Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in NKTR held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5.1M | $353.8M | +17.8% | 15.332% | 0.02% |
| 2 | Two Seas Capital LP | 3.1M | $215.9M | +57.8% | 9.355% | 4.28% |
| 3 | BlackRock, Inc. | 2.9M | $205.4M | +324.7% | 8.900% | 0.00% |
| 4 | BVF INC/IL | 2.4M | $166.9M | -6.6% | 7.234% | 4.27% |
| 5 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.5M | $104.5M | +65.8% | 4.529% | 0.01% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 1.5M | $104.5M | +25.0% | 4.528% | 0.00% |
| 7 | TWO SIGMA INVESTMENTS, LP | 1.2M | $83.9M | +29.1% | 3.636% | 0.06% |
| 8 | Vestal Point Capital, LP | 1.0M | $69.8M | +250.9% | 3.025% | 1.63% |
| 9 | MORGAN STANLEY | 937K | $65.4M | +42.0% | 2.833% | 0.00% |
| 10 | STATE STREET CORP | 910K | $63.5M | +271.7% | 2.752% | 0.00% |
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 881K | $61.5M | +154.1% | 2.666% | 0.00% |
| 12 | Prosight Management, LP | 810K | $56.5M | +10.2% | 2.450% | 9.74% |
| 13 | ARMISTICE CAPITAL, LLC | 724K | $50.5M | +25.3% | 2.190% | 0.62% |
| 14 | MILLENNIUM MANAGEMENT LLC | 648K | $45.2M | +60.3% | 1.961% | 0.02% |
| 15 | GILDER GAGNON HOWE & CO LLC | 601K | $41.9M | +121.1% | 1.818% | 0.43% |
| 16 | CITADEL ADVISORS LLC | 499K | $34.8M | -25.0% | 1.510% | 0.00% |
| 17 | BRAIDWELL LP | 474K | $33.1M | +112.7% | 1.433% | 1.22% |
| 18 | Sofinnova Investments, Inc. | 472K | $32.9M | -7.4% | 1.427% | 1.70% |
| 19 | Woodline Partners LP | 471K | $32.9M | +13.4% | 1.425% | 0.10% |
| 20 | ORBIMED ADVISORS LLC | 465K | $32.5M | +69.2% | 1.408% | 0.60% |
| 21 | UBS Group AG | 428K | $29.9M | +33.8% | 1.296% | 0.00% |
| 22 | EMERALD ADVISERS, LLC | 390K | $27.2M | -1.1% | 1.180% | 0.64% |
| 23 | VANGUARD PORTFOLIO MANAGEMENT LLC | 349K | $24.3M | +380.8% | 1.054% | 0.00% |
| 24 | DAFNA Capital Management LLC | 318K | $22.2M | +92.8% | 0.963% | 4.24% |
| 25 | NORTHERN TRUST CORP | 309K | $21.5M | +292.5% | 0.933% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in NKTR — a direct measure of their conviction.
Filings activity in NKTR during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new NKTR position in Q2 2026
Institutions that fully closed their NKTR position in Q2 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 247 | +12% | 115.24% | +16.72 pp | $2.62B | +32% |
| Q1 2026 | 220 | +19% | 98.52% | +4.46 pp | $1.98B | +158% |
| Q4 2025 | 185 | +22% | 94.06% | +9.29 pp | $769M | 15% |
| Q3 2025 | 152 | +38% | 84.77% | +57.48 pp | $909M | +315% |
| Q2 2025 | 110 | 30% | 27.29% | +4.07 pp | $219M | +180% |
| Q1 2025 | 157 | +9.0% | 23.22% | 1.85 pp | $78M | 32% |
| Q4 2024 | 144 | +3.6% | 25.07% | 0.50 pp | $116M | 30% |
| Q3 2024 | 139 | — | 25.57% | — | $165M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying NKTR stock.
Based on Q2 2026 13F filings, institutional ownership of Nektar Therapeutics stands at 115.2%, held across 247 reporting institutions.
FMR LLC is the largest reported institutional holder of NKTR, with approximately 5,067,920 shares worth $0.35B as of Q2 2026.
Yes — 4 widely-followed marquee investors appear among the top 25 institutional holders of NKTR, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, TWO SIGMA INVESTMENTS, LP, MILLENNIUM MANAGEMENT LLC, CITADEL ADVISORS LLC.
Our composite Smart Money Score for NKTR is 79 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
67 institutions opened new positions in NKTR during Q2 2026, while 40 fully exited. 99 added to existing positions and 74 trimmed.
NKTR institutional ownership rose by 16.72 percentage points quarter-over-quarter, with a net change of +27 holders.
The top 10 institutions account for 54.7% of all reported 13F value in NKTR, and the top 25 account for 75.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.