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OBIOOrchestra BioMed Holdings, Inc.
$4.24$254M
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HomeStocksOBIOCash Flow

Orchestra BioMed Holdings, Inc. (OBIO) Cash Flow Statement

6Y historyFree accessUpdated daily

Operational cash flow remains structurally negative, with quarterly outflows frequently exceeding $13M and a notable $2.3M cash drain in 2025Q4 despite reported net income of $6.2M.

OBIO Cash Flow Statement

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly
MetricTTMDec'25Dec'24Dec'23Dec'22Dec'21Dec'20
Cash from Operations-54.52M-48.96M-50.56M-46.13M-29.29M-19.43M-26.18M
Operating CF Margin %--146.24%-1916.53%-1671.27%-829.01%2484.53%-459.11%
Operating CF Growth %-8.52%3.15%-9.61%-57.49%-50.75%25.8%-
Net Income-54.64M-52.7M-61.02M-49.12M-33.61M-23.01M-21.36M
Depreciation & Amortization334K327K308K287K222K181K137K
Stock-Based Compensation9.01M11.98M10.62M7.63M3.41M302K221K
Deferred Taxes00000288K0
Other Non-Cash Items3.82M1.8M308K-1.61M1.14M217K2.93M
Working Capital Changes-13.04M-10.37M-765K-3.31M-451K2.6M-8.12M
Change in Receivables5K-3K22K-3K25K47K-79K
Change in Inventory-142K-137K-28K131K-208K1K-26K
Change in Payables-3.06M02.97M145K01.08M-2.61M
Cash from Investing-29.62M-26.94M13.09M10.69M-64.12M13.02M26.97M
Capital Expenditures-561K-489K-289K-78K-591K-274K-539K
CapEx % of Revenue1.71%1.46%10.96%2.83%16.73%-35.04%9.45%
Acquisitions00-602K00-13.29M-27.5M
Investments-------
Other Investing0000013.29M27.5M
Cash from Financing94.16M88.33M29.17M46.22M103.26M-3.99M10M
Debt Issued (Net)17.91M17.91M15M-10.85M3.55M-4M10M
Equity Issued (Net)77.33M71.97M15.04M254K109.83M0162.29M
Dividends Paid0000000
Share Repurchases-428K000000
Other Financing-1.09M-1.55M-864K56.81M-10.13M7K-162.29M
Net Change in Cash10.02M12.43M-8.3M10.78M9.85M-10.4M10.78M
Free Cash Flow-55.08M-49.45M-50.85M-46.2M-29.88M-19.7M-26.72M
FCF Margin %-168.3%-147.7%-1927.48%-1674.09%-845.74%2519.57%-468.56%
FCF Growth %-1.14%2.74%-10.05%-54.64%-51.65%26.27%-
FCF per Share-1.43-1.29-1.38-1.39-1.17-0.96-1.31
FCF Conversion (FCF/Net Income)1.01x0.93x0.83x0.94x0.87x0.84x1.23x
Interest Paid00001.37M00
Taxes Paid0000000

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Milestone-dependent liquidity exhaustion

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Earnings Disconnect Masks Cash Burn

As reported in financial statements, the company exhibits a persistent divergence between net income and operating cash flow, with the 2025Q4 period showing a $6.2M profit that nonetheless resulted in a $2.3M cash outflow, highlighting the non-cash nature of recent milestone-driven accounting entries.

The consistent gap between net income and operating cash flow suggests that reported profitability is heavily influenced by accounting adjustments rather than actual cash generation. Investors should monitor this discrepancy closely, as it implies that the company's ability to fund operations remains entirely dependent on external capital rather than internal earnings.

Negative Free Cash Flow Persistence

Based on EDBL's reported figures, the company has maintained a consistent negative free cash flow trajectory, with quarterly outflows frequently exceeding $13M, underscoring the structural reliance on external financing to sustain the ongoing clinical development of the BackBeat Cardiac Neuromodulation Therapy platform.

The lack of a clear path toward positive free cash flow suggests that the company remains in a high-burn phase of its lifecycle. This trajectory warrants further investigation into the timing of future milestone payments, as any delay in clinical progress could rapidly accelerate the depletion of existing cash reserves.

Volatile Working Capital Management

According to recent SEC filings, working capital fluctuations have been significant, including a $12.3M cash drain in 2025Q4, which suggests that the timing of milestone-related receivables and payables creates substantial quarterly volatility in the company's underlying cash position.

These swings in working capital appear to be a direct consequence of the company's milestone-heavy revenue model. The erratic nature of these cash movements makes it difficult to forecast short-term liquidity needs, necessitating a cautious approach when evaluating the company's operational efficiency.

SBC Obscures True Operational Costs

As observed in the cash flow data, stock-based compensation consistently adds back millions to operating cash flow, with $3.0M recorded in 2025Q3, effectively masking the true economic cost of talent acquisition and retention during this critical pre-commercial development phase.

By adjusting for stock-based compensation, the underlying cash burn appears even more severe than the headline operating cash flow figures suggest. This practice may indicate that the company is utilizing equity to preserve cash, which, while prudent for liquidity, may lead to significant dilution for existing shareholders over the long term.

OBIO — Frequently Asked Questions

Quick answers to the most common questions about buying OBIO stock.

How much cash does Orchestra BioMed Holdings, Inc. (OBIO) generate from operations?

Orchestra BioMed Holdings, Inc. (OBIO) generated $-49.0M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.

What is Orchestra BioMed Holdings, Inc.'s free cash flow?

Orchestra BioMed Holdings, Inc. (OBIO) reported negative free cash flow of $49.5M in 2025, indicating capital requirements exceeded cash from operations.

What is Orchestra BioMed Holdings, Inc.'s capital expenditure (CapEx)?

Orchestra BioMed Holdings, Inc. (OBIO) spent $0.5M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.