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RPTXRepare Therapeutics Inc.
$2.65$114M
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Repare Therapeutics Inc. (RPTX) Financial Ratios

Latest Ratios: P/E Ratio -1.3x · EV/EBITDA N/A · ROE -46.6%. (2018–2024 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

RPTX Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Market Cap$114M$56M$307M$617M$798M$1.3B——
Enterprise Value$31M$-27225479$199M$463M$470M$944M——
P/E Ratio →-1.32———————
P/S Ratio2.141.046.014.68104.959376.08——
P/B Ratio0.740.371.452.212.774.41——
P/FCF————————
P/OCF———1915.13————

P/E links to full P/E history page with 30-year chart

RPTX EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
EV / Revenue—-0.513.903.5161.906989.57——
EV / EBITDA————————
EV / EBIT————————
EV / FCF————————

RPTX Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Gross Margin75.0%75.0%74.1%11.5%-1056.0%-28622.2%——
Operating Margin-174.9%-174.9%-227.3%-15.0%-1429.7%-40223.7%——
Net Profit Margin-158.4%-158.4%-183.4%-22.0%-1406.7%-39568.1%——

Return on Capital

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
ROE-46.6%-46.6%-38.2%-10.2%-37.2%-28.4%-80.7%—
ROA-39.4%-39.4%-30.4%-7.9%-29.5%-23.2%-46.7%-102.6%
ROIC-81.3%-81.3%-75.9%-34.2%————
ROCE-51.1%-51.1%-46.5%-6.4%-32.0%-24.4%-46.7%-106.7%

RPTX Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Debt / Equity0.010.010.020.020.030.010.01—
Debt / EBITDA————————
Net Debt / Equity—-0.55-0.51-0.55-1.13-1.12-1.04—
Net Debt / EBITDA————————
Debt / FCF————————
Interest Coverage————————

Net cash position: cash ($85M) exceeds total debt ($2M)

RPTX Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Current Ratio6.776.776.244.5010.0131.4623.226.32
Quick Ratio6.776.776.244.5010.0131.4623.226.32
Cash Ratio6.046.045.724.379.7430.3022.335.63
Asset Turnover—0.300.200.360.020.00——
Inventory Turnover————————
Days Sales Outstanding—84.27109.3011.97155.3216665.63——

RPTX Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Dividend Yield————————
Payout Ratio————————

Total Shareholder Return Metrics

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018
Earnings Yield————————
FCF Yield————————
Buyback Yield0.0%0.0%0.0%0.0%0.0%0.0%——
Total Shareholder Yield0.0%0.0%0.0%0.0%0.0%0.0%——
Shares Outstanding—$42M$42M$42M$38M$37M$37M$16M

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Clinical milestone funding dependency

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2025Q3)

Market Pricing Reflects Pipeline Uncertainty

Based on reported figures, RPTX trades at a P/S multiple of 2.14, which appears to discount the company's platform potential significantly compared to peers like Revolution Medicine, suggesting that investors are pricing in the high probability of future dilutive capital raises to sustain clinical operations.

The current valuation reflects a market that is increasingly skeptical of the company's ability to generate independent value following the termination of key partnerships. Without recurring revenue or a clear path to commercialization, traditional multiples like P/E are non-meaningful, leaving the stock tethered to the speculative value of its DNA damage repair pipeline.

Capital Compounding Remains Deeply Negative

As reported in financial statements, the company's ROIC has fluctuated wildly, reaching a low of -37.8% in 2025Q1, which indicates that the capital deployed into the SNIPRx platform has yet to generate a positive return, reflecting the inherent inefficiency of pre-revenue clinical-stage biotechnology development.

The negative ROIC trend highlights the massive capital intensity required to advance clinical assets without the offset of commercial product sales. Investors should monitor whether the company can improve these returns through more selective pipeline prioritization or if the current burn rate will continue to erode shareholder value.

Working Capital Volatility Hinders Efficiency

According to recent SEC filings, the company's asset turnover ratio remains negligible at 0.09 in 2025Q3, underscoring the lack of operational scale and the reliance on non-recurring milestone payments rather than a consistent, high-velocity revenue generation model typical of mature industrial or technology firms.

The extreme fluctuations in DSO, which reached 21,344 in 2025Q2, suggest that the timing of milestone collections is highly irregular and unpredictable. This lack of working capital efficiency forces the company to maintain higher cash buffers, further complicating the management of its limited liquidity position.

Liquidity Buffer Faces Sustained Pressure

Based on reported figures, the current ratio of 10.71 in 2025Q3 appears superficially strong, yet this liquidity is rapidly being consumed by operating losses, leaving the company with a tightening runway that warrants further investigation into the necessity of near-term equity financing to maintain operations.

While the high current ratio suggests an ability to meet short-term obligations, the absence of recurring cash inflows means that the company is essentially living off its remaining cash reserves. The rapid decline in total assets over the last two years indicates that the company is effectively liquidating its balance sheet to fund R&D.

Misapplied Metrics Obscure True Burn

The most commonly misapplied metric for Repare is the gross margin, which, at 100% in 2025Q3, creates a false impression of profitability that ignores the massive, non-capitalized R&D expenses required to sustain the business model, thereby obscuring the company's true underlying cash-burn trajectory.

Investors should instead focus on the cash-burn rate and the cash runway ratio, as these metrics provide a more accurate assessment of the company's survival horizon. Relying on accounting-based margins in a pre-revenue biotech context is misleading, as it fails to account for the massive investment in clinical trials that are expensed immediately.

Download Financial Ratios Data

Includes 30+ ratios · 7 years · Updated daily

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RPTX — Frequently Asked Questions

Quick answers to the most common questions about buying RPTX stock.

What is Repare Therapeutics Inc.'s P/E ratio?

Repare Therapeutics Inc.'s current P/E ratio is -1.3x. This places it at the 50th percentile of its historical range.

What is Repare Therapeutics Inc.'s ROE?

Repare Therapeutics Inc.'s return on equity (ROE) is -46.6%. The historical average is -40.2%.

Is RPTX stock overvalued?

Based on historical data, Repare Therapeutics Inc. is trading at a P/E of -1.3x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.

What are Repare Therapeutics Inc.'s profit margins?

Repare Therapeutics Inc. has 75.0% gross margin and -174.9% operating margin.