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SGMO logoSangamo Therapeutics, Inc.(SGMO)Earnings, Financials & Key Ratios

SGMO•NASDAQ
$0.18
$38M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryRNA and Genome Editing Developers
AboutSangamo Therapeutics, Inc., a clinical-stage biotechnology company, focuses on translating science into genomic medicines that transform patients' lives using platform technologies in gene therapy, cell therapy, genome editing, and genome regulation. The company offers zinc finger protein (ZFP), a technology platform for making zinc finger nucleases, which are proteins used in modifying DNA sequences by adding or knocking out specific genes; and ZFP transcription factors proteins used in increasing or decreasing gene expression. It develops SB-525, which is in Phase III AFFINE clinical trial for the treatment of hemophilia A; ST-920, a gene therapy, which is in Phase I/II STAAR clinical trials for the treatment of Fabry disease; and SAR445136, a cell therapy, which is in Phase I/II PRECIZN-1 clinical trials for the treatment of sickle cell disease. The company also develops TX200, chimeric antigen receptor for the treatment of HLA-A2 mismatched kidney transplant rejection; KITE-037, a cell therapy for the treatment of cancer; ST-501 for the treatment of tauopathies; and ST-502 for the treatment of synucleinopathies, including Parkinson's disease and neuromuscular disease. It has collaborative and strategic partnerships with Biogen MA, Inc.; Kite Pharma, Inc.; Pfizer Inc.; Sanofi S.A.; Novartis Institutes for BioMedical Research, Inc.; Shire International GmbH; Dow AgroSciences LLC; Sigma-Aldrich Corporation; Genentech, Inc.; Open Monoclonal Technology, Inc.; F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; and California Institute for Regenerative Medicine. The company was formerly known as Sangamo BioSciences, Inc. and changed its name to Sangamo Therapeutics, Inc. in January 2017. Sangamo Therapeutics, Inc. was incorporated in 1995 and is headquartered in Brisbane, California.Show more
  • Revenue$58M-67.2%
  • EBITDA-$95M+62.4%
  • Net Income-$98M+62.0%
  • EPS (Diluted)-0.49+66.9%
  • Gross Margin100%
  • EBITDA Margin-163.68%-14.6%
  • Operating Margin-179.88%-15.7%
  • Net Margin-169.45%-15.8%
  • ROE-185.39%-35.8%
  • ROIC-178.84%-36.4%
  • Debt/Equity1.34+192.0%
Technical→

SGMO Key Insights

Sangamo Therapeutics, Inc. (SGMO) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 2 (bottom 2%)
  • ✗Sales declining 10.8% over 5 years
  • ✗Shares diluted 15.6% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

SGMO Price & Volume

Sangamo Therapeutics, Inc. (SGMO) stock price & volume — 10-year historical chart

Loading chart...

SGMO Growth Metrics

Sangamo Therapeutics, Inc. (SGMO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years2.34%
5 Years-10.81%
3 Years-19.48%
TTM-37.13%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM19.23%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM41.33%

Return on Capital

10 Years-43.42%
5 Years-60.05%
3 Years-84.95%
Last Year-119.91%

SGMO Recent Earnings

Sangamo Therapeutics, Inc. (SGMO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/12 qtrs (25%)●Beat Revenue 3/12 qtrs (25%)
Q4 2025Latest
Nov 6, 2025
EPS
$0.11
Est $0.03
-266.7%
Revenue
$581,000
Est $40M
-98.6%
Q3 2025
Aug 7, 2025
EPS
$0.08
Est $0.07
-14.3%
Revenue
$18M
Est $34M
-46.8%
Q2 2025
May 12, 2025
EPS
$0.14
Est $0.11
-27.3%
Revenue
$6M
Est $7M
-13.2%
Q2 2025
Mar 17, 2025
EPS
$0.11
Est $0.09
-22.2%
Revenue
$8M
Est $12M
-35.5%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q4 2025LatestNov 6, 2025
$0.11vs $0.03-266.7%
$581,000vs $40M-98.6%
Q3 2025Aug 7, 2025
$0.08vs $0.07-14.3%
$18Mvs $34M-46.8%
Q2 2025May 12, 2025
$0.14vs $0.11-27.3%
$6Mvs $7M-13.2%
Q2 2025Mar 17, 2025
$0.11vs $0.09-22.2%
$8Mvs $12M-35.5%
Based on last 12 quarters of dataView full earnings history →

SGMO Peer Comparison

Sangamo Therapeutics, Inc. (SGMO) competitors in RNA and Genome Editing Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
EDIT logoEDITEditas Medicine, Inc.Direct Competitor310.73M3.18-1.76-100%-5.23%0.66
CRSP logoCRSPCRISPR Therapeutics AGDirect Competitor5.31B55.08-8.51-89.97%-138.57%-30.88%0.21
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.32B32.33-39.92120.01%-57.24%-7.31%0.24
NTLA logoNTLAIntellia Therapeutics, Inc.Direct Competitor1.61B13.85-3.64-100%-61.47%0.14
PRME logoPRMEPrime Medicine, Inc.Direct Competitor615.68M3.41-2.5355.28%-43.42%-178.61%0.96
FATE logoFATEFate Therapeutics, Inc.Product Competitor264.17M2.29-1.99-51.24%-20.51%-65.79%0.38
RCKT logoRCKTRocket Pharmaceuticals, Inc.Product Competitor418.11M3.86-1.92-80.49%0.09
ILMN logoILMNIllumina, Inc.Supply Chain21.66B142.5826.16-0.78%19.43%32.84%0.94

Compare SGMO vs Peers

Sangamo Therapeutics, Inc. (SGMO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs EDIT

Most directly comparable listed peer for SGMO.

Scale Benchmark

vs TMO

Larger-name benchmark to compare SGMO against a more recognizable public peer.

Peer Set

Compare Top 5

vs EDIT, CRSP, BEAM, NTLA

SGMO Income Statement

Sangamo Therapeutics, Inc. (SGMO) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue19.39M36.57M84.45M102.43M118.19M110.7M111.3M176.23M57.8M32.88M
Revenue Growth %-50.96%88.6%130.95%21.29%15.39%-6.34%0.54%58.34%-67.2%-37.13%
Cost of Goods Sold65.62M65.73M114.87M145.92M180.65M012.11M000
COGS % of Revenue338.43%179.75%136.01%142.46%152.84%-10.88%---
Gross Profit
-46.23M▲ 0%
-29.16M▲ 36.9%
-30.41M▼ 4.3%
-43.49M▼ 43.0%
-62.45M▼ 43.6%
110.7M▲ 277.2%
99.19M▼ 10.4%
176.23M▲ 77.7%
57.8M▼ 67.2%
32.88M▲ 0%
Gross Margin %-238.43%-79.75%-36.01%-42.46%-52.84%100%89.12%100%100%100%
Gross Profit Growth %-67.56%36.92%-4.3%-43.01%-43.59%277.25%-10.4%77.67%-67.2%-
Operating Expenses91.95M92.93M161.6M61.69M67.1M294.04M300.47M450.24M161.77M141.9M
OpEx % of Revenue474.23%254.13%191.35%60.22%56.77%265.61%269.97%255.48%279.88%-
Selling, General & Admin26.33M27.2M46.74M61.69M67.1M63.22M62.68M61.17M44.73M36.99M
SG&A % of Revenue135.8%74.38%55.34%60.22%56.77%57.11%56.32%34.71%77.38%-
Research & Development65.62M65.73M114.87M145.92M180.65M230.82M249.9M234.06M111.52M104.91M
R&D % of Revenue338.43%179.75%136.01%142.46%152.84%208.51%224.53%132.81%192.94%-
Other Operating Expenses887K00-145.92M-180.65M0-12.11M155.01M5.52M0
Operating Income
-72.56M▲ 0%
-56.36M▲ 22.3%
-77.15M▼ 36.9%
-105.18M▼ 36.3%
-129.55M▼ 23.2%
-183.34M▼ 41.5%
-201.28M▼ 9.8%
-274M▼ 36.1%
-103.97M▲ 62.1%
-109.03M▲ 0%
Operating Margin %-374.23%-154.13%-91.35%-102.69%-109.61%-165.61%-180.85%-155.48%-179.88%-331.64%
Operating Income Growth %-54.86%22.32%-36.89%-36.33%-23.17%-41.52%-9.79%-36.13%62.06%-
EBITDA-71.56M-54.86M-74.79M-101.25M-123.87M-165.7M-189.17M-251.81M-94.61M-101.17M
EBITDA Margin %-369.09%-150.03%-88.56%-98.85%-104.8%-149.68%-169.97%-142.89%-163.68%-307.75%
EBITDA Growth %-56.02%23.34%-36.32%-35.38%-22.34%-33.77%-14.17%-33.11%62.43%22.06%
D&A (Non-Cash Add-back)997K1.5M2.36M3.93M5.68M17.64M12.11M22.19M9.36M7.85M
EBIT-71.67M-56.36M-77.15M-105.18M-129.55M-183.34M-201.28M-118.99M-98.45M-110.67M
Net Interest Income887K1.79M8.26M9.76M8.78M5.35M9.43M11.1M5.86M3.22M
Interest Income887K1.79M8.26M9.76M8.78M5.35M9.43M11.1M5.86M3.22M
Interest Expense0000000000
Other Income/Expense887K1.79M8.26M9.76M8.77M5.35M9.43M11.1M5.86M-325K
Pretax Income
-71.67M▲ 0%
-54.57M▲ 23.9%
-68.89M▼ 26.2%
-95.42M▼ 38.5%
-120.78M▼ 26.6%
-177.99M▼ 47.4%
-191.85M▼ 7.8%
-262.9M▼ 37.0%
-98.11M▲ 62.7%
-109.35M▲ 0%
Pretax Margin %-369.65%-149.23%-81.57%-93.16%-102.19%-160.79%-172.37%-149.18%-169.74%-332.63%
Income Tax-14K000345K306K429K-5.07M-167K-442K
Effective Tax Rate %0.02%0%0%0%-0.29%-0.17%-0.22%1.93%0.17%0.4%
Net Income
-71.66M▲ 0%
-54.57M▲ 23.8%
-68.33M▼ 25.2%
-95.19M▼ 39.3%
-121M▼ 27.1%
-178.29M▼ 47.3%
-192.28M▼ 7.8%
-257.83M▼ 34.1%
-97.94M▲ 62.0%
-108.91M▲ 0%
Net Margin %-369.58%-149.23%-80.91%-92.93%-102.37%-161.05%-172.76%-146.3%-169.45%-331.28%
Net Income Growth %-76.05%23.85%-25.23%-39.3%-27.12%-47.35%-7.85%-34.09%62.01%19.23%
Net Income (Continuing)-71.66M-54.57M-68.89M-95.42M-121.12M-178.3M-192.28M-257.83M-97.94M-108.91M
Discontinued Operations0000000000
Minority Interest00739K185K-868K00000
EPS (Diluted)
-1.02▲ 0%
-0.70▲ 31.4%
-0.70▲ 0.0%
-0.68▲ 2.9%
-0.90▼ 32.4%
-1.23▼ 36.7%
-1.25▼ 1.6%
-1.48▼ 18.4%
-0.49▲ 66.9%
-0.36▲ 0%
EPS Growth %-75.86%31.37%0%2.86%-32.35%-36.67%-1.63%-18.4%66.89%41.33%
EPS (Basic)-1.02-0.70-0.70-0.68-0.90-1.23-1.25-1.48-0.49-
Diluted Shares Outstanding70.55M78.08M96.94M112.11M134.45M144.57M154.34M174.44M201.7M304.27M
Basic Shares Outstanding70.55M78.08M96.94M112.11M134.45M144.57M154.34M174.44M201.7M304.27M
Dividend Payout Ratio----------

SGMO Balance Sheet

Sangamo Therapeutics, Inc. (SGMO) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets149.58M248.4M410.52M405.47M659.67M398.77M300.33M94.33M51.69M44.08M
Cash & Short-Term Investments142.76M244.56M400.51M362.47M641.42M376.55M277.63M81M41.92M30.53M
Cash Only22.06M49.83M140.42M80.43M131.33M178.87M100.44M45.2M41.92M30.53M
Short-Term Investments120.47M193.48M259.71M282.05M510.09M197.68M177.19M35.8M00
Accounts Receivable5.2M3.58M5.05M37.59M6.26M6.36M4.47M4.07M4.6M5.13M
Days Sales Outstanding97.8235.7621.82133.9519.3320.9814.678.4229.0453.59
Inventory-224K-1.25M-375K0000000
Days Inventory Outstanding----------
Other Current Assets01.51M5.34M00009.26M5.17M8.42M
Total Non-Current Assets8.31M38.34M179.87M232.04M278.88M323.15M262.18M70.99M49.94M44.57M
Property, Plant & Equipment6.56M31.07M78.72M107.22M112.37M124.7M125.53M52.87M34.76M29.22M
Fixed Asset Turnover2.96x1.18x1.07x0.96x1.05x0.89x0.89x3.33x1.66x1.03x
Goodwill1.58M1.58M40.04M39.27M42.8M39.7M37.55M000
Intangible Assets0054.87M53.16M58.13M53.76M50.73M000
Long-Term Investments01.01M-6.71M21.83M50.53M88.17M29.84M1.5M1.5M4.5M
Other Non-Current Assets169K4.68M6.24M10.57M15.06M16.82M12.25M16.63M13.69M58.63M
Total Assets
157.89M▲ 0%
286.74M▲ 81.6%
590.39M▲ 105.9%
637.52M▲ 8.0%
938.55M▲ 47.2%
721.92M▼ 23.1%
562.51M▼ 22.1%
165.32M▼ 70.6%
101.64M▼ 38.5%
88.64M▲ 0%
Asset Turnover0.12x0.13x0.14x0.16x0.13x0.15x0.20x1.07x0.57x0.35x
Asset Growth %-27.32%81.61%105.9%7.98%47.22%-23.08%-22.08%-70.61%-38.52%-87.15%
Total Current Liabilities13.29M44.86M78.51M69.87M143.55M127.89M111.71M47.73M45.8M50.13M
Accounts Payable2.58M16K3.35M6.67M12.55M9.76M22.42M15.26M15.48M15.56M
Days Payables Outstanding14.350.0910.6616.6925.36-675.8---
Short-Term Debt0000000000
Deferred Revenue (Current)4.14M28.34M47.56M38.71M96.64M85.71M51.78M07.56M30.22M
Other Current Liabilities3.38M5.9M9.69M13.61M20.74M20.84M11.88M11.73M14.57M9.87M
Current Ratio11.25x5.54x5.23x5.80x4.60x3.12x2.69x1.98x1.13x1.13x
Quick Ratio11.27x5.57x5.23x5.80x4.60x3.12x2.69x1.98x1.13x1.13x
Cash Conversion Cycle---------53.59
Total Non-Current Liabilities8.4M53.98M144.63M134.91M297.64M218.69M155.84M34.7M33.06M32.27M
Long-Term Debt0000000000
Capital Lease Obligations3.94M24.74M27.69M41.19M38.4M44.05M38.99M33.52M26.25M100.01M
Deferred Tax Liabilities-3.94M-24.74M6.71M6.57M7.18M6.64M6.27M0015K
Other Non-Current Liabilities001.96M5.71M7.01M1.22M1.21M1.19M933K3.81M
Total Liabilities21.7M98.84M223.88M204.78M441.18M346.58M267.55M82.43M78.86M82.4M
Total Debt3.94M24.74M27.69M44.41M42.09M48.08M43.11M38.1M30.57M25.42M
Net Debt-18.12M-25.09M-112.73M-36.02M-89.24M-130.79M-57.34M-7.1M-11.35M-5.1M
Debt / Equity0.03x0.13x0.08x0.10x0.08x0.13x0.15x0.46x1.34x1.34x
Debt / EBITDA----------0.25x
Net Debt / EBITDA---------0.05x
Interest Coverage----------
Total Equity
136.19M▲ 0%
187.9M▲ 38.0%
367.26M▲ 95.5%
432.74M▲ 17.8%
497.37M▲ 14.9%
375.34M▼ 24.5%
294.96M▼ 21.4%
82.89M▼ 71.9%
22.77M▼ 72.5%
6.24M▲ 0%
Equity Growth %-29.23%37.96%95.45%17.83%14.93%-24.53%-21.42%-71.9%-72.53%-265.18%
Book Value per Share1.932.413.793.863.702.601.910.480.110.02
Total Shareholders' Equity136.19M187.9M366.52M432.55M498.23M375.34M294.96M82.89M22.77M6.24M
Common Stock709K856K1.02M1.16M1.42M1.46M1.67M1.78M2.13M3.22M
Retained Earnings-440.91M-495.48M-562.7M-656.99M-777.98M-956.27M-1.15B-1.41B-1.5B-1.59B
Treasury Stock0000000000
Accumulated OCI20K-286K-1.44M-2.45M5.42M-3.99M-8.4M-4.59M-7.53M-1.45M
Minority Interest00739K185K-868K00000

SGMO Cash Flow Statement

Sangamo Therapeutics, Inc. (SGMO) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations-65.88M11.18M37.15M-144.4M169.88M-233.25M-223.63M-224.84M-67.14M-67.14M
Operating CF Margin %-339.8%30.57%43.99%-140.98%143.73%-210.7%-200.92%-127.58%-116.16%-
Operating CF Growth %-95.38%116.97%232.34%-488.68%217.64%-237.31%4.13%-0.54%70.14%-170.26%
Net Income-71.66M-54.57M-68.89M-95.42M-121.12M-178.3M-192.28M-257.83M-97.94M-108.91M
Depreciation & Amortization997K1.5M2.36M9.61M13.37M17.64M20.56M22.19M9.36M7.85M
Stock-Based Compensation15.06M9.09M14.68M19.33M25.71M32.96M31.65M27.36M12.38M10.23M
Deferred Taxes-14K-661K-5.23M-5.13M02.77M0-6.33M0-18K
Other Non-Cash Items320K80K966K218K-666K-6.43M-1.24M153.8M4.55M-657K
Working Capital Changes-10.59M55.74M93.27M-73.01M252.59M-101.89M-82.32M-164.03M4.51M15.34M
Change in Receivables-2.14M1.63M-1.33M-32.24M31.68M-789K2.33M-976K953K10.13M
Change in Inventory-1.03M-685K-1M4.19M-10.7M7.66M0000
Change in Payables-2.33M3.22M-6.37M-4.19M10.7M-7.66M13.35M5.59M-14.17M-3.02M
Cash from Investing18.13M-80.9M-178.11M-59.8M-271.63M248.2M59.28M153.53M37.52M1.24M
Capital Expenditures-732K-3.75M-43.06M-20.68M-14.71M-23.28M-20.17M-21.16M-267K-240K
CapEx % of Revenue3.78%10.26%50.99%20.18%12.45%21.03%18.12%12%0.46%-
Acquisitions00-75.65M-262K-704K-119K-79.46M01.95M0
Investments----------
Other Investing18.86M-3.5M-59.39M00079.46M001.48M
Cash from Financing337K97.49M231.71M142.03M153.1M32.86M84.66M14.59M28.38M62.94M
Debt Issued (Net)0000000000
Equity Issued (Net)1.11M81.57M215.76M136.31M142.53M27.1M84.87M15.11M28.99M65.93M
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing-776K15.92M15.95M5.72M10.57M5.76M-209K-518K-614K-2.99M
Net Change in Cash
-47.42M▲ 0%
27.77M▲ 158.6%
90.59M▲ 226.3%
-61.99M▼ 168.4%
50.9M▲ 182.1%
47.54M▼ 6.6%
-78.43M▼ 265.0%
-55.24M▲ 29.6%
-3.29M▲ 94.1%
-8.67M▲ 0%
Free Cash Flow
-66.61M▲ 0%
7.43M▲ 111.2%
-5.91M▼ 179.6%
-165.08M▼ 2691.8%
155.16M▲ 194.0%
-256.53M▼ 265.3%
-243.8M▲ 5.0%
-246M▼ 0.9%
-67.41M▲ 72.6%
-76.4M▲ 0%
FCF Margin %-343.57%20.31%-7%-161.16%131.28%-231.73%-219.05%-139.59%-116.62%-232.38%
FCF Growth %-84.37%111.15%-179.6%-2691.76%193.99%-265.33%4.96%-0.9%72.6%34.77%
FCF per Share-0.940.10-0.06-1.471.15-1.77-1.58-1.41-0.33-0.33
FCF Conversion (FCF/Net Income)0.92x-0.20x-0.54x1.52x-1.40x1.31x1.16x0.87x0.69x0.70x
Interest Paid0000000000
Taxes Paid0000000000

SGMO Key Ratios

Sangamo Therapeutics, Inc. (SGMO) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)-43.61%-33.67%-24.62%-23.8%-26.02%-40.86%-57.37%-136.47%-185.39%-813.95%
Return on Invested Capital (ROIC)-45.15%-30.1%-27.73%-24.23%-24.14%-42.14%-62.62%-131.14%-178.84%-178.84%
Gross Margin-238.43%-79.75%-36.01%-42.46%-52.84%100%89.12%100%100%100%
Net Margin-369.58%-149.23%-80.91%-92.93%-102.37%-161.05%-172.76%-146.3%-169.45%-331.28%
Debt / Equity0.03x0.13x0.08x0.10x0.08x0.13x0.15x0.46x1.34x1.34x
FCF Conversion0.92x-0.20x-0.54x1.52x-1.40x1.31x1.16x0.87x0.69x0.70x
Revenue Growth-50.96%88.6%130.95%21.29%15.39%-6.34%0.54%58.34%-67.2%-37.13%

SGMO Frequently Asked Questions

Sangamo Therapeutics, Inc. (SGMO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Sangamo Therapeutics, Inc. (SGMO) reported $32.9M in revenue for fiscal year 2024. This represents a 1394% increase from $2.2M in 1999.

Sangamo Therapeutics, Inc. (SGMO) saw revenue decline by 67.2% over the past year.

Sangamo Therapeutics, Inc. (SGMO) reported a net loss of $108.9M for fiscal year 2024.

Dividend & Returns

Sangamo Therapeutics, Inc. (SGMO) has a return on equity (ROE) of -185.4%. Negative ROE indicates the company is unprofitable.

Sangamo Therapeutics, Inc. (SGMO) had negative free cash flow of $76.4M in fiscal year 2024, likely due to heavy capital investments.

Explore More SGMO

Sangamo Therapeutics, Inc. (SGMO) financial analysis — history, returns, DCA and operating performance tools

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