Silexion Therapeutics Ltd. (SLXN) P/E Ratio History
Deep ValueTrading at -0.0x · 0th percentile of 5-year range · Significant discount to historical valuation · Data 2025–2026
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P/E Ratio Analysis
As of June 23, 2026, Silexion Therapeutics Ltd. (SLXN) trades at a price-to-earnings ratio of -0.0x, with a stock price of $2.70 and trailing twelve-month earnings per share of $-39.96.
The current P/E is 102% below its 5-year average of 1.4x. Over the past five years, SLXN's P/E has ranged from a low of 0.3x to a high of 4.5x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 22.1x, SLXN trades at a 100% discount to its sector peers. The sector includes 233 companies with P/E ratios ranging from 0.0x to 194.5x.
Relative to the broader market, SLXN trades at a notable discount to the S&P 500 median P/E of 24.3x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our SLXN DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
SLXN Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
SLXN P/E vs Peers
RNA and Genome Editing Developers peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $64B | 14.8Lowest | 2.32Best | +8% | |
| $25B | 29.6 | 7.02 | +171%Best | |
| $172B | 26.2 | 12.40 | +7% |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
SLXN Historical P/E Data (2025–2026)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Period End | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2026 Q1 | - | $12.80 | $49.40 | 0.3x | -81% |
| FY2025 Q4 | Dec 31 2025 | $19.20 | $55.30 | 0.3x | -75% |
| FY2025 Q3 | - | $34.00 | $67.50 | 0.5x | -64% |
| FY2025 Q2 | Jun 30 2025 | $121.50 | $27.20 | 4.5x | +220% |
Average P/E for displayed period: 1.4x
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
1+ years return with dividends reinvested.
DCA Calculator
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Peer Comparison
Compare growth, multiples, and margins vs sector.
SLXN — Frequently Asked Questions
Quick answers to the most common questions about buying SLXN stock.
What is SLXN's P/E ratio?
Silexion Therapeutics Ltd. (SLXN) trailing twelve-month P/E ratio is -0.0x, based on TTM diluted EPS of $-39.96. The 5-year average P/E is 1.4x and the historical range spans 0.3x to 4.5x.
Is SLXN stock overvalued or undervalued?
SLXN current P/E: -0.0x. 5-year average P/E: 1.4x. Percentile: 0th.
Is SLXN stock expensive?
SLXN is fairly valued relative to its own history. The current P/E of -0.0x is near the 5-year average of 1.4x (0th percentile of historical range).
What is SLXN's historical P/E range?
Over the past 5 years, SLXN's P/E ratio has ranged from 0.3x to 4.5x, with a median of 0.5x and an average of 1.4x. The current P/E of -0.0x places the stock at the 0th percentile of this range. Full historical data spans 2025–2026.
How does SLXN's P/E compare to the S&P 500?
SLXN current P/E: -0.0x. S&P 500 median P/E: 24.3x.
How does SLXN's valuation compare to Healthcare peers?
Silexion Therapeutics Ltd. P/E of -0.0x can be benchmarked against Healthcare peers in the comparison table on this page.
What is SLXN's PEG ratio?
SLXN PEG ratio is N/A, based on a P/E of -0.0x and EPS growth of -239.4%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is SLXN's earnings yield?
SLXN earnings yield is N/A, the inverse of its -0.0x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.