Syros Pharmaceuticals, Inc. (SYRS) Stock Price History
Historical prices from 2016 to 2026
- 1M
- +300.0%
- 3M
- +300.0%
- YTD
- +100.0%
- 1Y
- +300.0%
- 3Y
- -95.4%
- 5Y
- -90.4%
Loading 10-year price history...
SYRS Historical Performance
SYRS Annual Returns
Year-by-year price performance · 2016–2026
- 2016 annual price return
- -33.0%
- 2017 annual price return
- -22.0%
- 2018 annual price return
- -44.2%
- 2019 annual price return
- +16.7%
- 2020 annual price return
- +52.2%
- 2021 annual price return
- -69.6%
- 2022 annual price return
- -90.6%
- 2023 annual price return
- +120.1%
- 2024 annual price return
- -97.1%
- 2025 annual price return
- -99.9%
- 2026 annual price return
- -50.0%
SYRS Stock Price Trajectory (2016–2026)
As of September 26, 2026, Syros Pharmaceuticals, Inc. (SYRS) trades at $0.00, representing a +300.0% return over the past year. The stock has delivered a -100.0% total return over five years (-90.4% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $243.75 on August 7, 2017. From this peak, SYRS has corrected -100.0%, currently trading 33% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers KYMR (+108.3% 1Y), ARVN (-2.1% 1Y), and IMVT (+112.5% 1Y), SYRS has underperformed the peer group average. Compare SYRS vs KYMR →
SYRS Historical Price Data · from 2016
Rows 1–50 of 2,570| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-09-25 | 0.00 | 0.00 | 0.00 | 0.00 | 4K | 0.00% |
| 2026-09-24 | 0.00 | 0.00 | 0.00 | 0.00 | 4K | 0.00% |
| 2026-09-23 | 0.00 | 0.00 | 0.00 | 0.00 | 3K | 0.00% |
| 2026-09-22 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | 0.00% |
| 2026-09-21 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | 0.00% |
| 2026-09-18 | 0.00 | 0.00 | 0.00 | 0.00 | 876 | -96.67% |
| 2026-09-17 | 0.01 | 0.01 | 0.01 | 0.01 | 4K | +2900.00% |
| 2026-09-16 | 0.00 | 0.00 | 0.00 | 0.00 | 753 | 0.00% |
| 2026-09-15 | 0.00 | 0.00 | 0.00 | 0.00 | 11K | 0.00% |
| 2026-09-14 | 0.00 | 0.00 | 0.00 | 0.00 | 773 | 0.00% |
| 2026-09-11 | 0.00 | 0.00 | 0.00 | 0.00 | 62K | 0.00% |
| 2026-09-10 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | 0.00% |
| 2026-09-08 | 0.00 | 0.00 | 0.00 | 0.00 | 904 | 0.00% |
| 2026-09-04 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | 0.00% |
| 2026-09-03 | 0.00 | 0.00 | 0.00 | 0.00 | 610 | 0.00% |
| 2026-09-02 | 0.00 | 0.00 | 0.00 | 0.00 | 631 | 0.00% |
| 2026-09-01 | 0.00 | 0.00 | 0.00 | 0.00 | 739 | 0.00% |
| 2026-08-31 | 0.00 | 0.00 | 0.00 | 0.00 | 85K | +300.00% |
| 2026-08-28 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | 0.00% |
| 2026-08-27 | 0.00 | 0.00 | 0.00 | 0.00 | 6K | 0.00% |
| 2026-08-26 | 0.00 | 0.00 | 0.00 | 0.00 | 745 | 0.00% |
| 2026-08-24 | 0.00 | 0.00 | 0.00 | 0.00 | 904 | 0.00% |
| 2026-08-21 | 0.00 | 0.00 | 0.00 | 0.00 | 79K | -75.00% |
| 2026-08-20 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | 0.00% |
| 2026-08-19 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | +300.00% |
| 2026-08-18 | 0.00 | 0.00 | 0.00 | 0.00 | 4K | -75.00% |
| 2026-08-17 | 0.00 | 0.00 | 0.00 | 0.00 | 3K | +300.00% |
| 2026-08-14 | 0.00 | 0.00 | 0.00 | 0.00 | 914 | 0.00% |
| 2026-08-13 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | 0.00% |
| 2026-08-12 | 0.00 | 0.00 | 0.00 | 0.00 | 5K | -80.00% |
| 2026-08-11 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | +400.00% |
| 2026-08-10 | 0.00 | 0.00 | 0.00 | 0.00 | 851 | 0.00% |
| 2026-08-07 | 0.00 | 0.00 | 0.00 | 0.00 | 16K | 0.00% |
| 2026-08-06 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | 0.00% |
| 2026-08-05 | 0.00 | 0.00 | 0.00 | 0.00 | 9K | 0.00% |
| 2026-08-04 | 0.00 | 0.00 | 0.00 | 0.00 | 13K | -75.00% |
| 2026-08-03 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | +300.00% |
| 2026-07-31 | 0.00 | 0.00 | 0.00 | 0.00 | 904 | 0.00% |
| 2026-07-30 | 0.00 | 0.00 | 0.00 | 0.00 | 5K | -75.00% |
| 2026-07-29 | 0.00 | 0.00 | 0.00 | 0.00 | 4K | +300.00% |
| 2026-07-28 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | 0.00% |
| 2026-07-24 | 0.00 | 0.00 | 0.00 | 0.00 | 7K | 0.00% |
| 2026-07-23 | 0.00 | 0.00 | 0.00 | 0.00 | 8K | 0.00% |
| 2026-07-22 | 0.00 | 0.00 | 0.00 | 0.00 | 3K | 0.00% |
| 2026-07-21 | 0.00 | 0.00 | 0.00 | 0.00 | 3K | -50.00% |
| 2026-07-20 | 0.00 | 0.00 | 0.00 | 0.00 | 18K | +100.00% |
| 2026-07-17 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | 0.00% |
| 2026-07-16 | 0.00 | 0.00 | 0.00 | 0.00 | 307 | 0.00% |
| 2026-07-15 | 0.00 | 0.00 | 0.00 | 0.00 | 1K | 0.00% |
| 2026-07-14 | 0.00 | 0.00 | 0.00 | 0.00 | 10K | 0.00% |
SYRS Chart Terminal
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Live Breakouts Feed
High-probability breakout stocks crossing their pivot across 5 pattern engines.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
SYRS — Frequently Asked Questions
Quick answers to the most common questions about buying SYRS stock.
How has SYRS stock performed recently?
SYRS returned +300.0% over the past year, beating its 5-year annualized CAGR of -90.4%. The stock trades above its 200-day moving average, confirming the uptrend.
What is SYRS's all-time high price?
Syros Pharmaceuticals, Inc. reached $243.75 on 2017-08-07. The 52-week high is $0.02. Current 1-year return of +300.0% places the stock closer to historical peaks.
Where can I download SYRS historical price data?
This page provides SYRS daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2016-2026, downloadable in CSV format.