Spruce Biosciences, Inc. (SPRB) Stock Price History
Historical prices from 2020 to 2026
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SPRB Historical Performance
Short-Term Returns
SPRB Stock Price Trajectory (2020–2026)
As of May 8, 2026, Spruce Biosciences, Inc. (SPRB) trades at $56.57, representing a +932.3% return over the past year. The stock has delivered a -95.1% total return over five years (-45.3% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $2,670.00 on November 27, 2020. From this peak, SPRB has corrected -97.9%, currently trading 14% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers CORT (-27.5% 1Y), XNCR (+54.1% 1Y), and NTLA (+88.1% 1Y), SPRB has outperformed the peer group average. Compare SPRB vs CORT →
SPRB Historical Price Data (2025–2026)
Showing 30 of 1,401 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-07 | 56.90 | 57.39 | 55.55 | 56.57 | 21K | -2.25% |
| 2026-05-06 | 58.49 | 60.27 | 57.26 | 57.87 | 44K | -2.48% |
| 2026-05-05 | 59.05 | 60.08 | 58.55 | 59.34 | 32K | -0.05% |
| 2026-05-04 | 57.73 | 59.84 | 57.70 | 59.37 | 45K | +3.65% |
| 2026-05-01 | 57.23 | 57.39 | 55.88 | 57.28 | 30K | -0.07% |
| 2026-04-30 | 57.21 | 58.13 | 54.90 | 57.32 | 31K | +3.24% |
| 2026-04-29 | 55.84 | 57.36 | 54.33 | 55.52 | 47K | +1.37% |
| 2026-04-28 | 56.88 | 57.00 | 54.05 | 54.77 | 83K | -4.21% |
| 2026-04-27 | 56.09 | 58.29 | 55.38 | 57.18 | 107K | +5.17% |
| 2026-04-24 | 53.64 | 55.90 | 53.64 | 54.37 | 58K | +0.67% |
| 2026-04-23 | 53.61 | 55.89 | 52.31 | 54.01 | 92K | +3.15% |
| 2026-04-22 | 56.75 | 56.75 | 52.01 | 52.36 | 185K | +1.30% |
| 2026-04-21 | 58.00 | 58.69 | 51.56 | 51.69 | 644K | -24.25% |
| 2026-04-20 | 69.84 | 70.67 | 67.67 | 68.24 | 11K | -2.93% |
| 2026-04-17 | 70.45 | 74.00 | 67.63 | 70.30 | 32K | +4.93% |
| 2026-04-16 | 68.10 | 70.22 | 66.66 | 67.00 | 18K | -4.82% |
| 2026-04-15 | 70.00 | 71.46 | 66.82 | 70.39 | 51K | +3.82% |
| 2026-04-14 | 65.00 | 68.85 | 59.25 | 67.80 | 101K | +5.10% |
| 2026-04-13 | 61.98 | 68.48 | 61.98 | 64.51 | 62K | +1.38% |
| 2026-04-10 | 64.47 | 66.32 | 63.32 | 63.63 | 82K | -3.61% |
| 2026-04-09 | 64.70 | 67.96 | 63.50 | 66.01 | 84K | +3.71% |
| 2026-04-08 | 63.52 | 66.80 | 62.00 | 63.65 | 139K | +2.41% |
| 2026-04-07 | 63.65 | 64.49 | 58.39 | 62.15 | 61K | -1.36% |
| 2026-04-06 | 72.00 | 72.00 | 62.72 | 63.01 | 49K | -10.62% |
| 2026-04-02 | 69.36 | 71.76 | 67.50 | 70.50 | 37K | +1.39% |
| 2026-04-01 | 64.50 | 69.53 | 64.28 | 69.53 | 51K | +6.40% |
| 2026-03-31 | 58.61 | 65.35 | 58.61 | 65.35 | 22K | +11.65% |
| 2026-03-30 | 64.43 | 64.43 | 55.98 | 58.53 | 34K | -7.15% |
| 2026-03-27 | 69.00 | 70.25 | 61.39 | 63.04 | 38K | -8.78% |
| 2026-03-26 | 69.29 | 74.83 | 67.64 | 69.11 | 41K | -1.23% |
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View ValuationCompare SPRB vs DBVT
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Start ComparisonSPRB — Frequently Asked Questions
Quick answers to the most common questions about buying SPRB stock.
How has SPRB stock performed recently?
SPRB returned +932.3% over the past year, beating its 5-year annualized CAGR of -45.3%. The stock trades below its 200-day moving average, confirming the uptrend.
What is SPRB's all-time high price?
Spruce Biosciences, Inc. reached $2670.00 on 2020-11-27. The 52-week high is $240.00. Current 1-year return of +932.3% places the stock closer to historical peaks.
Where can I download SPRB historical price data?
This page provides SPRB daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2020-2026, downloadable in CSV format.