90% buyers of institutions opening or closing positions this quarter
16 more new buyers than exits, ownership rose 109.08 percentage points vs the prior quarter, and no widely-followed fund managers in the top 25.
90% buyers of institutions opening or closing positions this quarter
111.7% institutional ownership
Yu Fan portfolio allocation
Institutional ownership vs Biotechnology peers
1 Form 4 filings β executives buying or selling their own stock
Latest positioning in PMN across 13F flow, ownership shift, marquee holders, and holder-count growth.
Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in PMN held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | JANUS HENDERSON GROUP PLC | 1.3M | $16.4M | β | 19.804% | 0.01% |
| 2 | Deep Track Capital, LP | 836K | $10.6M | β | 12.801% | 0.17% |
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 696K | $8.8M | β | 10.668% | 0.00% |
| 4 | Trails Edge Capital Partners, LP | 557K | $7.1M | β | 8.534% | 1.62% |
| 5 | Ally Bridge Group (NY) LLC | 414K | $5.3M | +66.1% | 6.345% | 4.25% |
| 6 | Woodline Partners LP | 395K | $5.0M | β | 6.056% | 0.02% |
| 7 | GREAT POINT PARTNERS LLC | 371K | $4.7M | β | 5.690% | 1.08% |
| 8 | Yu Fan | 330K | $4.2M | β | 5.052% | 4.32% |
| 9 | SPHERA FUNDS MANAGEMENT LTD. | 326K | $4.1M | +2657.6% | 4.988% | 0.66% |
| 10 | Squadron Capital Management LLC | 325K | $4.1M | β | 4.978% | 1.51% |
| 11 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 139K | $1.8M | β | 2.134% | 0.00% |
| 12 | ADAR1 Capital Management, LLC | 95K | $1.2M | β | 1.461% | 0.07% |
| 13 | 683 Capital Management, LLC | 93K | $1.2M | β | 1.422% | 0.06% |
| 14 | MILLENNIUM MANAGEMENT LLC | 78K | $990K | β | 1.194% | 0.00% |
| 15 | Empery Asset Management, LP | 60K | $766K | β | 0.925% | 0.92% |
| 16 | Ikarian Capital, LLC | 55K | $699K | β | 0.843% | 0.06% |
| 17 | HEIGHTS CAPITAL MANAGEMENT, INC | 51K | $643K | β | 0.776% | 0.18% |
| 18 | BOOTHBAY FUND MANAGEMENT, LLC | 16K | $204K | β | 0.246% | 0.00% |
| 19 | Seven Fleet Capital Management LP | 11K | $135K | β | 0.162% | 0.04% |
| 20 | UBS Group AG | 1K | $17K | -10.3% | 0.020% | 0.00% |
| 21 | ADVISOR GROUP HOLDINGS, INC. | 360 | $5K | 0.0% | 0.006% | 0.00% |
| 22 | ROYAL BANK OF CANADA | 268 | $4K | +22.9% | 0.004% | 0.00% |
| 23 | Steward Partners Investment Advisory, LLC | 100 | $1K | β | 0.002% | 0.00% |
| 24 | Federation des caisses Desjardins du Quebec | 10 | $127 | -97.0% | 0.000% | 0.00% |
| 25 | TD Waterhouse Canada Inc. | 5 | $65 | -80.0% | 0.000% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in PMN β a direct measure of their conviction.
Filings activity in PMN during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new PMN position in Q1 2026
Institutions that fully closed their PMN position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 25 | +178% | 111.70% | +109.08 pp | $78M | +4238% |
| Q4 2025 | 9 | 61% | 2.62% | 3.52 pp | $2M | 57% |
| Q3 2025 | 23 | +15% | 6.14% | +0.17 pp | $4M | +2.9% |
| Q2 2025 | 20 | +11% | 5.97% | 3.31 pp | $4M | 37% |
| Q1 2025 | 18 | 5.3% | 9.28% | 4.18 pp | $6M | 30% |
| Q4 2024 | 19 | 5.0% | 13.46% | 4.97 pp | $9M | 27% |
| Q3 2024 | 20 | +18% | 18.43% | +11.30 pp | $13M | +159% |
| Q2 2024 | 17 | β | 7.13% | β | $5M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Latest Form 4 transactions by company officers and directors. Insider buys are widely viewed as the highest-conviction signal because executives are risking personal capital.
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| Apr 22, 2026 | Kirwin Patrick D. | Buy | 4K | $11.33 | $45K |
Quick answers to the most common questions about buying PMN stock.
Based on Q1 2026 13F filings, institutional ownership of ProMIS Neurosciences, Inc. stands at 111.7%, held across 25 reporting institutions.
JANUS HENDERSON GROUP PLC is the largest reported institutional holder of PMN, with approximately 1,292,757 shares worth $0.02B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of PMN.
Our composite Smart Money Score for PMN is 59 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
18 institutions opened new positions in PMN during Q1 2026, while 2 fully exited. 5 added to existing positions and 2 trimmed.
PMN institutional ownership rose by 109.08 percentage points quarter-over-quarter, with a net change of +16 holders.
The top 10 institutions account for 90.2% of all reported 13F value in PMN, and the top 25 account for 100.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.