Protagonist Therapeutics, Inc. (PTGX) Earnings History
Profitable12 years of earnings data (2014–2025) · Positive TTM net income
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Protagonist Therapeutics, Inc. (PTGX) Earnings Overview
As of October 3, 2026, Protagonist Therapeutics, Inc. (PTGX) reported trailing twelve-month net income of $83M, reflecting -148.5% year-over-year growth. The company earned $1.17 per diluted share over the past four quarters, with a net profit margin of -282.8%.
Looking at the long-term picture, PTGX's historical earnings data spans multiple years. The company achieved its highest annual net income of $275M in fiscal 2024.
Protagonist Therapeutics, Inc. maintains positive profitability with a gross margin of 97.3%, operating margin of -343.6%, and net margin of -282.8%. The company continues to generate positive earnings from operations. View revenue history →
Compared to peers including IMVT (-$538M net income), KYMR (-$300M net income, -794.4% margin), PRTA (-$44M net income, -2520.6% margin), PTGX has comparable earnings metrics. Compare PTGX vs IMVT →
PTGX Earnings vs Peers
Earnings metrics vs comparable public companies
PTGX Historical Earnings Data (2014–2025)
12 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | -$130M | -147.3% | -$158M | $-2.05 | -282.8% | -343.6% |
| 2024 | $275M | +448.5% | $253M | $4.23 | 63.3% | 58.2% |
| 2023 | -$79M | +38.0% | -$94M | $-1.39 | -131.6% | -156.1% |
| 2022 | -$127M | -1.5% | -$131M | $-2.52 | -479.3% | -494.2% |
| 2021 | -$126M | -89.8% | -$126M | $-2.65 | -458.9% | -460.0% |
| 2020 | -$66M | +14.3% | -$65M | $-1.92 | -231.1% | -225.4% |
| 2019 | -$77M | -98.3% | -$81M | $-2.98 | -33414.3% | -34857.6% |
| 2018 | -$39M | -5.3% | -$42M | $-1.74 | -125.9% | -136.7% |
| 2017 | -$37M | +0.6% | -$38M | $-2.09 | -184.2% | -188.9% |
| 2016 | -$37M | -150.2% | -$33M | $-5.72 | - | - |
| 2015 | -$15M | -34.2% | -$15M | $-2.52 | - | - |
| 2014 | -$11M | - | -$9M | $-1.88 | - | - |
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PTGX — Frequently Asked Questions
Quick answers to the most common questions about buying PTGX stock.
What is PTGX earnings per share (EPS)?
PTGX trailing twelve-month (TTM) diluted EPS is $1.17, reflecting -148.5% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2014 to 2025 is available in the table on this page.
What is Protagonist Therapeutics, Inc.'s net income?
Protagonist Therapeutics, Inc. (PTGX) trailing twelve-month net income is $83M as of 2025. Earnings declined -148.5% year-over-year.
Is PTGX profitable?
Yes, PTGX is profitable with a TTM net income of $83M and a net profit margin of -282.8%.
What is PTGX's earnings growth rate?
PTGX compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2014 to 2025.
What are PTGX's profit margins?
Protagonist Therapeutics, Inc. net profit margin is -282.8%, operating margin is -343.6%, and gross margin is +97.3%. Below-average margins reflect competitive or cost pressures. Return on Equity is -20.2%.
Is PTGX growing earnings?
PTGX earnings are declining — EPS fell -148.5% year-over-year. TTM net income dropped to $83M. This contrasts with the 5-year CAGR of N/A.
What was PTGX's best earnings year?
Protagonist Therapeutics, Inc.'s highest annual net income on record is $275M, achieved in fiscal year 2024. Earnings history on this page spans 2014 to 2025 and includes all annual and quarterly figures.
What were PTGX's earnings last quarter?
PTGX's most recent reported quarter was Q2 2026. Net income was $163M with diluted EPS of $2.29. For a full breakdown of all quarters, see the quarterly earnings table on this page.