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SLXNSilexion Therapeutics Ltd.
$0.15$99804
Overview & Tools
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SLXN logo

Silexion Therapeutics Ltd.

SLXN
NASDAQ · Cell & Gene Therapy
$0.15
At close - Nov 6, 4:00 PM EST - USD
Market Cap$99804
P/E-0.0x
52W High$32.40
Volume192.82K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Clinical Development Costs Threaten Capital Liquidity Sustainability

Silexion Therapeutics faces a precarious financial outlook as it attempts to advance its LODER platform without a commercial revenue stream to offset significant R&D expenditures.

GrowthContracting
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

SLXN price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/11 Beats

EPS beat 5 of last 11 quarters

02

Valuation risk

-100% Peers

P/E is 100% below peer median

03

Market leadership

RS 2 · Lag

Laggard (Underperforming 98% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystConfirmed earnings · Nov 11

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
SLXN-99.23%
S&P 500 (^GSPC)+7.63%
1-Year Return
SLXN-99.49%
S&P 500 (^GSPC)+9.69%
3-Year Return
SLXN-99.99%
S&P 500 (^GSPC)+68.76%
5-Year Return
SLXN-99.99%
S&P 500 (^GSPC)+56.80%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$12M+27.6% YoY
Free cash flow FY25
-$11M-28.6% YoY
Operating margin FY25
-
ROIC (FY25)-
Avg ROIC 5Y-3.5%
ROE (TTM)-563.1%
Piotroski Score4 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/11 (56%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 14, 2026
-$5.17+75.6%
vs -$21.20
—
vs —
Q2 2026
May 15, 2026
-$0.85+34.1%
vs -$1.29
—
vs —
Q2 2026
May 12, 2026
-$8.50+34.1%
vs -$12.90
—
vs —
Q2 2026
Mar 17, 2026
-$23.85-1938.5%
vs -$1.17
—
vs —
Historical baseline: 11 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
GlobeNewsWire·Sep 30, 2026
Silexion Therapeutics Announces First Patient Successfully Dosed in Phase 2/3 Clinical Trial of SIL204 in Locally Advanced Pancreatic Cancer

Global Phase 2/3 trial evaluates SIL204 in combination with standard chemotherapy in patients with locally advanced pancreatic cancer

GlobeNewsWire·Sep 29, 2026
Silexion Therapeutics Announces Exercise of Warrants

Cayman Islands, Sept. 29, 2026 (GLOBE NEWSWIRE) -- Silexion Therapeutics Corp. (NASDAQ: SLXN) (“Silexion” or the “Company”), a clinical-stage biotechnology company pioneering RNA interference (RNAi) therapies for KRAS-driven cancers, today announced the entry into definitive agreements for the immediate exercise of certain outstanding series E warrants to purchase up to an aggregate of 3,216,928 of the Company's ordinary shares originally issued in August 2026 having a reduced exercise price of $0.2603 per share. The ordinary shares issuable upon exercise of the warrants are registered pursuant to an effective registration statement on Form S-1 (File No. 333-298137). The gross proceeds to the Company from the exercise of the warrants are expected to be $837,366.36, prior to deducting placement agent fees and estimated offering expenses. The offering is expected to close on or about September 29, 2026, subject to satisfaction of customary closing conditions. The Company intends to use the net proceeds from the offering as working capital for general corporate purposes.

GlobeNewsWire·Sep 28, 2026
Silexion Therapeutics Reports Positive Preclinical Findings for SIL204, Demonstrating Key Mechanism for Endogenous Systemic Uptake in KRAS-Driven Cancers

Translational research demonstrates that SIL204 utilizes native serum lipids to facilitate intracellular delivery and robust KRAS oncogene knockdown

GlobeNewsWire·Sep 9, 2026
Silexion Therapeutics to Participate in September 2026 Industry and Investor Conferences

Grand Cayman, Cayman Islands, Sept. 09, 2026 (GLOBE NEWSWIRE) -- Silexion Therapeutics Corp. (NASDAQ: SLXN) (“Silexion” or the “Company”), a clinical-stage biotechnology company pioneering RNA interference (RNAi) therapies for KRAS-driven cancers, today announced that members of its management team will participate in the following industry and investor conferences in September 2026: Oncology & Immunology Innovation Partnering & Licensing Summit Presentation date: September 9, 2026 Location: Hotel Commonwealth, Boston, MA Format: Presentation Presenter: Dr. Mitchell Shirvan, Chief Scientific and Development Officer 8th Annual RAS-Targeted Drug Development Summit Presentation date: September 10, 2026 Location: The Colonnade Hotel, Boston, MA Format: Presentation Presenter: Dr. Mitchell Shirvan, Chief Scientific and Development Officer H.C.

Filtered for Silexion Therapeutics Ltd.More Headlines
04

Compare before deciding

Benchmark SLXN against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Silexion Therapeutics Ltd. (SLXN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SLXN logoSLXNSilexion Therapeutics Ltd.Current
$0.15$99.8K-0.01——-563.11%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$17.82$1.88B127.9315.58%0.75%1.04%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$58.16$8.19B-26.0623258.15%-47.79%-60.05%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$11.35$1.27B-3.7316.92%-805.75%-64.73%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$39.42$6.55B-11.5533.87%-64.64%-110.84%—
REGN logoREGNRegeneron Pharmaceuticals, Inc.
$904.35$93.17B19.820.99%28.51%15.07%0.38%

Compare SLXN vs Peers

Silexion Therapeutics Ltd. (SLXN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for SLXN.

Scale Benchmark

vs TMO

Larger-name benchmark to compare SLXN against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, ARWR, NTLA, IONS

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

SLXN SEC Filings & Documents

Silexion Therapeutics Ltd. (SLXN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 21, 2026·SEC

Material company update

Aug 14, 2026·SEC

Material company update

Aug 13, 2026·SEC

10-K Annual Reports

1
FY 2026

Mar 17, 2026·SEC

10-Q Quarterly Reports

4
FY 2026

Aug 14, 2026·SEC

FY 2026

May 15, 2026·SEC

FY 2025

Nov 12, 2025·SEC

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SLXN Frequently Asked Questions

Silexion Therapeutics Ltd. (SLXN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is SLXN profitable?

No. Silexion Therapeutics Ltd. (SLXN) reported a net loss of $14.0M over the trailing twelve months.

Dividend & Returns
What is SLXN's return on equity?

Silexion Therapeutics Ltd. (SLXN) had a return on equity (ROE) of -563.1% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Silexion Therapeutics Ltd.'s free cash flow?

Silexion Therapeutics Ltd. (SLXN) had negative free cash flow of $12.4M over the trailing twelve months.

What if you invested $1,000 in SLXN back in 2020?

Total return calculator · dividends reinvested · 6+ years of data

See returns →