Orchestra BioMed Holdings, Inc. (OBIO) Revenue History
Annual and quarterly revenue from 2020 to present
OBIO Revenue Over Time (2020–2025)
OBIO Revenue Growth History
2 of 5 years with positive growth- FY2020 revenue growth
- N/A
- FY2021 revenue growth
- -113.7%
- FY2022 revenue growth
- +551.8%
- FY2023 revenue growth
- -21.9%
- FY2024 revenue growth
- -4.4%
- FY2025 revenue growth
- +1169.2%
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $110K | -87.3% |
| Q4 2025 | $30.9M | +12120.2% |
| Q3 2025 | $861K | -12.8% |
| Q2 2025 | $836K | +7.5% |
| Q1 2025 | $868K | +40.0% |
| Q4 2024 | $253K | -3.4% |
| Q3 2024 | $987K | +135.6% |
| Q2 2024 | $778K | -15.0% |
Multi-year avg. share of annual revenue by fiscal quarter
Revenue Breakdown (FY 2025)
OBIO's revenue distribution by segment and geography for fiscal year 2025
By Product/Segment
OBIO Revenue Analysis (2020–2025)
Current Revenue & Growth
As of June 30, 2026, Orchestra BioMed Holdings, Inc. (OBIO) generated trailing twelve-month (TTM) revenue of $32.7 million, reflecting significant decline in growth of -87.3% year-over-year. The most recent quarter (Q1 2026) recorded $110,000 in revenue, down 99.6% sequentially.
Historical Growth Trajectory
OBIO's 5-year compound annual growth rate (CAGR) stands at +42.5%, indicating outstanding long-term growth trajectory. The 3-year CAGR of +111.6% exceeds the 5-year average, indicating an acceleration in the most recent period. Orchestra BioMed Holdings, Inc.'s highest annual revenue of $33.5 million was recorded in 2025, an all-time high.
Revenue by Segment
OBIO's revenue is primarily driven by Product (100%). With over half of revenue concentrated in Product, the company has a focused business model while developing other growth vectors.
Peer Comparison
Compared to Healthcare sector peers — including NVCR (+8.5% YoY), XTNT (-0.3% YoY), and BSX (+17.4% YoY) — OBIO has underperformed the peer group in revenue growth. Compare OBIO vs NVCR →
OBIO Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| OBIOCurrent | $33M | -87.3% | +42.5% | -154.7% | |
 NVCR | $655M | +8.5% | +5.8% | -23.5% | |
 XTNT | $134M | -0.3% | +20.2% | 5.4% | |
 BSX | $20.1B | +17.4% | +15.2% | 19.8% | |
 MDT | $36.4B | +8.4% | +3.8% | 17.8% | |
 ABT | $44.3B | +6.6% | +5.1% | 18.2% |
OBIO Historical Revenue Data (2020–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $33.5M | +1169.2% | $33.3M | 99.4% | $-51,807,000 | -154.7% |
| 2024 | $2.6M | -4.4% | $2.4M | 92.3% | $-64,301,000 | -2437.5% |
| 2023 | $2.8M | -21.9% | $2.6M | 93.3% | $-51,506,000 | -1866.2% |
| 2022 | $3.5M | +551.8% | $3.2M | 90.9% | $-32,657,000 | -924.3% |
| 2021 | $-782,000 | -113.7% | $-981,000 | 125.4% | $-21,799,000 | 2787.6% |
| 2020 | $5.7M | - | $5.6M | 97.5% | $-18,752,000 | -328.8% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
6+ years return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
OBIO — Frequently Asked Questions
Quick answers to the most common questions about buying OBIO stock.
Is OBIO's revenue growth accelerating or slowing?
OBIO revenue is declining -87.3% year-over-year. TTM revenue fell to $33M, contrasting with the 5-year CAGR of +42.5%. The reversal reflects either macro headwinds or company-specific challenges.
What is OBIO's revenue history from 2020 to 2026?
Orchestra BioMed Holdings, Inc. (OBIO) revenue history spans 2020 to 2026. TTM revenue as of 2026 is $33M, growing at -87.3% YoY. The 5-year CAGR is +42.5%. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is OBIO's long-term revenue growth rate (CAGR)?
Orchestra BioMed Holdings, Inc.'s 5-year revenue CAGR of +42.5% reflects the variable nature of its business expansion. As of 2026, the current YoY growth rate of -87.3% is below this long-term average. CAGR is the most reliable measure of sustained revenue momentum for OBIO.
Why does OBIO's quarterly revenue fluctuate?
OBIO quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. Orchestra BioMed Holdings, Inc.'s revenue data from 2020 to 2026 shows full historical quarterly detail on this page.
How is OBIO's revenue distributed by segment?
OBIO reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does OBIO's revenue compare to industry peers?
Orchestra BioMed Holdings, Inc. (OBIO) with TTM revenue of $33M and -87.3% YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.