Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in RZLT held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | 13.0M | $39.6M | -21.4% | 13.491% | 0.06% |
| 2 | RA CAPITAL MANAGEMENT, L.P. | 9.2M | $28.0M | 0.0% | 9.534% | 0.30% |
| 3 | BlackRock, Inc. | 6.3M | $19.3M | -6.7% | 6.557% | 0.00% |
| 4 | Opaleye Management Inc. | 6.3M | $19.2M | +0.2% | 6.543% | 2.53% |
| 5 | BALYASNY ASSET MANAGEMENT LLC | 5.0M | $15.4M | +12.0% | 5.243% | 0.05% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 3.5M | $10.7M | β | 3.658% | 0.00% |
| 7 | JENNISON ASSOCIATES LLC | 3.4M | $10.5M | β | 3.571% | 0.01% |
| 8 | Siren, L.L.C. | 3.3M | $10.2M | β | 3.456% | 0.28% |
| 9 | VANGUARD PORTFOLIO MANAGEMENT LLC | 3.0M | $9.1M | β | 3.097% | 0.00% |
| 10 | BANK OF AMERICA CORP /DE/ | 3.0M | $9.1M | -31.3% | 3.085% | 0.00% |
| 11 | MORGAN STANLEY | 2.7M | $8.4M | +81.2% | 2.853% | 0.00% |
| 12 | Integral Health Asset Management, LLC | 2.0M | $6.1M | 0.0% | 2.077% | 0.38% |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 2.0M | $6.0M | +0.5% | 2.040% | 0.00% |
| 14 | UBS Group AG | 1.9M | $5.9M | -31.2% | 2.013% | 0.00% |
| 15 | STATE STREET CORP | 1.8M | $5.4M | -55.5% | 1.840% | 0.00% |
| 16 | D. E. Shaw & Co., Inc. | 1.8M | $5.4M | +608.1% | 1.834% | 0.01% |
| 17 | Affinity Asset Advisors, LLC | 1.5M | $4.7M | -34.2% | 1.607% | 0.27% |
| 18 | MILLENNIUM MANAGEMENT LLC | 1.5M | $4.6M | -11.3% | 1.576% | 0.00% |
| 19 | KENNEDY CAPITAL MANAGEMENT, INC. | 1.2M | $3.8M | +77.1% | 1.284% | 0.08% |
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.1M | $3.3M | +126.1% | 1.129% | 0.00% |
| 21 | GREAT POINT PARTNERS LLC | 952K | $2.9M | 0.0% | 0.988% | 0.71% |
| 22 | TWO SIGMA INVESTMENTS, LP | 831K | $2.5M | β | 0.863% | 0.00% |
| 23 | 22NW, LP | 821K | $2.5M | 0.0% | 0.852% | 1.72% |
| 24 | AQR CAPITAL MANAGEMENT LLC | 797K | $2.4M | +193.9% | 0.827% | 0.00% |
| 25 | Velan Capital Investment Management LP | 750K | $2.3M | 0.0% | 0.779% | 1.43% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in RZLT β a direct measure of their conviction.
Filings activity in RZLT during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new RZLT position in Q1 2026
Institutions that fully closed their RZLT position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 122 | +4.3% | 68.89% | +13.75 pp | $265M | +25% |
| Q4 2025 | 117 | +4.5% | 55.14% | 144.85 pp | $212M | 74% |
| Q3 2025 | 112 | +23% | 199.99% | +110.10 pp | $819M | +137% |
| Q2 2025 | 91 | +21% | 89.89% | +56.69 pp | $346M | +171% |
| Q1 2025 | 75 | +7.1% | 33.20% | 20.42 pp | $128M | 38% |
| Q4 2024 | 70 | +19% | 53.62% | +6.05 pp | $207M | +13% |
| Q3 2024 | 59 | +13% | 47.57% | +4.06 pp | $183M | +9.3% |
| Q2 2024 | 52 | β | 43.51% | β | $168M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying RZLT stock.
Based on Q1 2026 13F filings, institutional ownership of Rezolute, Inc. stands at 68.9%, held across 122 reporting institutions.
FEDERATED HERMES, INC. is the largest reported institutional holder of RZLT, with approximately 12,990,659 shares worth $0.04B as of Q1 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of RZLT, including MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for RZLT is 72 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
37 institutions opened new positions in RZLT during Q1 2026, while 32 fully exited. 61 added to existing positions and 23 trimmed.
RZLT institutional ownership rose by 13.75 percentage points quarter-over-quarter, with a net change of +5 holders.
The top 10 institutions account for 64.5% of all reported 13F value in RZLT, and the top 25 account for 89.4%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Rezolute, Inc. (RZLT) Institutional Ownership