Spruce Biosciences, Inc. (SPRB) Stock Price History
Historical prices from 2020 to 2026
- 1M
- +6.4%
- 3M
- -20.3%
- YTD
- -39.2%
- 1Y
- +949.7%
- 3Y
- -30.8%
- 5Y
- -41.9%
Loading 10-year price history...
SPRB Historical Performance
SPRB Annual Returns
Year-by-year price performance · 2020–2026
- 2020 annual price return
- +43.0%
- 2021 annual price return
- -80.4%
- 2022 annual price return
- -76.1%
- 2023 annual price return
- +154.8%
- 2024 annual price return
- -85.8%
- 2025 annual price return
- +177.2%
- 2026 annual price return
- -39.4%
SPRB Stock Price Trajectory (2020–2026)
As of June 29, 2026, Spruce Biosciences, Inc. (SPRB) trades at $55.11, representing a +949.7% return over the past year. The stock has delivered a -93.5% total return over five years (-41.9% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $2,670.00 on November 27, 2020. From this peak, SPRB has corrected -97.9%, currently trading 24% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers CORT (+17.5% 1Y), XNCR (+79.2% 1Y), and NTLA (+73.6% 1Y), SPRB has outperformed the peer group average. Compare SPRB vs CORT →
SPRB Historical Price Data · from 2020
Rows 1–50 of 1,435| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-26 | 51.78 | 55.22 | 51.78 | 55.11 | 0 | +4.43% |
| 2026-06-25 | 52.66 | 53.62 | 50.11 | 52.77 | 56K | +1.74% |
| 2026-06-24 | 52.50 | 52.51 | 50.39 | 51.87 | 31K | -0.52% |
| 2026-06-23 | 53.49 | 55.10 | 52.10 | 52.14 | 53K | -3.80% |
| 2026-06-22 | 52.05 | 55.95 | 52.00 | 54.20 | 92K | +3.51% |
| 2026-06-18 | 50.49 | 52.90 | 49.69 | 52.36 | 139K | +7.38% |
| 2026-06-17 | 47.72 | 51.47 | 46.49 | 48.76 | 72K | +1.37% |
| 2026-06-16 | 50.92 | 51.52 | 47.13 | 48.10 | 59K | -3.62% |
| 2026-06-15 | 50.90 | 52.13 | 48.61 | 49.91 | 9K | -3.83% |
| 2026-06-12 | 49.91 | 53.25 | 49.02 | 51.89 | 62K | +5.67% |
| 2026-06-11 | 46.87 | 49.88 | 46.50 | 49.10 | 68K | +4.19% |
| 2026-06-10 | 49.77 | 50.38 | 47.13 | 47.13 | 34K | -3.88% |
| 2026-06-09 | 50.72 | 52.18 | 46.70 | 49.03 | 42K | -0.59% |
| 2026-06-08 | 50.40 | 51.10 | 48.66 | 49.32 | 31K | -2.20% |
| 2026-06-05 | 53.22 | 53.22 | 49.50 | 50.43 | 34K | -5.15% |
| 2026-06-04 | 50.02 | 54.32 | 50.02 | 53.17 | 67K | +8.40% |
| 2026-06-03 | 48.09 | 50.50 | 48.00 | 49.05 | 65K | -0.51% |
| 2026-06-02 | 50.34 | 50.70 | 48.58 | 49.30 | 31K | -2.76% |
| 2026-06-01 | 50.01 | 53.08 | 50.00 | 50.70 | 31K | -1.11% |
| 2026-05-29 | 50.04 | 52.05 | 47.81 | 51.27 | 54K | +5.65% |
| 2026-05-28 | 50.33 | 51.51 | 48.00 | 48.53 | 49K | -2.00% |
| 2026-05-27 | 52.11 | 52.11 | 49.52 | 49.52 | 29K | -4.42% |
| 2026-05-26 | 52.42 | 54.05 | 51.10 | 51.81 | 50K | +1.44% |
| 2026-05-22 | 52.04 | 55.32 | 50.40 | 51.08 | 0 | -3.08% |
| 2026-05-21 | 50.18 | 53.00 | 49.55 | 52.70 | 51K | +2.30% |
| 2026-05-20 | 49.89 | 52.60 | 49.00 | 51.52 | 60K | +6.77% |
| 2026-05-19 | 50.85 | 51.61 | 48.25 | 48.25 | 89K | -6.15% |
| 2026-05-18 | 52.60 | 54.20 | 50.40 | 51.41 | 73K | -4.41% |
| 2026-05-15 | 57.92 | 57.92 | 53.30 | 53.78 | 49K | -8.85% |
| 2026-05-14 | 57.25 | 59.00 | 56.65 | 59.00 | 29K | +2.52% |
| 2026-05-13 | 56.13 | 59.20 | 55.91 | 57.55 | 49K | +1.56% |
| 2026-05-12 | 57.10 | 57.70 | 53.81 | 56.66 | 36K | +0.47% |
| 2026-05-11 | 57.53 | 58.10 | 56.11 | 56.40 | 45K | -0.18% |
| 2026-05-08 | 57.55 | 57.55 | 56.30 | 56.50 | 25K | -0.12% |
| 2026-05-07 | 56.90 | 57.39 | 55.55 | 56.57 | 21K | -2.25% |
| 2026-05-06 | 58.49 | 60.27 | 57.26 | 57.87 | 44K | -2.48% |
| 2026-05-05 | 59.05 | 60.08 | 58.55 | 59.34 | 32K | -0.05% |
| 2026-05-04 | 57.73 | 59.84 | 57.70 | 59.37 | 45K | +3.65% |
| 2026-05-01 | 57.23 | 57.39 | 55.88 | 57.28 | 30K | -0.07% |
| 2026-04-30 | 57.21 | 58.13 | 54.90 | 57.32 | 31K | +3.24% |
| 2026-04-29 | 55.84 | 57.36 | 54.33 | 55.52 | 47K | +1.37% |
| 2026-04-28 | 56.88 | 57.00 | 54.05 | 54.77 | 83K | -4.21% |
| 2026-04-27 | 56.09 | 58.29 | 55.38 | 57.18 | 107K | +5.17% |
| 2026-04-24 | 53.64 | 55.90 | 53.64 | 54.37 | 58K | +0.67% |
| 2026-04-23 | 53.61 | 55.89 | 52.31 | 54.01 | 92K | +3.15% |
| 2026-04-22 | 56.75 | 56.75 | 52.01 | 52.36 | 185K | +1.30% |
| 2026-04-21 | 58.00 | 58.69 | 51.56 | 51.69 | 644K | -24.25% |
| 2026-04-20 | 69.84 | 70.67 | 67.67 | 68.24 | 11K | -2.93% |
| 2026-04-17 | 70.45 | 74.00 | 67.63 | 70.30 | 32K | +4.93% |
| 2026-04-16 | 68.10 | 70.22 | 66.66 | 67.00 | 18K | -4.82% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
SPRB — Frequently Asked Questions
Quick answers to the most common questions about buying SPRB stock.
How has SPRB stock performed recently?
SPRB returned +949.7% over the past year, beating its 5-year annualized CAGR of -41.9%. The stock trades below its 200-day moving average, confirming the uptrend.
What is SPRB's all-time high price?
Spruce Biosciences, Inc. reached $2670.00 on 2020-11-27. The 52-week high is $240.00. Current 1-year return of +949.7% places the stock closer to historical peaks.
Where can I download SPRB historical price data?
This page provides SPRB daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2020-2026, downloadable in CSV format.