Despite historical cash-burning tendencies, Natera achieved positive free cash flow in seven of the last nine quarters, peaking at an 8.1% FCF margin in 2024Q3.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 |
|---|
| Cash from Operations | 211.02M | 215.3M | 135.66M | -246.96M | -431.5M | -335.24M | -182.51M | -63.44M | -70.58M | -97.83M | -74.05M | -37.83M | 10.49M | -24.13M | -14.9M |
| Operating CF Margin % | - | 9.34% | 7.99% | -22.81% | -52.61% | -53.6% | -46.68% | -20.99% | -27.39% | -46.38% | -34.11% | -19.87% | 6.59% | -43.74% | -104.6% |
| Operating CF Growth % | 886.46% | 58.7% | 154.93% | 42.77% | -28.72% | -83.68% | -187.67% | 10.11% | 27.85% | -32.1% | -95.74% | -460.65% | 143.47% | -61.91% | - |
| Net Income | -226.31M | -208.16M | -190.43M | -434.8M | -547.8M | -471.72M | -229.74M | -124.83M | -128.15M | -137.63M | -100.33M | -70.28M | -5.15M | -37.11M | -76.17M |
| Depreciation & Amortization | 54.47M | 43.48M | 30.97M | 24.1M | 16.7M | 11.25M | 8.61M | 7.73M | 7.5M | 7.14M | 6.18M | 5.54M | 5.15M | 2.53M | 723K |
| Stock-Based Compensation | 184M | 0 | 274.43M | 191.81M | 152.38M | 115.22M | 50.17M | 28.62M | 14.2M | 11.4M | 10.6M | 7.33M | 5.16M | 1.66M | 605K |
| Deferred Taxes | -60.8M | -60.8M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 215.05M | 369.93M | 18.55M | 19.89M | 30.36M | 55.61M | 27.58M | -2.17M | 8.72M | 1.65M | 7.16M | 10.23M | 1.91M | 10.56M | 60.54M |
| Working Capital Changes | 44.62M | 70.84M | 2.14M | -47.95M | -83.15M | -45.6M | -39.13M | 27.2M | 27.16M | 19.61M | 2.34M | 9.35M | 3.43M | -1.76M | -1.57M |
| Change in Receivables | -96.25M | 20.75M | -35.88M | -33.9M | -122.31M | -43.51M | -25.83M | 2.42M | -18.09M | 6.32M | -3.96M | -450K | 341K | -5.85M | -675K |
| Change in Inventory | -17.53M | -20.87M | -3.98M | -5.35M | -8.5M | -6.88M | -7.47M | 917K | -4.9M | -3.09M | -431K | 2.93M | -890K | -9.05M | -891K |
| Change in Payables | 20.25M | 753K | 13.21M | -15.46M | 5.46M | 19.22M | -118K | -6.26M | 3.78M | 217K | 1.26M | 1.35M | -2.43M | 6.79M | 0 |
| Cash from Investing | -147.53M | -132.21M | 137.62M | 168.5M | 330.34M | -205.19M | -331.46M | -266.35M | -5.16M | 13.78M | 47.03M | -210.68M | -9.94M | -8.24M | -4.59M |
| Capital Expenditures | -127.01M | -139.19M | -66.42M | -39.2M | -47.7M | -41.03M | -19.6M | -4.97M | -3.88M | -9.87M | -23.14M | -7.85M | -9.96M | -8.24M | -4.59M |
| CapEx % of Revenue | 5.08% | 6.04% | 3.91% | 3.62% | 5.82% | 6.56% | 5.01% | 1.64% | 1.51% | 4.68% | 10.66% | 4.12% | 6.25% | 14.94% | 32.19% |
| Acquisitions | -16.02M | -16.02M | 0 | 0 | 0 | 0 | 0 | 9.68M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -12.5M | 0 | -10.49M | 0 | 0 | -8.56M | 0 | 0 | 0 | 0 | 0 | 463K | 15K | 0 | 0 |
| Cash from Financing | 50.67M | 47.46M | 30.2M | 254.46M | 482.64M | 576.19M | 500.85M | 340.77M | 113.72M | 80.37M | 13.18M | 190.28M | 56.13M | 57.13M | 53K |
| Debt Issued (Net) | 0 | 0 | -82K | 0 | 30M | 0 | 199.56M | 0 | 0 | 75M | 7M | 9.03M | 2.63M | 25.23M | 0 |
| Equity Issued (Net) | 48.74M | 47.46M | 30.29M | 254.46M | 452.64M | 576.19M | 301.29M | 340.77M | 113.72M | 5.66M | 6.18M | 181.26M | 53.92M | 33.26M | 38K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -27K |
| Other Financing | 1.94M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -287K | 0 | -6K | -415K | -1.36M | 15K |
| Net Change in Cash | 114.16M | 130.55M | 303.49M | 176M | 381.48M | 35.76M | -13.13M | 10.98M | 37.98M | -3.67M | -13.84M | -58.23M | 56.68M | 24.75M | -19.44M |
| Free Cash Flow | 92.01M | 109.11M | 69.24M | -286.15M | -479.2M | -376.27M | -202.12M | -68.41M | -74.46M | -106.66M | -97.04M | -45.68M | 533K | -32.38M | -19.49M |
| FCF Margin % | 3.68% | 4.73% | 4.08% | -26.43% | -58.42% | -60.16% | -51.69% | -22.63% | -28.9% | -50.56% | -44.7% | -24% | 0.33% | -58.68% | -136.79% |
| FCF Growth % | 8% | 57.58% | 124.2% | 40.28% | -27.36% | -86.16% | -195.44% | 8.12% | 30.19% | -9.91% | -112.41% | -8671.11% | 101.65% | -66.1% | - |
| FCF per Share | 0.65 | 0.80 | 0.56 | -2.49 | -4.87 | -4.15 | -2.49 | -0.98 | -1.29 | -1.99 | -1.88 | -0.96 | 0.01 | -0.88 | -6.24 |
| FCF Conversion (FCF/Net Income) | -0.41x | -1.03x | -0.71x | 0.57x | 0.79x | 0.71x | 0.79x | 0.51x | 0.55x | 0.72x | 0.77x | 0.54x | -2.04x | 0.65x | 0.20x |
| Interest Paid | 1.04M | 0 | 7.9M | 11.35M | 8.06M | 7.08M | 3.3M | 12.46M | 7.91M | 3.57M | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 1.31M | 295K | 549K | 283K | 67K | 2.15M | 332K | 177K | 0 | 0 | 0 | 0 | 0 |
Reimbursement and litigation exposure
Based on Natera's reported figures, the persistent gap between net income and operating cash flow, highlighted by an OCF/NI ratio of -0.47 in 2026Q1, suggests that reported earnings remain heavily influenced by non-cash charges rather than reflecting the underlying cash-generative capacity of the core diagnostic business.
The consistent divergence between net losses and positive operating cash flow indicates that non-cash expenses, particularly stock-based compensation, are masking the true cash burn of the enterprise. Investors should monitor whether this disconnect narrows as the company scales, as the current reliance on non-cash adjustments to reach positive cash flow suggests that GAAP profitability remains a distant milestone.
As reported in financial statements, Natera has transitioned from a cash-burning entity in 2023Q4 to achieving positive free cash flow in seven of the last nine quarters, with a peak FCF margin of 8.1% in 2024Q3, signaling a potential shift toward self-sustaining operational growth.
The recent trend of positive free cash flow suggests that the company is successfully managing its high variable cost structure as it scales its oncology testing volume. However, the volatility in FCF margins warrants caution, as the company's ability to maintain these levels depends heavily on continued reimbursement stability and the containment of rising operating expenses.
According to recent SEC filings, Natera's capital expenditure as a percentage of revenue has remained relatively contained, fluctuating between 2.8% and 8.5% over the last ten quarters, which implies that the company is not currently facing an overwhelming burden of maintenance capital requirements.
The moderate capital intensity suggests that the company's laboratory infrastructure is sufficiently scalable to handle current volume growth without requiring massive, lumpy investments. This efficiency is critical for a high-growth diagnostics firm, as it allows a greater portion of operating cash flow to be directed toward R&D and commercial expansion rather than basic asset replacement.
Based on quarterly data, Natera's working capital changes have been highly erratic, swinging from a $40.9 million inflow in 2025Q3 to a $38.9 million outflow in 2023Q4, which suggests significant variability in the timing of insurance collections and the management of laboratory inventory levels.
The inconsistency in working capital movements likely reflects the complexities of the medical billing cycle and the inherent delays in securing reimbursement from diverse insurance payers. This volatility complicates cash flow forecasting and suggests that the company's cash position remains sensitive to the efficiency of its revenue cycle management processes.
As disclosed in quarterly financial data, the substantial scale of stock-based compensation, which reached $93.4 million in 2025Q2, acts as a significant non-cash add-back that obscures the true economic cost of talent acquisition and retention required to maintain the company's competitive position in the MRD market.
While these adjustments improve the appearance of operating cash flow, they represent a real dilution to shareholders that is not fully captured in standard cash flow metrics. Analysts should treat the reported operating cash flow with skepticism, as the reliance on equity-based incentives to manage cash burn may not be sustainable if market sentiment toward high-growth diagnostics shifts.
Quick answers to the most common questions about buying NTRA stock.
Natera, Inc. (NTRA) generated $215.3M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Natera, Inc. (NTRA) generated $109.1M in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Natera, Inc. (NTRA) spent $139.2M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.