Bull case
The bull case prices PEN at 36x on FY1 earnings, assuming continued execution and no meaningful deceleration in the core business.
Wall Street verdict, consensus price target, and analyst rating breakdown — everything needed to frame the risk/reward at today's price.
Three scenarios for where PEN stock could go
The bull case prices PEN at 36x on FY1 earnings, assuming continued execution and no meaningful deceleration in the core business.
At 27x on FY1 earnings, the base case reflects a reasonable but not stretched valuation. It prices in continued growth without assuming an exceptional setup.
If investor confidence fades or macro conditions deteriorate, a 47x multiple contraction could push PEN down roughly 73% from where it trades now.
Not financial advice. Model confidence reflects internal scenario assumptions, not a guarantee of returns. Past performance does not predict future results.

Penumbra is a medical device company specializing in minimally invasive neurovascular and peripheral vascular therapies. It generates revenue primarily from sales of its proprietary thrombectomy systems—which remove blood clots—and embolization devices, with neurovascular products representing the largest segment. The company's competitive advantage lies in its innovative aspiration-based technology platform that offers differentiated clinical outcomes in stroke treatment and other vascular conditions.
Quarterly beat-or-miss track record against analyst estimates, plus forward revenue and EPS outlook for the next two fiscal years.
| Quarter | EPS (Actual / Est) | EPS Surprise | Revenue (Actual / Est) | Rev Surprise |
|---|---|---|---|---|
| Q3 2025 | $0.86/$0.81 | +6.2% | $339M/$341M | -0.6% |
| Q4 2025 | $0.97/$0.93 | +4.4% | $355M/$341M | +4.0% |
| Q1 2026 | $1.18/$1.11 | +6.3% | $385M/$362M | +6.5% |
| Q2 2026 | $0.82/$1.04 | -21.2% | $375M/$370M | +1.2% |
PEN beat EPS estimates in 3 of 4 tracked quarters. A strong delivery record supports forward estimate credibility.
Product and geographic revenue mix from the latest annual disclosure, with year-over-year growth by segment.
Latest annual revenue by segment or product family
Latest annual revenue by reported region
Tap, hover, or focus a slice to inspect segment detail.
Current multiples compared to the S&P 500, the company's sector, and its own five-year average.
Fair value est. $109 — implies -65.5% from today's price.
| Metric | PEN | S&P 500 | Healthcare | 5Y Avg PEN |
|---|---|---|---|---|
| Forward PE | 64.4x | 18.8x+242% | 18.3x+252% | — |
| Trailing PE | 70.2x | 24.4x+187% | 22.1x+217% | 88.6x-21% |
| PEG Ratio | — | 1.66x | 1.59x | — |
| EV/EBITDA | 60.5x | 15.2x+298% | 14.2x+326% | 78.9x-23% |
| Price/FCF | 71.3x | 20.7x+245% | 18.5x+285% | 84.4x-16% |
| Price/Sales | 8.9x | 3.1x+187% | 2.6x+237% | 10.1x-12% |
| Dividend Yield | — | 1.91% | 1.50% | — |
Forward P/E and PEG reflect analyst consensus estimates. Historical averages use trailing ratios where forward data is unavailable.S&P 500 and sector benchmarks both use trailing median P/E — similar readings indicate the broader index and sector are priced alike.
Open valuation toolPEN generates $213M in free cash flow at a 14.6% margin — 11.3% ROIC signals a durable competitive advantage.
Revenue, margins, and cash generation
ROIC, leverage, and debt serviceability
~0.2 years to full repayment at current FCF run-rate
How capital is returned to owners
All figures from the trailing twelve months. ROIC uses invested capital (equity + net debt).
Open full ratios pageKey factors that could pressure the stock price, compress the multiple, or weigh on future results.
AI analysis · updated June 18, 2026
The stock has a modest implied upside of +12.8% to +13.0% based on consensus targets, suggesting limited near-term upside potential.
Penumbra faces strong competition from established players like Stryker and Medtronic in the interventional medical device space.
The stock has shown minimal daily gains (0.08%) and trades within a narrow range, indicating weak momentum.
Future growth projections are mixed, with detailed analysis required to assess long-term performance against industry benchmarks.
These are risk mechanisms, not predictions. The key question is which would force a cut to earnings estimates or a lower multiple than the market currently prices in.
Structural drivers behind the upside case and why the stock could outperform over the next 12 months.
AI analysis · updated June 18, 2026
Penumbra has a competitive advantage in thrombectomy technology, which is a key driver of its growth and market position.
The company is capitalizing on growing international demand for its medical devices, further boosting its revenue potential.
Penumbra's stock has risen significantly, reflecting the successful execution of its growth strategy and bullish thesis.
A real bull case compounds — each driver matters most when it strengthens margins, supports capital returns, and keeps the company above the market's minimum growth bar simultaneously.
52-week range context and price returns across multiple time horizons. Dividend contribution is shown separately in the Capital Return section.
Range context matters because valuation compression and earnings misses rarely hit from the same starting point. A stock already far below its high can still fall, but it is no longer carrying the same embedded optimism as one pressing a fresh peak.
Valuation, growth, and margin comparison against the closest publicly traded peers for this company.
| Company | Mkt Cap | Fwd PE | Rev Grw | Margin | Rating | Upside |
|---|---|---|---|---|---|---|
PEN PEN Penumbra, Inc. | $12.5B | 64.4x | +11.5% | 11.8% | Hold | +16.1% |
ISR ISRG Intuitive Surgical, Inc. | $144.5B | 38.9x | +10.2% | 28.2% | Buy | +47.0% |
NVC NVCR NovoCure Limited | $1.6B | — | +9.0% | -25.7% | Buy | +131.1% |
NVS NVST Envista Holdings Corp | $4.2B | 18.1x | +3.1% | 2.4% | Hold | +9.3% |
INV INVA Innoviva, Inc. | $1.7B | 6.3x | +20.6% | 118.9% | Buy | +64.5% |
SYK SYK Stryker Corporation | $117.9B | 20.5x | +10.1% | 12.9% | Buy | +25.9% |
This peer comparison reflects companies with similar business models, product lines, or market positioning, supplemented by industry grouping when direct matches are limited.
Common questions answered from live analyst data and company financials.
Penumbra, Inc. (PEN) is rated Hold by Wall Street analysts as of 2026. Of 22 analysts covering the stock, 9 rate it Buy or Strong Buy, 13 rate it Hold, and 0 rate it Sell or Strong Sell. The consensus 12-month price target is $368, implying +16.1% from the current price of $317. The bear case scenario is $85 and the bull case is $178.
The Wall Street consensus price target for PEN is $368 based on 22 analyst estimates. The high-end target is $374 (+17.9% from today), and the low-end target is $335 (+5.6%). The base case model target is $135.
PEN trades at 64.4x times forward earnings. The stock trades at a notable premium to the broad market, which is typical for businesses with strong free cash flow and above-average growth expectations. Based on current multiples versus the peer group, the relative model signals expensive versus peers. Whether the stock is over or undervalued ultimately depends on whether consensus earnings estimates are achievable.
The primary risks for PEN in 2026 are: (1) Competitive pressure — Penumbra faces strong competition from established players like Stryker and Medtronic in the interventional medical device space. (2) Valuation risk — The stock has a modest implied upside of +12. (3) Market performance — The stock has shown minimal daily gains (0. Each factor has the potential to pressure earnings or compress the stock's valuation multiple.
Analyst consensus estimates PEN will report consensus revenue of $1.6B (+11.5% year-over-year) and EPS of $3.38 (-21.8% year-over-year) for the upcoming fiscal year. The following year, analysts project $1.8B in revenue.
Penumbra, Inc. is expected to report its next earnings on approximately 2026-08-04. Consensus expects EPS of $1.18 and revenue of $389M. Over recent quarters, PEN has beaten EPS estimates 83% of the time.
Penumbra, Inc. (PEN) generated $213M in free cash flow over the trailing twelve months — a free cash flow margin of 14.6%. PEN returns capital to shareholders through and share repurchases ($0 TTM).