Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in OSTX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | VANGUARD CAPITAL MANAGEMENT LLC | 469K | $662K | β | 1.054% | 0.00% |
| 2 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 449K | $633K | β | 1.008% | 0.00% |
| 3 | CM Management, LLC | 400K | $564K | 0.0% | 0.898% | 0.47% |
| 4 | UBS Group AG | 349K | $492K | +1820.5% | 0.783% | 0.00% |
| 5 | GEODE CAPITAL MANAGEMENT, LLC | 280K | $395K | +13.8% | 0.629% | 0.00% |
| 6 | HOWARD FINANCIAL SERVICES, LTD. | 245K | $346K | β | 0.551% | 0.04% |
| 7 | VANGUARD FIDUCIARY TRUST CO | 117K | $164K | β | 0.262% | 0.00% |
| 8 | STATE STREET CORP | 91K | $129K | +55.9% | 0.205% | 0.00% |
| 9 | NORTHERN TRUST CORP | 66K | $93K | -7.4% | 0.148% | 0.00% |
| 10 | BlackRock, Inc. | 65K | $91K | +5.5% | 0.145% | 0.00% |
| 11 | Beacon Pointe Advisors, LLC | 63K | $88K | β | 0.140% | 0.00% |
| 12 | JANE STREET GROUP, LLC | 40K | $57K | +45.3% | 0.090% | 0.00% |
| 13 | SANDERS MORRIS HARRIS LLC | 32K | $45K | β | 0.072% | 0.01% |
| 14 | XTX Topco Ltd | 32K | $45K | β | 0.071% | 0.00% |
| 15 | TWO SIGMA INVESTMENTS, LP | 26K | $37K | -69.9% | 0.059% | 0.00% |
| 16 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 25K | $35K | 0.0% | 0.056% | 0.00% |
| 17 | Vanguard Global Advisers, LLC | 21K | $30K | β | 0.047% | 0.00% |
| 18 | HighTower Advisors, LLC | 15K | $21K | β | 0.034% | 0.00% |
| 19 | STIFEL FINANCIAL CORP | 15K | $21K | 0.0% | 0.034% | 0.00% |
| 20 | Stratos Wealth Advisors, LLC | 14K | $19K | 0.0% | 0.031% | 0.00% |
| 21 | JONES FINANCIAL COMPANIES LLLP | 13K | $18K | +18.9% | 0.029% | 0.00% |
| 22 | MERCER GLOBAL ADVISORS INC /ADV | 10K | $14K | 0.0% | 0.023% | 0.00% |
| 23 | LPL Financial LLC | 10K | $14K | 0.0% | 0.023% | 0.00% |
| 24 | MORGAN STANLEY | 9K | $13K | +849.0% | 0.021% | 0.00% |
| 25 | Tower Research Capital LLC (TRC) | 4K | $6K | +4648.9% | 0.009% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in OSTX β a direct measure of their conviction.
Filings activity in OSTX during Q1 2026, grouped by how each filer changed its position.
7 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 29 | +21% | 5.33% | +2.11 pp | $4M | +66% |
| Q4 2025 | 24 | 4.0% | 3.22% | 0.54 pp | $2M | 14% |
| Q3 2025 | 25 | +79% | 3.76% | +2.41 pp | $3M | +177% |
| Q2 2025 | 14 | +100% | 1.35% | +0.63 pp | $1M | +89% |
| Q1 2025 | 7 | +17% | 0.72% | 0.10 pp | $1M | 12% |
| Q4 2024 | 6 | 25% | 0.82% | +0.33 pp | $1M | +67% |
| Q3 2024 | 8 | β | 0.49% | β | $0M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying OSTX stock.
Based on Q1 2026 13F filings, institutional ownership of OS Therapies Incorporated stands at 5.3%, held across 29 reporting institutions.
VANGUARD CAPITAL MANAGEMENT LLC is the largest reported institutional holder of OSTX, with approximately 469,467 shares worth $0.00B as of Q1 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of OSTX, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, JANE STREET GROUP, LLC, TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for OSTX is 75 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
11 institutions opened new positions in OSTX during Q1 2026, while 6 fully exited. 16 added to existing positions and 2 trimmed.
OSTX institutional ownership rose by 2.11 percentage points quarter-over-quarter, with a net change of +5 holders.
The top 10 institutions account for 88.5% of all reported 13F value in OSTX, and the top 25 account for 100.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
OS Therapies Incorporated (OSTX) Institutional Ownership