Syros Pharmaceuticals, Inc. (SYRS) Stock Price History
Historical prices from 2016 to 2026
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SYRS Historical Performance
Short-Term Returns
SYRS Stock Price Trajectory (2016–2026)
As of May 8, 2026, Syros Pharmaceuticals, Inc. (SYRS) trades at $0.00, representing a -99.0% return over the past year. The stock has delivered a -100.0% total return over five years (-90.5% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $243.75 on August 7, 2017. From this peak, SYRS has corrected -100.0%, currently trading 76% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers KYMR (+190.7% 1Y), ARVN (+52.8% 1Y), and IMVT (+96.1% 1Y), SYRS has underperformed the peer group average. Compare SYRS vs KYMR →
SYRS Historical Price Data (2025–2026)
Showing 30 of 2,467 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-06 | 0.00 | 0.01 | 0.00 | 0.00 | 7K | +100.00% |
| 2026-05-04 | 0.00 | 0.00 | 0.00 | 0.00 | 3K | 0.00% |
| 2026-05-01 | 0.00 | 0.00 | 0.00 | 0.00 | 113 | 0.00% |
| 2026-04-30 | 0.00 | 0.00 | 0.00 | 0.00 | 13K | 0.00% |
| 2026-04-29 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | 0.00% |
| 2026-04-27 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | 0.00% |
| 2026-04-24 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | -50.00% |
| 2026-04-22 | 0.00 | 0.00 | 0.00 | 0.00 | 904 | +100.00% |
| 2026-04-21 | 0.00 | 0.00 | 0.00 | 0.00 | 782 | 0.00% |
| 2026-04-20 | 0.00 | 0.00 | 0.00 | 0.00 | 399 | -33.33% |
| 2026-04-17 | 0.00 | 0.00 | 0.00 | 0.00 | 3K | +50.00% |
| 2026-04-15 | 0.00 | 0.00 | 0.00 | 0.00 | 9K | -33.33% |
| 2026-04-13 | 0.00 | 0.00 | 0.00 | 0.00 | 925 | +50.00% |
| 2026-04-10 | 0.00 | 0.00 | 0.00 | 0.00 | 136 | 0.00% |
| 2026-04-09 | 0.00 | 0.00 | 0.00 | 0.00 | 14K | 0.00% |
| 2026-04-08 | 0.00 | 0.00 | 0.00 | 0.00 | 2K | 0.00% |
| 2026-04-07 | 0.00 | 0.00 | 0.00 | 0.00 | 493 | 0.00% |
| 2026-04-06 | 0.00 | 0.00 | 0.00 | 0.00 | 10K | 0.00% |
| 2026-04-02 | 0.00 | 0.00 | 0.00 | 0.00 | 114 | 0.00% |
| 2026-04-01 | 0.00 | 0.00 | 0.00 | 0.00 | 654 | 0.00% |
| 2026-03-31 | 0.00 | 0.00 | 0.00 | 0.00 | 44K | 0.00% |
| 2026-03-30 | 0.00 | 0.00 | 0.00 | 0.00 | 11K | -33.33% |
| 2026-03-26 | 0.00 | 0.00 | 0.00 | 0.00 | 904 | +50.00% |
| 2026-03-25 | 0.00 | 0.00 | 0.00 | 0.00 | 102 | 0.00% |
| 2026-03-24 | 0.00 | 0.00 | 0.00 | 0.00 | 6K | -75.00% |
| 2026-03-23 | 0.00 | 0.00 | 0.00 | 0.00 | 3K | +300.00% |
| 2026-03-20 | 0.00 | 0.00 | 0.00 | 0.00 | 407 | 0.00% |
| 2026-03-19 | 0.00 | 0.00 | 0.00 | 0.00 | 4K | 0.00% |
| 2026-03-17 | 0.00 | 0.00 | 0.00 | 0.00 | 904 | 0.00% |
| 2026-03-16 | 0.00 | 0.00 | 0.00 | 0.00 | 904 | -75.00% |
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Start ComparisonSYRS — Frequently Asked Questions
Quick answers to the most common questions about buying SYRS stock.
How has SYRS stock performed recently?
SYRS declined -99.0% over the past year, below its 5-year annualized CAGR of -90.5%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is SYRS's all-time high price?
Syros Pharmaceuticals, Inc. reached $243.75 on 2017-08-07. The 52-week high is $0.04. Current 1-year return of -99.0% places the stock further from historical peaks.
Where can I download SYRS historical price data?
This page provides SYRS daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2016-2026, downloadable in CSV format.