Pyxis Oncology, Inc. (PYXS) Stock Price History
Historical prices from 2021 to 2026
- 1M
- -42.9%
- 3M
- -18.6%
- YTD
- +86.1%
- 1Y
- -4.9%
- 3Y
- +1.4%
- 5Y
- -30.5%
Loading 10-year price history...
PYXS Historical Performance
PYXS Annual Returns
Year-by-year price performance · 2021–2026
- 2021 annual price return
- -16.9%
- 2022 annual price return
- -88.3%
- 2023 annual price return
- +30.4%
- 2024 annual price return
- -24.3%
- 2025 annual price return
- -32.0%
- 2026 annual price return
- +130.4%
PYXS Stock Price Trajectory (2021–2026)
As of October 3, 2026, Pyxis Oncology, Inc. (PYXS) trades at $2.14, representing a -4.9% return over the past year. The stock has delivered a -83.8% total return over five years (-30.5% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $19.00 on October 8, 2021. From this peak, PYXS has corrected -88.7%, currently trading 0% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers IMVT (+101.0% 1Y), RCUS (+82.8% 1Y), and TPST (-92.5% 1Y), PYXS has underperformed the peer group average. Compare PYXS vs IMVT →
PYXS Historical Price Data · from 2021
Rows 1–50 of 1,251| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-10-02 | 2.21 | 2.31 | 2.10 | 2.14 | 1.99M | -2.28% |
| 2026-10-01 | 2.31 | 2.31 | 2.19 | 2.19 | 2.54M | -6.01% |
| 2026-09-30 | 2.38 | 2.39 | 2.12 | 2.33 | 8.13M | -19.66% |
| 2026-09-29 | 2.94 | 2.94 | 2.83 | 2.90 | 204K | 0.00% |
| 2026-09-28 | 2.81 | 2.90 | 2.75 | 2.90 | 351K | +1.40% |
| 2026-09-25 | 2.90 | 2.92 | 2.79 | 2.86 | 608K | -2.05% |
| 2026-09-24 | 3.22 | 3.22 | 2.86 | 2.92 | 872K | -9.32% |
| 2026-09-23 | 3.36 | 3.36 | 3.20 | 3.22 | 434K | -4.02% |
| 2026-09-22 | 3.21 | 3.40 | 3.21 | 3.35 | 479K | +5.17% |
| 2026-09-21 | 3.23 | 3.29 | 3.19 | 3.19 | 632K | -4.20% |
| 2026-09-18 | 3.42 | 3.44 | 3.33 | 3.33 | 563K | -2.35% |
| 2026-09-17 | 3.40 | 3.46 | 3.35 | 3.41 | 474K | +2.10% |
| 2026-09-16 | 3.34 | 3.40 | 3.32 | 3.34 | 639K | +0.30% |
| 2026-09-15 | 3.40 | 3.40 | 3.24 | 3.33 | 489K | -2.92% |
| 2026-09-14 | 3.21 | 3.52 | 3.21 | 3.43 | 699K | +6.85% |
| 2026-09-11 | 3.31 | 3.32 | 3.07 | 3.21 | 1.13M | -1.83% |
| 2026-09-10 | 3.42 | 3.44 | 3.19 | 3.27 | 738K | -3.25% |
| 2026-09-09 | 3.31 | 4.11 | 3.13 | 3.38 | 4.34M | -13.11% |
| 2026-09-08 | 4.02 | 4.12 | 3.85 | 3.89 | 1.25M | 0.00% |
| 2026-09-04 | 3.53 | 4.05 | 3.53 | 3.89 | 2.23M | +9.12% |
| 2026-09-03 | 3.71 | 3.74 | 3.46 | 3.56 | 812K | -4.93% |
| 2026-09-02 | 3.45 | 3.77 | 3.45 | 3.75 | 722K | +9.01% |
| 2026-09-01 | 3.24 | 3.57 | 3.17 | 3.44 | 589K | +6.17% |
| 2026-08-31 | 3.17 | 3.28 | 3.05 | 3.24 | 465K | +0.31% |
| 2026-08-28 | 3.32 | 3.38 | 3.21 | 3.23 | 212K | -2.71% |
| 2026-08-27 | 3.31 | 3.37 | 3.25 | 3.32 | 397K | -0.60% |
| 2026-08-26 | 3.03 | 3.35 | 3.00 | 3.34 | 627K | +9.15% |
| 2026-08-25 | 2.96 | 3.09 | 2.94 | 3.06 | 422K | +3.38% |
| 2026-08-24 | 3.02 | 3.07 | 2.83 | 2.96 | 838K | -3.90% |
| 2026-08-21 | 3.15 | 3.21 | 3.02 | 3.08 | 682K | -1.28% |
| 2026-08-20 | 3.30 | 3.39 | 3.03 | 3.12 | 716K | -7.42% |
| 2026-08-19 | 3.07 | 3.50 | 3.06 | 3.37 | 1.04M | +12.71% |
| 2026-08-18 | 3.03 | 3.13 | 2.97 | 2.99 | 353K | -0.99% |
| 2026-08-17 | 3.03 | 3.09 | 2.83 | 3.02 | 559K | +0.33% |
| 2026-08-14 | 2.99 | 3.08 | 2.86 | 3.01 | 704K | 0.00% |
| 2026-08-13 | 2.95 | 3.35 | 2.75 | 3.01 | 1.27M | -5.35% |
| 2026-08-12 | 2.76 | 3.21 | 2.72 | 3.18 | 1.94M | +12.37% |
| 2026-08-11 | 3.85 | 4.00 | 1.90 | 2.83 | 12.12M | -26.11% |
| 2026-08-10 | 3.72 | 3.99 | 3.72 | 3.83 | 999K | +2.68% |
| 2026-08-07 | 3.78 | 3.90 | 3.62 | 3.73 | 1.24M | -0.53% |
| 2026-08-06 | 3.14 | 3.77 | 3.13 | 3.75 | 1.40M | +19.81% |
| 2026-08-05 | 3.20 | 3.32 | 3.07 | 3.13 | 669K | -0.95% |
| 2026-08-04 | 3.02 | 3.25 | 3.02 | 3.16 | 926K | +3.95% |
| 2026-08-03 | 2.70 | 3.05 | 2.70 | 3.04 | 1.14M | +14.72% |
| 2026-07-31 | 2.84 | 2.85 | 2.63 | 2.65 | 750K | -7.67% |
| 2026-07-30 | 2.95 | 3.00 | 2.81 | 2.87 | 638K | -1.71% |
| 2026-07-29 | 2.90 | 3.09 | 2.89 | 2.92 | 945K | +0.34% |
| 2026-07-28 | 2.90 | 3.05 | 2.74 | 2.91 | 1.73M | 0.00% |
| 2026-07-27 | 2.64 | 2.99 | 2.62 | 2.91 | 988K | +11.49% |
| 2026-07-24 | 2.72 | 2.83 | 2.60 | 2.61 | 855K | -2.61% |
PYXS Chart Terminal
Live VCP patterns, Cup & Handle overlays, support/resistance, and AI trade plans.
Live Breakouts Feed
High-probability breakout stocks crossing their pivot across 5 pattern engines.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
PYXS — Frequently Asked Questions
Quick answers to the most common questions about buying PYXS stock.
How has PYXS stock performed recently?
PYXS declined -4.9% over the past year, below its 5-year annualized CAGR of -30.5%. The stock trades above its 200-day moving average, reflecting the downtrend.
What is PYXS's all-time high price?
Pyxis Oncology, Inc. reached $19.00 on 2021-10-08. The 52-week high is $5.55. Current 1-year return of -4.9% places the stock further from historical peaks.
Where can I download PYXS historical price data?
This page provides PYXS daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2021-2026, downloadable in CSV format.