.5M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Nektar Therapeutics (NKTR) reported negative free cash flow of $208.7M in 2025, indicating capital requirements exceeded cash from operations.
Nektar Therapeutics (NKTR) spent $0.2M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Imminent liquidity crisis
Metrics are mathematically derived from official filings.
Cash Burn Exceeds Reported Losses
Operating cash flow consistently trails net income, with a 2026Q2 OCF/NI ratio of 1.87, indicating that the cash burn is significantly deeper than the accounting loss suggests, a trend that has persisted for over two years.
The persistent gap where operating cash outflows exceed net losses implies that non-cash charges like depreciation and stock-based compensation are not fully offsetting the cash consumed by operations. This pattern suggests the underlying business is consuming cash at a rate faster than the income statement alone would indicate, reinforcing the severity of the liquidity challenge.
FCF Margins Deepen in Contraction
Free cash flow margins have deteriorated from -2.2% in 2024Q1 to -7.5% in 2026Q2, with the trailing twelve-month FCF margin at -5.4%, demonstrating that the cash burn is accelerating relative to the shrinking revenue base.
The worsening FCF margin trend is particularly concerning because it occurs alongside a revenue collapse, meaning the company is failing to scale down its cost structure proportionally. This indicates that the fixed-cost R&D platform is not being adjusted quickly enough to match the new, lower-revenue reality, leading to a more severe cash drain per dollar of sales.
Working Capital Drains Accelerate
Working capital changes have been a significant source of cash outflow, with a -$46.6M drag in 2026Q2 and a cumulative -$146.0M outflow in 2025Q1 alone, suggesting aggressive management of receivables or payables that is consuming liquidity.
The large, negative working capital swings, particularly the -$68.0M in 2026Q1 and -$46.6M in 2026Q2, appear to be a major contributor to the operating cash flow deficit. This pattern may indicate that the company is collecting cash more slowly from partners or is accelerating payments to vendors, both of which would be red flags for a company with a dwindling cash balance.
Capital Preservation Mode with No Returns
Nektar has completely halted all shareholder returns, with zero dividends and buybacks for the past ten quarters, and its minimal capital expenditures of $112K in 2026Q2 underscore a focus on pure survival over investment.
The absence of any capital deployment to shareholders or for growth capex is a clear signal that all available cash is being directed toward funding operating losses and clinical trials. This posture is typical for a distressed biotech but confirms that the company is in a defensive, capital-preservation mode with no capacity for strategic investments or returns.
Cash Flow Obscures True Burn Rate
The reported operating cash flow may understate the true cash consumption because it includes non-cash collaboration revenue amortization, while the minimal capital expenditures mask the full cost of maintaining the R&D platform.
Analysts should scrutinize the operating cash flow line for non-cash items like the amortization of deferred revenue from legacy partnerships, which inflates OCF relative to actual cash receipts. Furthermore, the extremely low CapEx figures suggest that significant R&D costs, such as clinical trial site fees and third-party manufacturing, may be expensed directly rather than capitalized, potentially obscuring the true capital intensity of the ongoing programs.