Free cash flow has averaged approximately -$12.8 million per quarter over the last four periods, reflecting an operational cash drain that is only partially offset by stock-based compensation.
Shattuck Labs, Inc. (STTK) cash flow statement — 8-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 |
|---|
| Cash from Operations | -49.57M | -39.88M | -60.52M | -81.23M | -94.5M | -57.12M | -33.66M | -20.98M | -6.9M |
| Operating CF Margin % | - | -3988.2% | -1057.77% | -4902.11% | -14493.56% | -190.28% | -338.83% | -212.15% | -30.76% |
| Operating CF Growth % | -53.74% | 34.1% | 25.5% | 14.04% | -65.45% | -69.69% | -60.47% | -203.85% | - |
| Net Income | -67.72M | -48.81M | -75.41M | -87.3M | -101.94M | -44.97M | -36.6M | -23.98M | -7.39M |
| Depreciation & Amortization | 4.27M | 3.69M | 3.83M | 4.04M | 3.07M | 1.38M | 618K | 537K | 255K |
| Stock-Based Compensation | 10.05M | 7M | 9.55M | 6.94M | 6.46M | 5.47M | 1.27M | 461K | 425K |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 3.04M | 1K | 0 | -404K |
| Other Non-Cash Items | -370K | -971K | -1.5M | -816K | 2.38M | 1.52M | 89K | -207K | 2.71M |
| Working Capital Changes | 4.19M | -785K | 3.02M | -4.09M | -4.46M | -23.55M | 970K | 2.22M | -2.5M |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 2.76M | -318K | 832K | -5.63M | -2.84M | 7.87M | -1.75M | 1M | 1.12M |
| Cash from Investing | -89.37M | -7.89M | -8.51M | 110.86M | 49.44M | -10.44M | -146.32M | -3.59M | -29.93M |
| Capital Expenditures | -191K | -71K | -59K | -407K | -11.61M | -7.93M | -727K | -470K | -1.18M |
| CapEx % of Revenue | - | 7.1% | 1.03% | 24.56% | 1781.29% | 26.41% | 7.32% | 4.75% | 5.25% |
| Acquisitions | 0 | 0 | 0 | 0 | 104K | 2.52M | 145.59M | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | 0 | 0 | -2.52M | -145.59M | 0 | -15K |
| Cash from Financing | 158.15M | 44.57M | 787K | 48.62M | 171K | 1.93M | 330.87M | -64K | 35.15M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 158.43M | 44.64M | -17K | 48.67M | 171K | 1.93M | 349.92M | 0 | 35.3M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -284K | -65K | 804K | -53K | 0 | 0 | -19.05M | -64K | -152K |
| Net Change in Cash | 19.21M | -3.19M | -68.24M | 78.25M | -44.89M | -65.63M | 150.88M | -24.63M | -1.68M |
| Free Cash Flow | -49.76M | -39.95M | -60.57M | -81.64M | -106.11M | -65.04M | -34.39M | -21.45M | -8.08M |
| FCF Margin % | - | -3995.3% | -1058.8% | -4926.67% | -16274.85% | -216.68% | -346.14% | -216.9% | -36.01% |
| FCF Growth % | -1.9% | 34.04% | 25.8% | 23.07% | -63.14% | -89.15% | -60.35% | -165.38% | - |
| FCF per Share | -0.27 | -0.57 | -1.19 | -1.92 | -2.50 | -1.55 | -0.82 | -0.51 | -0.54 |
| FCF Conversion (FCF/Net Income) | 0.73x | 0.82x | 0.80x | 0.93x | 0.93x | 1.27x | 0.92x | 0.87x | 0.93x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying STTK stock.
Shattuck Labs, Inc. (STTK) generated $-39.9M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Shattuck Labs, Inc. (STTK) reported negative free cash flow of $40.0M in 2025, indicating capital requirements exceeded cash from operations.
Shattuck Labs, Inc. (STTK) spent $0.1M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Persistent cash burn with no revenue
Metrics are mathematically derived from official filings.
Consistent Cash Burn Trail Net Losses
Operating cash flow consistently trails net losses, with the OCF/NI ratio averaging 0.82 over the last four quarters, indicating that accruals are slightly reducing reported losses. According to the provided financials, this persistent shortfall suggests limited cash conversion from net income, which is negative.
The relationship between net income and operating cash flow is notably consistent, with OCF almost always being a slightly smaller negative number than net income. This indicates that non-cash expenses, primarily stock-based compensation and depreciation, are the main drivers of the difference, but they are not sufficient to create positive cash flow from operations. For a pre-revenue biotech, this pattern is expected, as net losses are driven by R&D and SG&A cash outlays, with the small gap confirming that accrual adjustments are minimal.
Negative FCF Reflects Unfunded Operations
Free cash flow has remained deeply negative, averaging approximately -$12.8 million per quarter over the last four periods, with the reported 2026Q3 FCF margin of -9.0% underscoring the operational cash drain. As reported in the financial data, this trend confirms the company is consuming capital at a steady pace.
The FCF trajectory shows no sign of inflection, with quarterly deficits persisting well above $10 million in most recent periods. This is a direct function of the company's operational structure, where R&D and SG&A spending are fixed cash outlays in the absence of meaningful revenue. The trajectory is deteriorating in the sense that the absolute cash burn remains substantial, and the lack of revenue means there is no natural offset to these expenditures, making the path to positive FCF entirely dependent on external funding or a partnership deal.
Minimal CapEx Highlights R&D Focus
Capital expenditures are negligible, with total CapEx over the last ten quarters summing to less than $0.4 million, indicating an asset-light model focused on intellectual property rather than physical infrastructure. Based on the company's reported figures, this minimizes cash outflows but underscores that all value creation is tied to unproven pipeline assets.
The near-zero CapEx profile is consistent with a clinical-stage biotechnology firm that outsources most manufacturing and does not maintain significant fixed assets. This lack of capital intensity means that virtually all operating cash flow is directed toward personnel and research activities. However, this also implies that the company's asset base is intangible and may not support traditional debt financing, increasing reliance on equity markets to fund operations.
No Deployment as Capital Preserves Runway
Capital deployment has been effectively zero, with no dividends or share repurchases and only a minor $17,000 acquisition in 2024Q2, indicating all available cash is directed toward funding core operations. As noted in the financial statements, this defensive posture is typical for a cash-burning entity with no revenue.
The absence of any shareholder returns or material M&A activity confirms that management is conserving cash to extend the operational runway. The single small acquisition appears to be an opportunistic, likely IP-related purchase, not a strategic transformation. This lack of deployment is a necessity, not a choice; any significant cash outflow for non-operational purposes would immediately heighten solvency concerns.
SBC is the Key Non-Cash Offset
Stock-based compensation, which averaged $2.1 million per quarter over the last four periods, is the primary non-cash adjustment inflating operating cash flow relative to net income. This warrants scrutiny, as it represents a recurring, non-cash expense that still dilutes shareholders, even though it does not consume cash.
While SBC does not impact the cash flow statement directly, it is a material cost of compensation that is excluded from net income but included as a non-cash add-back in the operating cash flow calculation. For investors, this means the reported operating cash flow, while still negative, is somewhat artificially supported by a non-cash charge. The persistent SBC suggests the company relies on equity-based compensation to attract talent, which is a standard practice but accelerates shareholder dilution in the absence of revenue growth.