Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in SLN held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | TCG Crossover Management, LLC | 3.0M | $16.0M | 0.0% | 6.422% | 0.46% |
| 2 | Siren, L.L.C. | 2.9M | $15.3M | 0.0% | 6.164% | 0.43% |
| 3 | Redmile Group, LLC | 2.2M | $11.4M | 0.0% | 4.583% | 0.76% |
| 4 | Nantahala Capital Management, LLC | 2.1M | $11.3M | +39.2% | 4.545% | 0.58% |
| 5 | CITADEL ADVISORS LLC | 1.2M | $6.6M | +381.4% | 2.638% | 0.00% |
| 6 | MILLENNIUM MANAGEMENT LLC | 1.1M | $5.7M | +62.9% | 2.274% | 0.00% |
| 7 | GREAT POINT PARTNERS LLC | 1.0M | $5.4M | +26.3% | 2.160% | 1.32% |
| 8 | Nextech Invest, Ltd. | 952K | $5.0M | 0.0% | 2.016% | 0.35% |
| 9 | Polygon Management Ltd. | 630K | $3.3M | +72.5% | 1.334% | 0.64% |
| 10 | 5AM Venture Management, LLC | 476K | $2.5M | 0.0% | 1.008% | 0.70% |
| 11 | Ikarian Capital, LLC | 866K | $1.7M | 0.0% | 1.833% | 0.18% |
| 12 | Jones Hill Capital LP | 302K | $1.6M | β | 0.638% | 0.34% |
| 13 | UBS Group AG | 247K | $1.3M | +19.0% | 0.523% | 0.00% |
| 14 | BOOTHBAY FUND MANAGEMENT, LLC | 209K | $1.1M | 0.0% | 0.443% | 0.03% |
| 15 | BlackRock, Inc. | 205K | $1.1M | +179.9% | 0.434% | 0.00% |
| 16 | BANK OF MONTREAL /CAN/ | 203K | $1.1M | +26.4% | 0.430% | 0.00% |
| 17 | ADAR1 Capital Management, LLC | 172K | $907K | +628.1% | 0.364% | 0.06% |
| 18 | MARSHALL WACE, LLP | 170K | $894K | +8.9% | 0.359% | 0.00% |
| 19 | Seven Fleet Capital Management LP | 157K | $826K | +6.2% | 0.332% | 0.26% |
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 154K | $814K | +268.8% | 0.327% | 0.00% |
| 21 | BNP PARIBAS ARBITRAGE, SA | 148K | $778K | +1127.8% | 0.313% | 0.00% |
| 22 | Ishara Investments LP | 141K | $740K | -41.5% | 0.298% | 0.70% |
| 23 | HSBC HOLDINGS PLC | 123K | $640K | β | 0.260% | 0.00% |
| 24 | Point72 Asset Management, L.P. | 120K | $631K | +5.0% | 0.253% | 0.00% |
| 25 | XTX Topco Ltd | 106K | $559K | +804.6% | 0.224% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in SLN β a direct measure of their conviction.
Filings activity in SLN during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new SLN position in Q1 2026
Institutions that fully closed their SLN position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 55 | 3.5% | 31.87% | 0.94 pp | $101M | 2.9% |
| Q4 2025 | 57 | +5.6% | 32.81% | +2.84 pp | $104M | +9.5% |
| Q3 2025 | 54 | 5.3% | 29.97% | 3.65 pp | $95M | 11% |
| Q2 2025 | 57 | 3.4% | 33.62% | +14.79 pp | $106M | +79% |
| Q1 2025 | 59 | 11% | 18.83% | 33.51 pp | $60M | 64% |
| Q4 2024 | 66 | 2.9% | 52.34% | 93.15 pp | $165M | 64% |
| Q3 2024 | 68 | 2.9% | 145.49% | 8.06 pp | $460M | 5.2% |
| Q2 2024 | 70 | β | 153.55% | β | $485M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying SLN stock.
Based on Q1 2026 13F filings, institutional ownership of Silence Therapeutics plc stands at 31.9%, held across 55 reporting institutions.
TCG Crossover Management, LLC is the largest reported institutional holder of SLN, with approximately 3,033,560 shares worth $0.02B as of Q1 2026.
Yes β 4 widely-followed marquee investors appear among the top 25 institutional holders of SLN, including CITADEL ADVISORS LLC, MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, Point72 Asset Management, L.P..
Our composite Smart Money Score for SLN is 50 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
7 institutions opened new positions in SLN during Q1 2026, while 9 fully exited. 16 added to existing positions and 30 trimmed.
SLN institutional ownership fell by 0.94 percentage points quarter-over-quarter, with a net change of -2 holders.
The top 10 institutions account for 81.9% of all reported 13F value in SLN, and the top 25 account for 96.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Silence Therapeutics plc (SLN) Institutional Ownership