Spruce Biosciences, Inc. (SPRB) Revenue History
Annual and quarterly revenue from 2018 to present
SPRB Revenue Over Time (2018–2025)
SPRB Revenue Growth History
0 of 2 years with positive growth- FY2018 revenue growth
- N/A
- FY2019 revenue growth
- N/A
- FY2020 revenue growth
- N/A
- FY2021 revenue growth
- N/A
- FY2022 revenue growth
- N/A
- FY2023 revenue growth
- N/A
- FY2024 revenue growth
- -51.3%
- FY2025 revenue growth
- -100.0%
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $0 | — |
| Q4 2025 | $0 | -100.0% |
| Q3 2025 | $0 | -100.0% |
| Q2 2025 | $0 | -100.0% |
| Q1 2025 | $0 | -100.0% |
| Q4 2024 | $697K | -75.9% |
| Q3 2024 | $602K | -80.4% |
| Q2 2024 | $1.6M | -25.6% |
Multi-year avg. share of annual revenue by fiscal quarter
SPRB Revenue Analysis (2018–2025)
Current Revenue & Growth
As of June 28, 2026, Spruce Biosciences, Inc. (SPRB) generated trailing twelve-month (TTM) revenue of $0. The most recent quarter (Q1 2026) recorded $0 in revenue
Historical Growth Trajectory
SPRB's historical revenue data shows various trends over time. Spruce Biosciences, Inc.'s highest annual revenue of $10.1 million was recorded in 2023.
Peer Comparison
Compared to Healthcare sector peers — including CORT (+12.2% YoY), XNCR (-32.5% YoY), and NTLA (+45.0% YoY). Compare SPRB vs CORT →
SPRB Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| SPRBCurrent | $0 | - | - | - | |
 CORT | $761M | +12.2% | +16.6% | 5.9% | |
 XNCR | $126M | -32.5% | +0.5% | -141.4% | |
 NTLA | $68M | +45.0% | +3.1% | -651.7% | |
 RARE | $673M | +13.3% | +19.9% | -79.5% | |
 ACRS | $8M | -52.9% | +3.8% | -975.9% |
SPRB Historical Revenue Data (2018–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $0 | -100.0% | $0 | - | $-36,513,000 | - |
| 2024 | $4.9M | -51.3% | $4.9M | 100.0% | $-56,151,000 | -1143.4% |
| 2023 | $10.1M | - | $10.1M | 100.0% | $-51,993,000 | -515.3% |
| 2022 | $0 | - | $0 | - | $-47,283,000 | - |
| 2021 | $0 | - | $0 | - | $-42,066,000 | - |
| 2020 | $0 | - | $0 | - | $-29,416,000 | - |
| 2019 | $0 | - | $-12,000 | - | $-13,107,000 | - |
| 2018 | $0 | - | $-1,000 | - | $-9,972,000 | - |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
8+ years return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
SPRB — Frequently Asked Questions
Quick answers to the most common questions about buying SPRB stock.
Is SPRB's revenue growth accelerating or slowing?
SPRB TTM revenue: $0.00. YoY growth: N/A. 5-year CAGR: N/A.
What is SPRB's revenue history from 2018 to 2026?
Spruce Biosciences, Inc. (SPRB) revenue history spans 2018 to 2026. TTM revenue as of 2026 is $0.00, growing at N/A YoY. The 5-year CAGR is N/A. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is SPRB's long-term revenue growth rate (CAGR)?
Spruce Biosciences, Inc.'s 5-year revenue CAGR of N/A reflects the variable nature of its business expansion. As of 2026, the current YoY growth rate of N/A is in line with this long-term average. CAGR is the most reliable measure of sustained revenue momentum for SPRB.
Why does SPRB's quarterly revenue fluctuate?
SPRB quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. Spruce Biosciences, Inc.'s revenue data from 2018 to 2026 shows full historical quarterly detail on this page.
How is SPRB's revenue distributed by segment?
SPRB reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does SPRB's revenue compare to industry peers?
Spruce Biosciences, Inc. (SPRB) with TTM revenue of $0.00 and N/A YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.