Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in SAVA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | MARSHALL WACE, LLP | 2.0M | $3.4M | -4.9% | 4.166% | 0.00% |
| 2 | TWO SIGMA INVESTMENTS, LP | 2.0M | $3.4M | +209.6% | 4.117% | 0.00% |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 1.9M | $3.3M | β | 3.997% | 0.00% |
| 4 | BlackRock, Inc. | 1.4M | $2.4M | -0.4% | 2.928% | 0.00% |
| 5 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 749K | $1.3M | -25.1% | 1.551% | 0.00% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 596K | $1.0M | +9.2% | 1.234% | 0.00% |
| 7 | D. E. Shaw & Co., Inc. | 559K | $945K | +19.1% | 1.158% | 0.00% |
| 8 | GMT CAPITAL CORP | 450K | $761K | β | 0.932% | 0.03% |
| 9 | RENAISSANCE TECHNOLOGIES LLC | 327K | $552K | β | 0.676% | 0.00% |
| 10 | GROUP ONE TRADING, L.P. | 303K | $511K | +12.3% | 0.626% | 0.02% |
| 11 | VANGUARD FIDUCIARY TRUST CO | 274K | $463K | β | 0.567% | 0.00% |
| 12 | STATE STREET CORP | 240K | $406K | +13.1% | 0.497% | 0.00% |
| 13 | DIMENSIONAL FUND ADVISORS LP | 240K | $405K | +71.3% | 0.497% | 0.00% |
| 14 | JACOBS LEVY EQUITY MANAGEMENT, INC | 209K | $353K | -15.3% | 0.433% | 0.00% |
| 15 | CANADA PENSION PLAN INVESTMENT BOARD | 189K | $320K | +31.2% | 0.391% | 0.00% |
| 16 | NORTHERN TRUST CORP | 149K | $252K | 0.0% | 0.309% | 0.00% |
| 17 | SIMPLEX TRADING, LLC | 140K | $237K | -19.1% | 0.290% | 0.01% |
| 18 | Connor, Clark & Lunn Investment Management Ltd. | 137K | $231K | +36.1% | 0.283% | 0.00% |
| 19 | Walleye Trading LLC | 135K | $229K | -53.5% | 0.280% | 0.00% |
| 20 | VANGUARD PORTFOLIO MANAGEMENT LLC | 133K | $224K | β | 0.275% | 0.00% |
| 21 | FEDERATED HERMES, INC. | 115K | $195K | +25.8% | 0.238% | 0.00% |
| 22 | Susquehanna Portfolio Strategies, LLC | 101K | $170K | -51.3% | 0.209% | 0.00% |
| 23 | Verition Fund Management LLC | 93K | $158K | +69.9% | 0.193% | 0.00% |
| 24 | MILLENNIUM MANAGEMENT LLC | 73K | $123K | -73.6% | 0.150% | 0.00% |
| 25 | Gallacher Capital Management LLC | 65K | $110K | 0.0% | 0.135% | 0.04% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in SAVA β a direct measure of their conviction.
Filings activity in SAVA during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new SAVA position in Q1 2026
Institutions that fully closed their SAVA position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 98 | 7.5% | 35.44% | 8.19 pp | $23M | 19% |
| Q4 2025 | 106 | +6.0% | 43.63% | 24.56 pp | $28M | 36% |
| Q3 2025 | 100 | +2.0% | 68.19% | +31.53 pp | $43M | +86% |
| Q2 2025 | 98 | 15% | 36.66% | 4.17 pp | $23M | 10% |
| Q1 2025 | 115 | 15% | 40.83% | 54.44 pp | $26M | 57% |
| Q4 2024 | 135 | 12% | 95.27% | 104.72 pp | $61M | 87% |
| Q3 2024 | 154 | +7.7% | 199.99% | +0.00 pp | $475M | +89% |
| Q2 2024 | 143 | β | 199.99% | β | $251M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying SAVA stock.
Based on Q1 2026 13F filings, institutional ownership of Cassava Sciences, Inc. stands at 35.4%, held across 98 reporting institutions.
MARSHALL WACE, LLP is the largest reported institutional holder of SAVA, with approximately 2,012,543 shares worth $0.00B as of Q1 2026.
Yes β 5 widely-followed marquee investors appear among the top 25 institutional holders of SAVA, including TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP, RENAISSANCE TECHNOLOGIES LLC, Susquehanna Portfolio Strategies, LLC, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for SAVA is 50 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
17 institutions opened new positions in SAVA during Q1 2026, while 25 fully exited. 12 added to existing positions and 67 trimmed.
SAVA institutional ownership fell by 8.19 percentage points quarter-over-quarter, with a net change of -8 holders.
The top 10 institutions account for 77.3% of all reported 13F value in SAVA, and the top 25 account for 94.4%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Cassava Sciences, Inc. (SAVA) Institutional Ownership