Last 23 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -0.92 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 11.58 | 33.40 | 12.65 | 23.53 | 15.29 | 20.61 | 138.05 | 140.88 | 309.49 | 332.74 | 19.17 | 15.61 | 9.37 |
| — | +62.1% | -90.8% | -83.3% | -95.1% | -93.8% | +620.2% | +802.3% | +3202.0% | +17697.6% | +535.9% | +186.1% | +100.9% | |
| P/B Ratio | 0.97 | 1.35 | 1.05 | 1.64 | 1.06 | 0.85 | 1.52 | 2.58 | 2.60 | 6.13 | 3.66 | 1.44 | 0.62 |
| — | +59.0% | -30.8% | -36.4% | -59.1% | -86.1% | -58.4% | +79.6% | +319.9% | +839.5% | +876.4% | +128.3% | +7.7% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | 9.20 | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
TScan Therapeutics, Inc.'s operating margin was -2967.3% in Q1 2026, down 2037.9 pp QoQ and down 1297.6 pp YoY. The trailing four-quarter average of -1657.2% exceeds the current quarter, suggesting the latest result may reflect seasonal weakness or a one-off headwind. Gross margin contracted 70.6% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 72.2% | 29.4% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 82.2% | 100.0% | 100.0% |
| — | -70.6% | 0.0% | 0.0% | 0.0% | 0.0% | +21.6% | 0.0% | 0.0% | 0.0% | +58.0% | 0.0% | +138.9% | |
| Operating Margin | -1315.4% | -2967.3% | -929.4% | -1475.6% | -1256.6% | -1669.7% | -5520.6% | -3109.8% | -6364.6% | -5542.9% | -296.2% | -636.7% | -781.8% |
| — | -77.7% | +83.2% | +52.6% | +80.3% | +69.9% | -1764.0% | -388.4% | -714.1% | -1558.0% | +50.8% | -29.2% | -108.0% | |
| Net Margin | -1256.8% | -2919.1% | -895.1% | -1422.1% | -1201.3% | -1571.9% | -5384.8% | -2849.1% | -5906.9% | -5325.4% | -272.0% | -591.6% | -763.8% |
| — | -85.7% | +83.4% | +50.1% | +79.7% | +70.5% | -1879.8% | -381.6% | -673.3% | -1505.7% | +55.0% | -22.5% | -105.2% |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -71.3% | -26.1% | -17.2% | -22.3% | -19.1% | -15.1% | -15.2% | -12.3% | -16.7% | -22.0% | -12.3% | -12.8% | -17.9% |
| — | -72.2% | -12.9% | -80.4% | -14.1% | +31.3% | -24.2% | +3.5% | +6.5% | +13.4% | +29.2% | +2.2% | -64.4% | |
| ROA | -43.3% | -13.3% | -9.4% | -12.7% | -11.7% | -9.7% | -10.0% | -8.3% | -10.3% | -11.8% | -7.0% | -7.6% | -9.8% |
| — | -37.2% | +6.0% | -54.0% | -13.8% | +17.5% | -43.1% | -9.4% | -4.9% | +2.9% | +32.2% | +26.0% | -4.1% | |
| ROIC | -90.7% | -46.7% | -26.5% | -31.9% | -22.5% | -17.4% | -15.9% | -16.6% | -28.1% | -25.6% | -15.2% | -21.8% | -26.9% |
| — | -168.6% | -66.6% | -91.8% | +19.8% | +32.0% | -4.7% | +23.7% | -4.5% | +0.3% | +57.3% | +78.5% | +74.4% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has weakened 22.2% YoY to 6.65x, tightening the short-term liquidity position.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.76 | 0.62 | 0.76 | 0.66 | 0.55 | 0.46 | 0.40 | 0.39 | 0.37 | 0.75 | 0.61 | 0.51 | 0.46 |
| — | +33.8% | +89.2% | +68.3% | +47.5% | -38.1% | -34.0% | -23.4% | -19.4% | -31.8% | -29.1% | +77.2% | +1056.1% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 8.15 | 6.65 | 8.15 | 6.44 | 7.06 | 8.55 | 8.14 | 9.56 | 7.77 | 5.23 | 6.51 | 6.56 | 6.90 |
| — | -22.2% | +0.1% | -32.6% | -9.1% | +63.3% | +25.0% | +45.7% | +12.6% | -23.1% | -9.2% | -22.9% | -8.5% | |
| Quick Ratio | 8.15 | 6.65 | 8.15 | 6.44 | 7.06 | 8.55 | 8.14 | 9.56 | 7.77 | 5.23 | 6.51 | 6.56 | 6.90 |
| — | -22.2% | +0.1% | -32.6% | -9.1% | +63.3% | +25.0% | +45.7% | +12.6% | -23.1% | -9.2% | -22.9% | -8.5% | |
| Interest Coverage | -49.05 | -42.29 | -31.73 | -50.09 | -52.63 | -49.26 | -44.67 | -30.20 | -32.26 | -30.43 | -22.02 | -22.42 | -23.81 |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 23 years · Updated daily
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Quick answers to the most common questions about buying TCRX stock.
TScan Therapeutics, Inc.'s current P/E is -0.9x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
TScan Therapeutics, Inc.'s current operating margin is -1315.4%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking TScan Therapeutics, Inc.'s business trajectory between earnings reports.