Synlogic, Inc. (SYBX) Stock Price History
Historical prices from 2015 to 2026
- 1M
- +18.3%
- 3M
- +14.5%
- YTD
- -39.3%
- 1Y
- -41.3%
- 3Y
- -56.1%
- 5Y
- -59.4%
Loading 10-year price history...
SYBX Historical Performance
SYBX Annual Returns
Year-by-year price performance · 2015–2026
- 2015 annual price return
- +1237.3%
- 2016 annual price return
- +334.8%
- 2017 annual price return
- -23.0%
- 2018 annual price return
- -35.1%
- 2019 annual price return
- -66.1%
- 2020 annual price return
- -19.4%
- 2021 annual price return
- +10.0%
- 2022 annual price return
- -68.6%
- 2023 annual price return
- -65.4%
- 2024 annual price return
- -68.7%
- 2025 annual price return
- -21.1%
- 2026 annual price return
- -47.0%
SYBX Stock Price Trajectory (2015–2026)
As of June 23, 2026, Synlogic, Inc. (SYBX) trades at $0.62, representing a -41.3% return over the past year. The stock has delivered a -98.9% total return over five years (-59.4% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $478.80 on May 3, 2016. From this peak, SYBX has corrected -99.9%, currently trading 42% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers IMVT (+122.8% 1Y), ACMR (+336.2% 1Y), and AGEN (-32.9% 1Y), SYBX has underperformed the peer group average. Compare SYBX vs IMVT →
SYBX Historical Price Data · from 2015
Rows 1–50 of 2,683| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-22 | 0.60 | 0.72 | 0.60 | 0.62 | 2K | -12.61% |
| 2026-06-18 | 0.60 | 0.71 | 0.60 | 0.71 | 200 | 0.00% |
| 2026-06-17 | 0.60 | 0.72 | 0.60 | 0.71 | 801 | +15.45% |
| 2026-06-16 | 0.70 | 0.70 | 0.60 | 0.61 | 10K | -16.89% |
| 2026-06-12 | 0.69 | 0.74 | 0.67 | 0.74 | 321 | -1.33% |
| 2026-06-11 | 0.60 | 0.75 | 0.60 | 0.75 | 287 | -5.06% |
| 2026-06-10 | 0.60 | 0.79 | 0.60 | 0.79 | 10K | +23.44% |
| 2026-06-08 | 0.60 | 0.64 | 0.60 | 0.64 | 67 | -1.54% |
| 2026-06-05 | 0.72 | 0.72 | 0.65 | 0.65 | 103 | -7.14% |
| 2026-06-03 | 0.70 | 0.70 | 0.60 | 0.70 | 1K | +16.67% |
| 2026-06-02 | 0.70 | 0.70 | 0.60 | 0.60 | 1K | -13.04% |
| 2026-06-01 | 0.69 | 0.69 | 0.69 | 0.69 | 14K | +2.99% |
| 2026-05-29 | 0.59 | 0.67 | 0.59 | 0.67 | 1K | +8.06% |
| 2026-05-28 | 0.60 | 0.67 | 0.60 | 0.62 | 4K | +3.33% |
| 2026-05-26 | 0.63 | 0.63 | 0.60 | 0.60 | 106 | -9.09% |
| 2026-05-21 | 0.59 | 0.66 | 0.59 | 0.66 | 0 | +0.15% |
| 2026-05-20 | 0.59 | 0.66 | 0.59 | 0.66 | 72K | +10.57% |
| 2026-05-19 | 0.59 | 0.66 | 0.59 | 0.60 | 72K | -0.67% |
| 2026-05-18 | 0.60 | 0.60 | 0.60 | 0.60 | 9 | -9.08% |
| 2026-05-15 | 0.65 | 0.66 | 0.61 | 0.66 | 268 | +10.54% |
| 2026-05-14 | 0.60 | 0.60 | 0.60 | 0.60 | 1 | +0.17% |
| 2026-05-13 | 0.60 | 0.60 | 0.60 | 0.60 | 4 | +1.88% |
| 2026-05-12 | 0.58 | 0.58 | 0.58 | 0.58 | 1 | -8.59% |
| 2026-05-11 | 0.62 | 0.65 | 0.60 | 0.64 | 14K | +5.96% |
| 2026-05-08 | 0.62 | 0.62 | 0.60 | 0.60 | 56 | +0.67% |
| 2026-05-07 | 0.58 | 0.60 | 0.58 | 0.60 | 39 | +5.08% |
| 2026-05-06 | 0.59 | 0.60 | 0.57 | 0.57 | 2K | -4.36% |
| 2026-05-05 | 0.60 | 0.60 | 0.60 | 0.60 | 2 | +0.27% |
| 2026-05-04 | 0.60 | 0.65 | 0.60 | 0.60 | 3K | -1.59% |
| 2026-05-01 | 0.60 | 0.60 | 0.60 | 0.60 | 100 | -3.97% |
| 2026-04-30 | 0.61 | 0.63 | 0.61 | 0.63 | 5K | +5.81% |
| 2026-04-29 | 0.60 | 0.60 | 0.60 | 0.60 | 7 | -6.97% |
| 2026-04-28 | 0.64 | 0.64 | 0.64 | 0.64 | 5K | +0.84% |
| 2026-04-27 | 0.63 | 0.63 | 0.63 | 0.63 | 8K | +6.65% |
| 2026-04-24 | 0.60 | 0.60 | 0.60 | 0.60 | 655 | -1.10% |
| 2026-04-22 | 0.60 | 0.60 | 0.60 | 0.60 | 1K | -3.99% |
| 2026-04-21 | 0.63 | 0.63 | 0.63 | 0.63 | 99 | -1.24% |
| 2026-04-17 | 0.60 | 0.63 | 0.60 | 0.63 | 6K | +6.12% |
| 2026-04-15 | 0.60 | 0.60 | 0.60 | 0.60 | 3K | -1.48% |
| 2026-04-14 | 0.60 | 0.64 | 0.60 | 0.61 | 39K | -2.10% |
| 2026-04-13 | 0.60 | 0.62 | 0.60 | 0.62 | 10K | +3.68% |
| 2026-04-10 | 0.60 | 0.60 | 0.60 | 0.60 | 8K | -4.32% |
| 2026-04-09 | 0.60 | 0.63 | 0.60 | 0.63 | 41K | -1.57% |
| 2026-04-08 | 0.62 | 0.64 | 0.62 | 0.64 | 23K | +0.79% |
| 2026-04-07 | 0.61 | 0.67 | 0.60 | 0.63 | 122K | +5.88% |
| 2026-04-06 | 0.59 | 0.59 | 0.59 | 0.59 | 50 | 0.00% |
| 2026-04-02 | 0.59 | 0.59 | 0.59 | 0.59 | 359 | -0.02% |
| 2026-04-01 | 0.60 | 0.60 | 0.59 | 0.60 | 3K | -1.15% |
| 2026-03-31 | 0.62 | 0.62 | 0.60 | 0.60 | 2K | +0.17% |
| 2026-03-30 | 0.61 | 0.63 | 0.60 | 0.60 | 8K | -1.80% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
SYBX — Frequently Asked Questions
Quick answers to the most common questions about buying SYBX stock.
How has SYBX stock performed recently?
SYBX declined -41.3% over the past year, below its 5-year annualized CAGR of -59.4%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is SYBX's all-time high price?
Synlogic, Inc. reached $478.80 on 2016-05-03. The 52-week high is $1.96. Current 1-year return of -41.3% places the stock further from historical peaks.
Where can I download SYBX historical price data?
This page provides SYBX daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2015-2026, downloadable in CSV format.