Synlogic, Inc. (SYBX) Stock Price History
Historical prices from 2015 to 2026
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SYBX Historical Performance
Short-Term Returns
SYBX Stock Price Trajectory (2015–2026)
As of May 8, 2026, Synlogic, Inc. (SYBX) trades at $0.60, representing a -48.8% return over the past year. The stock has delivered a -98.7% total return over five years (-57.8% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $478.80 on May 3, 2016. From this peak, SYBX has corrected -99.9%, currently trading 49% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers IMVT (+102.4% 1Y), ACMR (+166.8% 1Y), and AGEN (+25.7% 1Y), SYBX has underperformed the peer group average. Compare SYBX vs IMVT →
SYBX Historical Price Data (2025–2026)
Showing 30 of 2,659 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-08 | 0.62 | 0.62 | 0.60 | 0.60 | 56 | +0.67% |
| 2026-05-07 | 0.58 | 0.60 | 0.58 | 0.60 | 39 | +5.08% |
| 2026-05-06 | 0.59 | 0.60 | 0.57 | 0.57 | 2K | -4.36% |
| 2026-05-05 | 0.60 | 0.60 | 0.60 | 0.60 | 2 | +0.27% |
| 2026-05-04 | 0.60 | 0.65 | 0.60 | 0.60 | 3K | -1.59% |
| 2026-05-01 | 0.60 | 0.60 | 0.60 | 0.60 | 100 | -3.97% |
| 2026-04-30 | 0.61 | 0.63 | 0.61 | 0.63 | 5K | +5.81% |
| 2026-04-29 | 0.60 | 0.60 | 0.60 | 0.60 | 7 | -6.97% |
| 2026-04-28 | 0.64 | 0.64 | 0.64 | 0.64 | 5K | +0.84% |
| 2026-04-27 | 0.63 | 0.63 | 0.63 | 0.63 | 8K | +6.65% |
| 2026-04-24 | 0.60 | 0.60 | 0.60 | 0.60 | 655 | -1.10% |
| 2026-04-22 | 0.60 | 0.60 | 0.60 | 0.60 | 1K | -3.99% |
| 2026-04-21 | 0.63 | 0.63 | 0.63 | 0.63 | 99 | -1.24% |
| 2026-04-17 | 0.60 | 0.63 | 0.60 | 0.63 | 6K | +6.12% |
| 2026-04-15 | 0.60 | 0.60 | 0.60 | 0.60 | 3K | -1.48% |
| 2026-04-14 | 0.60 | 0.64 | 0.60 | 0.61 | 39K | -2.10% |
| 2026-04-13 | 0.60 | 0.62 | 0.60 | 0.62 | 10K | +3.68% |
| 2026-04-10 | 0.60 | 0.60 | 0.60 | 0.60 | 8K | -4.32% |
| 2026-04-09 | 0.60 | 0.63 | 0.60 | 0.63 | 41K | -1.57% |
| 2026-04-08 | 0.62 | 0.64 | 0.62 | 0.64 | 23K | +0.79% |
| 2026-04-07 | 0.61 | 0.67 | 0.60 | 0.63 | 122K | +5.88% |
| 2026-04-06 | 0.59 | 0.59 | 0.59 | 0.59 | 50 | 0.00% |
| 2026-04-02 | 0.59 | 0.59 | 0.59 | 0.59 | 359 | -0.02% |
| 2026-04-01 | 0.60 | 0.60 | 0.59 | 0.60 | 3K | -1.15% |
| 2026-03-31 | 0.62 | 0.62 | 0.60 | 0.60 | 2K | +0.17% |
| 2026-03-30 | 0.61 | 0.63 | 0.60 | 0.60 | 8K | -1.80% |
| 2026-03-27 | 0.61 | 0.61 | 0.61 | 0.61 | 5K | -12.57% |
| 2026-03-25 | 0.67 | 0.70 | 0.67 | 0.70 | 100 | -0.14% |
| 2026-03-24 | 0.66 | 0.73 | 0.66 | 0.70 | 15K | -0.95% |
| 2026-03-23 | 0.71 | 0.71 | 0.71 | 0.71 | 8K | +17.95% |
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Start ComparisonSYBX — Frequently Asked Questions
Quick answers to the most common questions about buying SYBX stock.
How has SYBX stock performed recently?
SYBX declined -48.8% over the past year, below its 5-year annualized CAGR of -57.8%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is SYBX's all-time high price?
Synlogic, Inc. reached $478.80 on 2016-05-03. The 52-week high is $1.96. Current 1-year return of -48.8% places the stock further from historical peaks.
Where can I download SYBX historical price data?
This page provides SYBX daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2015-2026, downloadable in CSV format.