Last 25 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -1.32 | 5.50 | — | — | — | — | — | 3.93 | — | — | — | — | — | 1.77 | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 2.14 | 1.63 | 59.66 | — | — | — | 32.64 | 0.99 | 5.89 | 58.89 | 3.68 | 18.21 | 8.49 | 1.19 | 215.82 | 365.26 | 30.80 | 875.99 | 1034.77 | 1706.29 | 2336.39 |
| — | — | +82.8% | — | — | — | +786.7% | -94.6% | -30.6% | +4847.5% | -98.3% | -95.0% | -72.4% | -99.9% | -79.1% | -78.6% | -98.7% | — | — | — | — | |
| P/B Ratio | 0.74 | 0.66 | 0.54 | 0.34 | 0.37 | 0.83 | 0.69 | 0.89 | 1.45 | 2.18 | 1.81 | 1.65 | 2.21 | 1.75 | 2.60 | 2.30 | 2.94 | 4.46 | 4.71 | 4.23 | 4.40 |
| — | -21.2% | -21.4% | -62.5% | -74.7% | -61.7% | -62.1% | -45.7% | -34.4% | +24.4% | -30.2% | -28.6% | -24.7% | -60.7% | -44.8% | -45.6% | -33.2% | +18.7% | +887.4% | — | — | |
| P/FCF | — | 7.15 | — | — | — | — | — | 4.34 | — | — | — | — | — | 1.52 | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | 0.68 | — | — | — | — | — | 2.36 | — | — | — | — | — | 1.29 | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | 0.24 | — | — | — | — | — | 2.47 | — | — | — | — | — | 1.27 | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 75.0% | 100.0% | 100.0% | — | — | — | 54.5% | 99.0% | 96.1% | 51.4% | 96.5% | 82.7% | -51.4% | 99.1% | -57.6% | -6384.8% | -274.9% | -9022.7% | -7141.9% | -9845.2% | -8123.0% |
| — | — | +83.4% | — | — | — | -43.5% | +19.8% | +287.1% | -48.1% | +267.6% | +101.3% | +81.3% | +101.1% | +99.2% | +35.1% | +96.6% | — | — | — | — | |
| Operating Margin | -174.9% | 9.7% | -7112.0% | — | — | — | -3453.8% | 20.6% | -233.4% | -1765.3% | -39.3% | -604.1% | -107.9% | 65.5% | -5656.4% | -8536.5% | -417.8% | -11395.3% | -9558.1% | -13000.0% | -12649.6% |
| — | — | -105.9% | — | — | — | -8683.7% | +103.4% | -116.3% | -2795.5% | +99.3% | +92.9% | +74.2% | +100.6% | +40.8% | +34.3% | +96.7% | — | — | — | — | |
| Net Margin | -158.4% | 28.0% | -6697.6% | — | — | — | -3240.8% | 25.1% | -214.8% | -874.4% | -39.5% | -615.4% | -174.0% | 67.0% | -5610.2% | -8518.9% | -411.4% | -11112.2% | -9429.7% | -12901.8% | -11305.9% |
| — | — | -106.7% | — | — | — | -8106.2% | +104.1% | -23.5% | -1404.2% | +99.3% | +92.8% | +57.7% | +100.6% | +40.5% | +34.0% | +96.4% | — | — | — | — |
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -46.6% | 2.9% | -14.2% | -21.8% | -17.6% | -18.2% | -16.0% | 5.9% | -12.6% | -7.9% | -4.8% | -13.2% | -10.8% | 28.4% | -15.7% | -12.7% | -11.2% | -13.3% | -10.3% | -7.7% | -5.2% |
| — | +115.9% | +10.9% | -466.9% | -39.7% | -130.4% | -231.9% | +145.0% | -16.3% | -127.8% | +69.4% | -3.6% | +3.1% | +313.0% | -53.3% | -64.5% | -115.0% | -197.9% | -70.2% | +48.6% | +69.0% | |
| ROA | -39.4% | 2.5% | -12.2% | -18.7% | -15.0% | -15.6% | -14.0% | 5.1% | -10.4% | -6.4% | -3.7% | -10.0% | -8.2% | 21.0% | -11.8% | -9.8% | -8.5% | -10.0% | -8.0% | -6.2% | -4.2% |
| — | +116.3% | +12.6% | -468.2% | -44.3% | -142.6% | -272.6% | +151.0% | -26.7% | -130.5% | +68.3% | -1.3% | +3.9% | +309.9% | -48.1% | -60.1% | -102.9% | -174.1% | -60.6% | +52.1% | +48.3% | |
| ROIC | -81.3% | 2.0% | -31.2% | -37.8% | -27.8% | -23.3% | -21.6% | 6.9% | -19.5% | -21.6% | -6.6% | -19.8% | -10.4% | 98.0% | — | — | — | — | — | — | — |
| — | +108.5% | -44.7% | -648.8% | -42.6% | -7.6% | -225.7% | +134.8% | -86.7% | -122.1% | — | — | — | — | — | — | — | — | — | — | — |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.01 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.03 | 0.03 | 0.03 | 0.03 | 0.02 | 0.01 | 0.01 |
| — | -79.7% | -45.0% | -8.5% | -20.5% | -12.9% | -42.4% | -40.2% | -17.2% | -12.8% | -37.0% | -26.0% | -23.4% | -40.6% | +67.6% | +90.8% | +81.6% | +140.8% | +639.3% | +25.2% | +17.9% | |
| Debt / EBITDA | — | 0.28 | — | — | — | — | — | 0.25 | — | — | — | — | — | 0.08 | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 6.77 | 10.71 | 6.30 | 7.42 | 6.77 | 6.45 | 7.27 | 8.33 | 6.24 | 5.62 | 5.48 | 4.02 | 4.50 | 6.31 | 7.35 | 9.37 | 10.01 | 11.98 | 13.31 | 26.43 | 31.46 |
| — | +66.1% | -13.3% | -11.0% | +8.5% | +14.8% | +32.6% | +107.1% | +38.5% | -11.0% | -25.4% | -57.1% | -55.0% | -47.3% | -44.8% | -64.6% | -68.2% | -66.2% | -65.4% | +119.7% | +35.5% | |
| Quick Ratio | 6.77 | 10.71 | 6.30 | 7.42 | 6.77 | 6.55 | 7.27 | 8.33 | 6.24 | 5.62 | 5.48 | 4.02 | 4.50 | 6.31 | 7.35 | 9.37 | 10.01 | 11.98 | 13.31 | 26.43 | 31.46 |
| — | +63.4% | -13.3% | -11.0% | +8.5% | +16.6% | +32.6% | +107.1% | +38.5% | -11.0% | -25.4% | -57.1% | -55.0% | -47.3% | -44.8% | -64.6% | -68.2% | -66.2% | -65.4% | +119.7% | +35.5% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
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Includes 30+ ratios · 25 years · Updated daily
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Quick answers to the most common questions about buying RPTX stock.
Repare Therapeutics Inc.'s current P/E is -1.3x. The average P/E over the last 1 quarters is 5.5x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Repare Therapeutics Inc.'s current operating margin is -174.9%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Repare Therapeutics Inc.'s business trajectory between earnings reports.