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TPSTTempest Therapeutics, Inc.
$1.23$5M
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TPST logoTempest Therapeutics, Inc.(TPST)Earnings, Financials & Key Ratios

TPST•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutTempest Therapeutics Inc., a clinical-stage oncology company, engages in developing small molecule therapeutics to treat cancer. The company's two clinical programs are TPST-1495, a dual antagonist of EP2 and EP4, receptors of prostaglandin E2, and is currently in a Phase 1 trial in solid tumors; and TPST-1120, a selective antagonist of peroxisome proliferator-activated receptor alpha that is in a Phase 1 trial in solid tumors. It also develops TREX-1, a key cellular enzyme that regulates the innate immune response in tumors. The company was founded in 2011 and is headquartered in South San Francisco, California. Tempest Therapeutics Inc. was formerly a subsidiary of Inception Sciences, Inc.Show more
  • Revenue$0
  • EBITDA-$26M+36.8%
  • Net Income-$26M+37.2%
  • EPS (Diluted)-6.33-322.0%
  • ROE-203.63%-11.7%

TPST Key Insights

Tempest Therapeutics, Inc. (TPST) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Share count reduced 85.1% through buybacks
  • ✓Trading at only 0.8x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Weak momentum: RS Rating 4 (bottom 4%)
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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TPST Price & Volume

Tempest Therapeutics, Inc. (TPST) stock price & volume — 10-year historical chart

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TPST Growth Metrics

Tempest Therapeutics, Inc. (TPST) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM3.8%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-38.31%

Return on Capital

10 Years-73.84%
5 Years-94.47%
3 Years-107.67%
Last Year-130%

TPST Recent Earnings

Tempest Therapeutics, Inc. (TPST) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)
Q2 2026Latest
May 15, 2026
Metric
Actual
Est
EPS
$2.53-803.6%
$0.28
Rev
—
—
Q2 2026
Mar 31, 2026
Metric
Actual
Est
EPS
$0.62+0.0%
$0.62
Rev
—
—
Q4 2025
Nov 5, 2025
Metric
Actual
Est
EPS
$0.79+75.8%
$3.27
Rev
—
—
Q3 2025
Aug 11, 2025
Metric
Actual
Est
EPS
$2.07+35.9%
$3.23
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 15, 2026
$2.53vs $0.28-803.6%
—
Q2 2026Mar 31, 2026
$0.62vs $0.62+0.0%
—
Q4 2025Nov 5, 2025
$0.79vs $3.27+75.8%
—
Q3 2025Aug 11, 2025
$2.07vs $3.23+35.9%
—
Based on last 12 quarters of dataView full earnings history →

TPST Peer Comparison

Tempest Therapeutics, Inc. (TPST) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IMVT logoIMVTImmunovant, Inc.Direct Competitor7.26B35.34-12.76-68.16%0.00
AGEN logoAGENAgenus Inc.Direct Competitor124.93M3.00-882.3510.37%52.16%
AGIO logoAGIOAgios Pharmaceuticals, Inc.Direct Competitor2.03B34.16-4.8048.03%-6.4%-34.11%0.05
RCUS logoRCUSArcus Biosciences, Inc.Product Competitor2.45B24.31-7.39-4.26%-156.36%-68.97%0.16
NKTR logoNKTRNektar TherapeuticsProduct Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
FATE logoFATEFate Therapeutics, Inc.Product Competitor243.61M2.09-1.82-51.24%-20.57%-58.89%0.38
MGNX logoMGNXMacroGenics, Inc.Product Competitor262.52M4.13-3.500.78%-44.79%-147.8%1.92
CRIS logoCRISCuris, Inc.Product Competitor81.52M0.42-0.73-13.43%-299.66%-138.81%0.30

Compare TPST vs Peers

Tempest Therapeutics, Inc. (TPST) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for TPST.

Scale Benchmark

vs MRK

Larger-name benchmark to compare TPST against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, AGEN, AGIO, RCUS

TPST Income Statement

Tempest Therapeutics, Inc. (TPST) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
295K000000000
Revenue Growth %
-54.82%-100%--------
Cost of Goods Sold
28K32K0815K000389K022.25M
COGS % of Revenue
9.49%---------
Gross Profit
267K▲ 0%
-32K▼ 112.0%
-1.05M▼ 3187.5%
-815K▲ 22.5%
0▲ 100.0%
0▲ 0%
0▲ 0%
-389K▲ 0%
0▲ 100.0%
-22.25M▲ 0%
Gross Margin %
90.51%---------
Gross Profit Growth %
105.62%-111.98%-3187.5%22.53%100%---100%-
Operating Expenses
20.45M23.08M44.35M18.48M26.99M34.64M29.16M41.64M26.57M21.11M
OpEx % of Revenue
6933.56%---------
Selling, General & Admin
5.93M8.66M16.5M4.09M9.82M12.11M11.66M13.55M13.97M16.09M
SG&A % of Revenue
2009.49%---------
Research & Development
14.53M14.43M27.84M14.39M17.17M22.53M17.5M28.48M12.61M5.09M
R&D % of Revenue
4924.07%---------
Other Operating Expenses
0000000-389K0-67K
Operating Income
-20.48M▲ 0%
-23.12M▼ 12.9%
-45.4M▼ 96.4%
-19.3M▲ 57.5%
-26.99M▼ 39.8%
-34.64M▼ 28.4%
-29.16M▲ 15.8%
-42.03M▼ 44.1%
-26.57M▲ 36.8%
-43.36M▲ 0%
Operating Margin %
-6943.05%---------
Operating Income Growth %
74.72%-12.86%-96.4%57.49%-39.84%-28.36%15.83%-44.14%36.77%-
EBITDA
-20.45M-23.08M-44.35M-18.48M-26.61M-34M-28.78M-41.64M-26.31M-43.16M
EBITDA Margin %
-6933.56%---------
EBITDA Growth %
74.03%-12.86%-92.11%58.32%-43.98%-27.77%15.37%-44.69%36.81%3.27%
D&A (Non-Cash Add-back)
28K32K1.05M815K374K638K381K389K266K198K
EBIT
-84.3M-27.04M-44.57M-19.21M-27.02M-34.09M-28.04M-40.53M-26.05M-43.08M
Net Interest Income
00264K90K-1.28M-1.07M-334K183K313K214K
Interest Income
00264K90K1.28K549K1.11M1.5M520K283K
Interest Expense
0134K001.28M1.62M1.45M1.32M207K69K
Other Income/Expense
-64.1M-4.06M831K90K-1.32M-1.07M-334K183K313K261K
Pretax Income
-84.59M▲ 0%
-27.18M▲ 67.9%
-44.57M▼ 64.0%
-19.21M▲ 56.9%
-28.3M▼ 47.3%
-35.71M▼ 26.2%
-29.49M▲ 17.4%
-41.84M▼ 41.9%
-26.26M▲ 37.2%
-43.1M▲ 0%
Pretax Margin %
-28673.22%---------
Income Tax
67K-169K00000000
Effective Tax Rate %
-0.08%0.62%0%0%0%0%0%0%0%0%
Net Income
-84.58M▲ 0%
-27.19M▲ 67.8%
-44.57M▼ 63.9%
-19.12M▲ 57.1%
-28.3M▼ 48.0%
-35.71M▼ 26.2%
-29.49M▲ 17.4%
-41.84M▼ 41.9%
-26.26M▲ 37.2%
-43.1M▲ 0%
Net Margin %
-28670.51%---------
Net Income Growth %
-2.82%67.85%-63.9%57.1%-48.04%-26.17%17.41%-41.88%37.24%3.8%
Net Income (Continuing)
-84.59M-27.18M-44.57M-19.21M-28.3M-35.71M-29.49M-41.84M-26.26M-43.1M
Discontinued Operations
0000000000
Minority Interest
12.76M2.17M1.32M0000000
EPS (Diluted)
-72406.33▲ 0%
-263.65▲ 99.6%
-48.77▲ 81.5%
-612.56▼ 1156.0%
-7.80▲ 98.7%
-3.18▲ 59.2%
-1.91▲ 39.9%
-1.50▲ 21.5%
-6.33▼ 322.0%
-3.94▲ 0%
EPS Growth %
-12476.44%99.64%81.5%-1156.02%98.73%59.23%39.94%21.47%-322%-38.31%
EPS (Basic)
-72406.33-263.65-48.77-612.56-7.80-3.18-1.91-1.50-6.33-
Diluted Shares Outstanding
1.17K103.14K913.78K31.21K291.56K888.38K15.42M27.9M4.15M10.93M
Basic Shares Outstanding
1.17K103.14K913.78K31.21K291K888K15.42M27.9M4.15M10.93M
Dividend Payout Ratio
----------

TPST Balance Sheet

Tempest Therapeutics, Inc. (TPST) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
19.74M83.42M71.13M19.82M68.96M32.95M40.36M31.47M8.27M2.45M
Cash & Short-Term Investments
67.2M77.72M63.51M18.82M51.83M31.23M39.23M30.27M7.71M1.8M
Cash Only
15.7M73.33M63.51M18.82M51.83M31.23M39.23M30.27M7.71M1.8M
Short-Term Investments
51.5M4.38M00000000
Accounts Receivable
1.03M2.33M1.28M260K15M450K0000
Days Sales Outstanding
1.28K---------
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
1.58M3.37M6.34M59K553K263K96K535K562K641K
Total Non-Current Assets
74K652K3.84M3.04M4.28M13.14M11.24M10.01M8.66M8.3M
Property, Plant & Equipment
3.11M03.33M2.99M4.16M12.71M10.79M9.53M8.14M7.79M
Fixed Asset Turnover
0.09x--------0.00x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
146K439K00000388K0388K
Other Non-Current Assets
-3.19M213K507K51K111K429K448K97K517K509K
Total Assets
19.81M▲ 0%
84.07M▲ 324.4%
74.97M▼ 10.8%
22.86M▼ 69.5%
73.24M▲ 220.3%
46.09M▼ 37.1%
51.6M▲ 12.0%
41.49M▼ 19.6%
16.93M▼ 59.2%
10.75M▲ 0%
Asset Turnover
0.01x--------0.00x
Asset Growth %
-83.83%324.36%-10.83%-69.5%220.33%-37.07%11.96%-19.6%-59.19%-217.09%
Total Current Liabilities
4.09M9.82M12.52M3.22M20.03M7.28M9.41M14.22M3.31M3.31M
Accounts Payable
2.24M2M1.5M1.07M991K1.11M845K2.45M1.04M585K
Days Payables Outstanding
29.23K22.79K-479.65---2.3K-29.78
Short-Term Debt
174K189K1.96M0004.29M6.35M1.19M1.24M
Deferred Revenue (Current)
334K000000000
Other Current Liabilities
2.29M7.63M7.02M774K912K1.25M1.79M01.08M1.49M
Current Ratio
4.82x8.50x5.68x6.15x3.44x4.53x4.29x2.21x2.50x0.74x
Quick Ratio
4.82x8.50x5.68x6.15x3.44x4.53x4.29x2.21x2.50x0.74x
Cash Conversion Cycle
----------
Total Non-Current Liabilities
738K1.14M2.58M88.43M17.09M20.7M15.42M8.14M6.95M6.62M
Long-Term Debt
599K383K168K015.07M10.37M6.26M06.95M6.62M
Capital Lease Obligations
002.4M1.73M2.03M10.33M9.16M8.14M014.82M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
139K752K16K86.71M000000
Total Liabilities
4.83M10.95M15.1M91.66M37.12M27.98M24.84M22.36M10.26M9.93M
Total Debt
773K572K4.52M2.44M18.54M22.11M20.66M15.37M8.14M7.85M
Net Debt
-16.85M-72.76M-58.99M-16.38M-33.29M-9.12M-18.57M-14.9M434K6.05M
Debt / Equity
0.05x0.01x0.08x-0.51x1.22x0.77x0.80x1.22x9.55x
Debt / EBITDA
----------0.18x
Net Debt / EBITDA
----------0.14x
Interest Coverage
--201.81x---21.08x-21.07x-19.35x-30.80x-125.87x-624.28x
Total Equity
14.98M▲ 0%
73.12M▲ 388.0%
59.87M▼ 18.1%
-68.79M▼ 214.9%
36.12M▲ 152.5%
18.11M▼ 49.9%
26.77M▲ 47.8%
19.13M▼ 28.5%
6.67M▼ 65.1%
822K▲ 0%
Equity Growth %
-86.15%388.03%-18.12%-214.9%152.5%-49.85%47.8%-28.55%-65.14%-244.61%
Book Value per Share
12827.91708.9965.52-2204.20123.8720.391.740.691.610.08
Total Shareholders' Equity
2.23M70.95M58.55M-68.79M36.12M18.11M26.77M19.13M6.67M822K
Common Stock
36K13K18K1K7K11K22K44K5K14K
Retained Earnings
-136.89M-164.09M-208.65M-71.76M-100.06M-135.77M-165.26M-207.11M-233.37M-270.07M
Treasury Stock
0000000000
Accumulated OCI
-19K148K165K0000000
Minority Interest
12.76M2.17M1.32M0000000

TPST Cash Flow Statement

Tempest Therapeutics, Inc. (TPST) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-20.34M-23.65M-41.22M-19.02M-25.96M-31.07M-27.36M-33.03M-26.82M-26.38M
Operating CF Margin %
-6894.92%---------
Operating CF Growth %
67.05%-16.26%-74.32%53.87%-36.49%-19.71%11.96%-20.73%18.79%50.64%
Net Income
-84.58M-27.19M-44.57M-19.21M-28.3M-35.71M-29.49M-41.84M-26.26M-43.1M
Depreciation & Amortization
1.65M32K1.05M339K374K638K381K389K266K258K
Stock-Based Compensation
6.89M1.43M0453K1.1M1.56M2.55M5.3M3.12M1.96M
Deferred Taxes
0000000000
Other Non-Cash Items
66.05M04.35M470K1.48M1.57M1.88M1.51M1.19M21.1M
Working Capital Changes
-1.84M1.04M-2.05M-1.07M-613K868K-2.68M1.61M-5.13M-6.6M
Change in Receivables
0000000000
Change in Inventory
0000000000
Change in Payables
-1.45M320K-469K-574K-209K1K-263K1.6M-1.41M-1.6M
Cash from Investing
458K1.12M3.99M-6K-97K-562K-170K-435K00
Capital Expenditures
-158K-36K-397K-50K-135K-562K-170K-435K00
CapEx % of Revenue
53.56%---------
Acquisitions
0-1.33M00000000
Investments
----------
Other Investing
-1.45M0044K38K00000
Cash from Financing
-4.46M78.55M26.94M34.6M59.06M11.4M35.6M24.5M4.26M6.68M
Debt Issued (Net)
-4.46M6.48M-202K015M-4.74M0-4.4M-6.43M-4.23M
Equity Issued (Net)
2K38.76M27.14M35M33.42M16.14M35.6M28.59M10.69M9.05M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
033.32M0-401K10.64M00307K01.86M
Net Change in Cash
-26.31M▲ 0%
55.71M▲ 311.8%
-9.82M▼ 117.6%
15.58M▲ 258.6%
33.01M▲ 111.9%
-20.23M▼ 161.3%
8.07M▲ 139.9%
-8.96M▼ 211.0%
-22.56M▼ 151.7%
-19.71M▲ 0%
Free Cash Flow
-20.34M▲ 0%
-23.68M▼ 16.4%
-41.62M▼ 75.7%
-19.07M▲ 54.2%
-26.09M▼ 36.8%
-31.63M▼ 21.2%
-27.53M▲ 13.0%
-33.46M▼ 21.6%
-26.82M▲ 19.8%
-26.38M▲ 0%
FCF Margin %
-6896.27%---------
FCF Growth %
68.37%-16.41%-75.73%54.19%-36.84%-21.24%12.98%-21.56%19.85%22.73%
FCF per Share
-17417.81-229.63-45.55-610.93-89.49-35.61-1.79-1.20-6.46-2.41
FCF Conversion (FCF/Net Income)
0.24x0.87x0.92x0.99x0.92x0.87x0.93x0.79x1.02x0.61x
Interest Paid
000001.54M1.25M1.18M192K44K
Taxes Paid
0000018K191K54K43K43K

TPST Key Ratios

Tempest Therapeutics, Inc. (TPST) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-137.3%-61.73%-67.02%--78.36%-131.7%-131.42%-182.35%-203.63%-729.89%
Return on Invested Capital (ROIC)
-47.75%-8335.1%-5474.16%---439.59%-254.36%-507.48%-351.99%-512.6%
Gross Margin
90.51%---------
Net Margin
-28670.51%---------
Debt / Equity
0.05x0.01x0.08x-0.51x1.22x0.77x0.80x1.22x9.55x
Interest Coverage
--201.81x---21.08x-21.07x-19.35x-30.80x-125.87x-624.28x
FCF Conversion
0.24x0.87x0.92x0.99x0.92x0.87x0.93x0.79x1.02x0.61x
Revenue Growth
-54.82%-100%--------
Related:TPST Dividend History·TPST Revenue History·TPST Price History·TPST P/E History·TPST Financial Ratios·TPST Institutional Holders

TPST SEC Filings & Documents

Tempest Therapeutics, Inc. (TPST) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 22, 2026·SEC

Material company update

May 22, 2026·SEC

Material company update

May 14, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 30, 2026·SEC

FY 2025

Mar 27, 2025·SEC

FY 2024

Mar 19, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 11, 2025·SEC

TPST Frequently Asked Questions

Tempest Therapeutics, Inc. (TPST) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Tempest Therapeutics, Inc. (TPST) grew revenue by 0.0% over the past year. Growth has been modest.

Tempest Therapeutics, Inc. (TPST) reported a net loss of $43.1M for fiscal year 2025.

Dividend & Returns

Tempest Therapeutics, Inc. (TPST) has a return on equity (ROE) of -203.6%. Negative ROE indicates the company is unprofitable.

Tempest Therapeutics, Inc. (TPST) had negative free cash flow of $26.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TPST back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

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