Free cash flow remains deeply negative at -$45.5 million for 2026Q1, reflecting a persistent burn rate that significantly outpaces accounting losses.
| Cash from Operations | -132.21M | -120.12M | -126.35M | -90.07M | -77.09M | -50.3M | -25.18M | -76.81K |
| Operating CF Margin % | - | -13450.95% | -166251.32% | - | - | - | - | - |
| Operating CF Growth % | -48.37% | 4.93% | -40.28% | -16.84% | -53.26% | -99.75% | -32685.2% | - |
| Net Income | -74.84M | -151.61M | -163.34M | -135.45M | -148.13M | -55.15M | -26.75M | -79.61K |
| Depreciation & Amortization | 6.63M | 6.58M | 5.43M | 3.85M | 3.04M | 1.98M | 964K | 867 |
| Stock-Based Compensation | 17.19M | 25.34M | 29.37M | 30.85M | 74.47M | 699K | 730K | 498 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -13.87M | -1.7M | -1.78M | -6M | 0 | 0 | 0 | 1.56K |
| Working Capital Changes | -5.26M | 1.28M | 3.96M | 16.67M | -6.46M | 2.16M | -126K | -115 |
| Change in Receivables | 182K | 1.32M | -1.07M | -1.38M | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | -6.03M | -5.92M | 11.59M | 11.64M | 494K | 5K | 683K | 0 |
| Cash from Investing | 110.5M | 103.97M | 20.41M | -329.98M | -1.74M | -5.19M | -5.46M | -2.97K |
| Capital Expenditures | -17.85M | -15.2M | -29.51M | -34.2M | -1.85M | -5.19M | -5.46M | -1.3K |
| CapEx % of Revenue | 2007.42% | 1701.68% | 38827.63% | - | - | - | - | - |
| Acquisitions | 18.21M | 18.21M | 0 | 0 | 108K | 1K | 0 | -1.66K |
| Investments | - | - | - | - | - | - | - | - |
| Other Investing | 34.22M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Financing | 25.8M | 25.57M | 144.41M | -9.55M | 548.52M | 71.47M | 19.99M | 20K |
| Debt Issued (Net) | -17K | -26K | -54K | -52K | -32K | -30K | -11K | 0 |
| Equity Issued (Net) | 17.86M | 25.59M | 144.32M | -9.5M | 6.05M | 71.5M | 0 | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | -9.5M | 0 | 0 | 0 | 0 |
| Other Financing | 7.96M | 0 | 140K | 0 | 542.5M | 0 | 20M | 20K |
| Net Change in Cash | 4.09M | 9.42M | 38.47M | -429.6M | 469.69M | 15.98M | -10.65M | 15.23K |
| Free Cash Flow | -150.06M | -135.31M | -155.86M | -124.27M | -78.94M | -55.49M | -30.64M | -78.11K |
| FCF Margin % | -16879.08% | -15152.63% | -205078.95% | - | - | - | - | - |
| FCF Growth % | 0.61% | 13.18% | -25.42% | -57.43% | -42.25% | -81.12% | -39122.39% | - |
| FCF per Share | -1.06 | -1.01 | -1.59 | -2.01 | -1.28 | -1.74 | -0.16 | -0.00 |
| FCF Conversion (FCF/Net Income) | 2.01x | 1.74x | 2.07x | 2.54x | 0.71x | 0.91x | 0.94x | 0.00x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 73K | 2.86M | 1.95M | 68K | 145K | 0 |
Clinical Trial Execution Risk
As reported in recent financial statements, ProKidney consistently exhibits an OCF/NI ratio significantly above 1.0, with 2026Q1 figures showing a 1.85 multiple, indicating that cash outflows are substantially outpacing accounting losses as the company funds its intensive clinical development phase through rapid cash consumption.
The consistent gap between net income and operating cash flow suggests that the company's accounting losses do not fully capture the intensity of its cash burn. Investors should monitor this divergence, as it implies that the underlying operational requirements for the REACT platform are more capital-intensive than the income statement alone would suggest.
Based on quarterly data, ProKidney's free cash flow trajectory remains firmly in negative territory, with 2026Q1 outflows reaching $45.5 million, reflecting the heavy financial burden of sustaining concurrent Phase III clinical trials without any meaningful offsetting revenue streams to stabilize the company's cash position.
The persistent negative FCF margin, which hit -201.2% in the most recent quarter, underscores the binary nature of the company's current financial profile. This trajectory appears unsustainable without continued external financing, as the company lacks the operational scale to generate internal cash to fund its research pipeline.
According to recent SEC filings, ProKidney's capital expenditure has fluctuated significantly, peaking at 25.6% of revenue in 2025Q4, which highlights the substantial investment required to build out the specialized manufacturing infrastructure necessary for its autologous cell therapy platform as it approaches potential commercialization milestones.
The variability in capital spending suggests that the company is actively scaling its manufacturing capabilities, which is a critical but unproven component of its business model. Analysts should investigate whether these expenditures are sufficient to achieve the throughput required for commercial success or if further capital-intensive upgrades are pending.
As indicated by the provided financial data, ProKidney's capital deployment is almost exclusively directed toward funding clinical operations, with no dividends or share repurchases, and a notable $18.2 million acquisition outlay in 2025Q4 that warrants further investigation regarding its impact on the company's limited cash runway.
Management's decision to prioritize clinical trial funding over all other capital uses reflects a high-conviction strategy that leaves little room for error. The absence of shareholder returns is expected for a pre-revenue biotech, but the recent acquisition activity suggests a potential shift toward inorganic growth that could further strain liquidity.
Quick answers to the most common questions about buying PROK stock.
ProKidney Corp. (PROK) generated $-120.1M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
ProKidney Corp. (PROK) reported negative free cash flow of $135.3M in 2025, indicating capital requirements exceeded cash from operations.
ProKidney Corp. (PROK) spent $15.2M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.