Free cash flow burn accelerated from -$34.1M in 2024Q1 to -$70.6M in 2026Q2, with operating cash outflows averaging $55M per quarter and no capital returns, reflecting a pure reinvestment strategy.
Ocular Therapeutix, Inc. (OCUL) cash flow statement — 14-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 |
|---|
| Cash from Operations | -238.24M | -204.88M | -134.68M | -70.23M | -59.6M | -65.55M | -53.55M | -77.58M | -49.23M | -50.47M | -34M | -33.74M | -20.5M | -12.64M | -12.59M |
| Operating CF Margin % | - | -395.35% | -211.35% | -120.18% | -115.75% | -150.61% | -307.73% | -1835.3% | -2473.72% | -2624.7% | -1801.85% | -1928.17% | -2654.92% | - | -125850% |
| Operating CF Growth % | -145.85% | -52.13% | -91.75% | -17.84% | 9.07% | -22.4% | 30.97% | -57.59% | 2.47% | -48.45% | -0.76% | -64.63% | -62.09% | -0.48% | - |
| Net Income | -301.45M | -265.94M | -193.51M | -80.74M | -71.04M | -6.55M | -155.64M | -86.37M | -59.98M | -63.39M | -44.7M | -39.75M | -28.65M | -13.32M | -14.09M |
| Depreciation & Amortization | 5.45M | 4.32M | 3.79M | 2.98M | 2.11M | 2.42M | 2.77M | 2.53M | 2.29M | 1.63M | 881K | 754K | 547K | 404K | 404K |
| Stock-Based Compensation | 53.28M | 43.18M | 33.11M | 17.82M | 16.96M | 14.98M | 7.53M | 8.76M | 7.48M | 7.32M | 5.96M | 4.64M | 2.64M | 476K | 243K |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 86.19M | -4.3M | 0 | 9K | 1.42M | -58K | 332K | -14K | 49K |
| Other Non-Cash Items | 6.85M | 5.84M | 32.16M | -2.9M | -8.99M | -73.49M | 4.41M | 3.68M | 397K | 408K | 371K | 166K | 2.47M | 46K | 86K |
| Working Capital Changes | -2.37M | 7.71M | -10.23M | -7.41M | 1.35M | -2.9M | 1.18M | -1.88M | 585K | 3.55M | 2.08M | 503K | 2.16M | -240K | 726K |
| Change in Receivables | 151K | 1.74M | -6.21M | -4.85M | -190K | -8.88M | -9.7M | -2.35M | 25K | 24K | -57K | 136K | -60K | -224K | 77K |
| Change in Inventory | -787K | -524K | -735K | -331K | -724K | -49K | -247K | -737K | -95K | -9K | 21K | -1K | -133K | -92K | 496K |
| Change in Payables | 1.29M | -887K | -318K | 583K | -621K | 1.8M | -452K | 124K | -796K | 932K | -159K | 348K | 507K | -174K | 145K |
| Cash from Investing | -16.86M | -11.88M | -1.29M | -6.09M | -3.71M | -1.19M | -841K | -2.24M | -1.89M | 27.07M | 35.57M | -38.57M | -38.59M | -387K | 3.81M |
| Capital Expenditures | -16.86M | -12.01M | -1.29M | -6.09M | -3.71M | -1.19M | -841K | -2.24M | -1.89M | -8.25M | -1.92M | -1.78M | -1.26M | -387K | -203K |
| CapEx % of Revenue | 32.39% | 23.18% | 2.02% | 10.42% | 7.21% | 2.74% | 4.83% | 52.95% | 94.92% | 429.12% | 101.7% | 101.6% | 163.21% | - | 2030% |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5K | 2K | 7K | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 130K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 114K | -1.5M | 60K | -37.33M | 0 | 4.02M |
| Cash from Financing | 462.61M | 561.72M | 332.11M | 169.83M | 1.45M | 2.85M | 228.01M | 75.34M | 68.64M | 32.01M | 585K | 65.7M | 78.97M | 6.68M | 27.3M |
| Debt Issued (Net) | 0 | 0 | 316.35M | 56.35M | 0 | -445K | 0 | 37.27M | 6.38M | 2.4M | 0 | 397K | 12.6M | -1.82M | 3.51M |
| Equity Issued (Net) | 462.61M | 561.72M | 316.35M | 118.11M | 940K | 985K | 224.68M | 37.54M | 61.57M | 29.24M | 627K | 65.61M | 69.52M | 8.49M | 23.78M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | 0 | -300.6M | -4.63M | 514K | 2.31M | 3.33M | 529K | 694K | 370K | -42K | -306K | -3.15M | 7K | 3K |
| Net Change in Cash | 207.51M | 344.96M | 196.15M | 93.51M | -61.86M | -63.89M | 173.62M | -4.47M | 17.52M | 8.6M | 2.15M | -6.61M | 19.89M | -6.35M | 18.52M |
| Free Cash Flow | -255.1M | -216.89M | -135.97M | -76.32M | -63.32M | -66.74M | -54.4M | -79.82M | -51.12M | -58.73M | -35.92M | -35.52M | -21.76M | -13.03M | -12.79M |
| FCF Margin % | -490.07% | -418.53% | -213.37% | -130.59% | -122.96% | -153.36% | -312.56% | -1888.24% | -2568.64% | -3053.82% | -1903.55% | -2029.77% | -2818.13% | - | -127880% |
| FCF Growth % | -42.22% | -59.52% | -78.15% | -20.54% | 5.13% | -22.7% | 31.85% | -56.15% | 12.96% | -63.49% | -1.12% | -63.27% | -66.94% | -1.91% | - |
| FCF per Share | -1.13 | -1.16 | -0.86 | -0.89 | -0.77 | -0.81 | -0.90 | -1.76 | -1.34 | -2.04 | -1.45 | -1.53 | -2.04 | -4.41 | -4.33 |
| FCF Conversion (FCF/Net Income) | 0.85x | 0.77x | 0.70x | 0.87x | 0.84x | 10.00x | 0.34x | 0.90x | 0.85x | 0.80x | 0.76x | 0.85x | 0.72x | 0.95x | 0.89x |
| Interest Paid | 6.77M | 9.03M | 21.53M | 5.46M | 2.15M | 1.93M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying OCUL stock.
Ocular Therapeutix, Inc. (OCUL) generated $-204.9M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Ocular Therapeutix, Inc. (OCUL) reported negative free cash flow of $216.9M in 2025, indicating capital requirements exceeded cash from operations.
Ocular Therapeutix, Inc. (OCUL) spent $12.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Single-asset clinical dependency
Metrics are mathematically derived from official filings.
Cash Conversion Lags Reported Losses
Operating cash outflows averaged $55M per quarter over the last five quarters, consistently exceeding net losses, with OCF/NI ratios between 0.70 and 0.85, indicating accrual-based losses understate cash burn.
The gap between net income and operating cash flow is modest but persistent, with OCF/NI ratios below 1.0 in most quarters, suggesting that non-cash charges like SBC and D&A are partially offset by working capital outflows. The negative working capital changes in several quarters, such as -$5.0M in 2026Q2, imply that cash is being consumed by operational needs beyond the reported loss. This pattern is typical for a clinical-stage biotech scaling R&D, but the consistency of the gap warrants monitoring for any deterioration in cash conversion efficiency.
FCF Burn Accelerates with R&D Scaling
Free cash flow deteriorated from -$34.1M in 2024Q1 to -$70.6M in 2026Q2, with FCF margins worsening from -2.3% to -5.2%, reflecting a doubling of cash burn as AXPAXLI trials intensify.
The FCF trajectory shows a clear inflection point around 2024Q1, coinciding with the strategic pivot to retina, and has since steepened. Quarterly FCF burn has roughly doubled from the mid-$30M range to over $70M, driven primarily by operating losses rather than capex, which remains modest. This suggests the company is in a deliberate investment phase, but the accelerating burn rate implies a finite runway that investors should track against the $737M cash balance.
Capex Minimal, R&D Drives Burn
Capital expenditures remain negligible, averaging under $3M per quarter, with CapEx/Revenue spiking to 25% in 2026Q2 only due to low revenue, indicating the business is asset-light and cash burn is R&D-driven.
Capex is not a meaningful cash outflow for OCUL, as the company appears to rely on contract manufacturing and existing facilities. The high CapEx/Revenue ratios in recent quarters are an artifact of declining revenue rather than increased investment. This implies that the company's cash burn is almost entirely operational, tied to clinical trial costs and headcount, and that future capital needs will likely be for commercial manufacturing scale-up if AXPAXLI is approved.
Working Capital Swings Reflect Trial Timing
Working capital changes have been volatile, ranging from -$13.0M in 2024Q1 to +$5.5M in 2025Q1, with no clear trend, suggesting timing of vendor payments and trial-related receivables rather than inventory issues.
The working capital line items show no consistent pattern, with both positive and negative swings across quarters. This volatility likely stems from the lumpy nature of clinical trial expenses and milestone payments, as well as the timing of collections from the Regeneron collaboration. The absence of a persistent working capital drag suggests that the company is managing its payables and receivables adequately, but the swings add noise to quarterly cash flow comparisons.
No Capital Returns, All Cash to Pipeline
OCUL has paid no dividends and repurchased no shares over the past ten quarters, with all cash directed to R&D and operations, reflecting a pure reinvestment strategy focused on AXPAXLI development.
The capital deployment is singularly focused on advancing the pipeline, with zero cash returned to shareholders. This is consistent with a clinical-stage biotech that needs to preserve cash for trials and potential regulatory milestones. The absence of buybacks or dividends is not a concern at this stage, but it underscores that the company's value creation is entirely dependent on successful clinical outcomes, particularly for AXPAXLI.
Cumulative Losses Outpace Cash Burn
Over the ten quarters, cumulative net losses of $626.7M exceed cumulative operating cash outflows of $472.8M, indicating that non-cash charges like SBC and D&A are inflating reported losses relative to actual cash consumption.
The cumulative gap between net income and operating cash flow is approximately $154M, driven by significant stock-based compensation and depreciation. This suggests that the company's cash runway is longer than the reported losses imply, but the gap also highlights the dilutive impact of SBC on shareholders. Investors should note that while cash burn is high, it is somewhat lower than the accounting losses, providing a slight cushion to the $737M cash balance.
What Could Invalidate the Base Case
The cash flow statement obscures the dilutive impact of stock-based compensation, which totaled $106.6M over ten quarters, and the potential for working capital swings to mask true operational burn, as seen in 2024Q1's -$13.0M change.
While the reported operating cash flow appears to understate the accounting losses, the significant SBC component suggests that the company's cash position is being supplemented by equity issuance, which dilutes existing shareholders. Additionally, the volatility in working capital changes, such as the -$13.0M in 2024Q1, could indicate timing differences in trial-related payables that may reverse in future periods, potentially accelerating cash burn. Investors should monitor the sustainability of the cash runway, especially if AXPAXLI trials face delays or if revenue from DEXTENZA continues to decline.