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TNXPTonix Pharmaceuticals Holding Corp.
$13.22$211M
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Tonix Pharmaceuticals Holding Corp. (TNXP) Financials

18Y historyFree accessUpdated daily

Revenue growth of 183.2% in 2026Q1 is offset by extreme margin instability, evidenced by gross margins that fluctuated from -63.8% in 2025Q2 to 71.3% in 2025Q4.

TNXP Income Statement

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly
MetricTTMDec'25Dec'24Dec'23Dec'22Dec'21Dec'20Dec'19Dec'18Dec'17Dec'16Dec'15Dec'14Dec'13Dec'12Dec'11Dec'10Dec'09Dec'08
Sales/Revenue17.56M13.11M10.09M7.77M000000000000000
Revenue Growth %74.84%29.85%29.94%----------------
Cost of Goods Sold8.32M8.56M7.76M4.74M0027K026.32M21.29M38.97M48.16M27.66M10.89M6.66M3.38M017K7.11K
COGS % of Revenue-65.35%76.93%61.03%---------------
Gross Profit9.24M4.54M2.33M3.03M00-27K0-26.32M-21.29M-38.97M-48.16M-27.66M-10.89M-6.66M-3.38M0-17K-7.11K
Gross Margin %52.62%34.65%23.07%38.97%---------------
Gross Profit Growth %-95.02%-23.06%--100%-100%-23.63%45.36%19.09%-74.15%-154%-63.45%-97.17%-100%-139.07%-
Operating Expenses160.42M130.25M139.03M121.41M112.09M92.31M50.48M28.83M26.32M21.29M38.97M48.16M27.66M10.89M6.66M3.38M17.72K13.87K14.02K
OpEx % of Revenue-993.71%1377.35%1562.91%---------------
Selling, General & Admin63.26M85.76M40.1M34.75M30.21M23.47M14.33M10.64M8.76M7.95M10.44M12.66M9.04M6.24M4.08M2.22M13.72K13.87K14.02K
SG&A % of Revenue-654.3%397.28%447.37%---------------
Research & Development55.26M44.49M40.45M86.66M81.88M68.84M36.16M18.19M17.56M13.34M28.53M35.5M18.62M4.65M2.58M1.16M000
R&D % of Revenue-339.41%400.71%1115.54%---------------
Other Operating Expenses2M058.48M000000000001.88K04K00
Operating Income-151.19M-125.7M-136.7M-118.38M-112.09M-92.31M-50.51M-28.83M-26.32M-21.29M-38.97M-48.16M-27.66M-10.89M-6.66M-3.38M-17.72K-30.87K-21.13K
Operating Margin %-861.16%-959.05%-1354.28%-1523.94%---------------
Operating Income Growth %-8.05%-15.48%-5.61%-21.43%-82.76%-75.22%-9.52%-23.63%45.36%19.09%-74.15%-154%-63.45%-97.17%-18961.88%42.58%-46.05%-
EBITDA-149.2M-123.78M-133.28M-114.09M-110.84M-92.26M-50.48M-28.8M-26.27M-21.23M-38.76M-48M-27.62M-10.87M-6.65M-3.37M-17.72K-30.87K-21.13K
EBITDA Margin %-849.85%-944.37%-1320.39%-1468.7%---------------
EBITDA Growth %-113.93%7.13%-16.82%-2.93%-20.13%-82.75%-75.28%-9.65%-23.75%45.24%19.25%-73.79%-154.07%-63.55%-97.29%-18909.41%42.58%-46.05%-
D&A (Non-Cash Add-back)1.99M1.93M3.42M4.29M1.25M50K27K26K54K64K206K161K36K17K14.33K9.3K000
EBIT-150.13M-125.7M-77.74M-118.38M-112.09M-92.31M-50.46M-28.83M-26.32M-21.29M-38.97M-48.16M-27.66M-10.88M-7.84M-3.38M-1.93M-30.87K-21.13K
Net Interest Income4.86M4.06M001.87M25K48K000000000000
Interest Income4.86M4.15M001.87M25K48K0233K168K127K108K40K4K00000
Interest Expense089K000000000004K1.61M0000
Other Income/Expense3.8M1.68M6.67M1.72M1.87M25K48K210K233K168K127K108K40K4K-2.79M-91.58K-1.94M00
Pretax Income-147.39M-124.02M-130.04M-116.66M-110.22M-92.29M-50.46M-28.62M-26.09M-21.12M-38.84M-48.05M-27.62M-10.88M-9.45M-3.47M000
Pretax Margin %-839.52%-946.22%-1288.25%-1501.78%---------------
Income Tax00000000233K-70K-206K-161K-36K-17K1.61M017.72K30.87K21.13K
Effective Tax Rate %0%0%0%0%0%0%0%0%-0.89%0.33%0.53%0.34%0.13%0.16%-17.09%0%---
Net Income-147.39M-124.02M-130.04M-116.66M-110.22M-92.29M-50.46M-28.62M-29.36M-21.12M-38.84M-48.05M-27.62M-10.88M-9.45K-3.47M-17.72K-30.87K-21.13K
Net Margin %-839.52%-946.22%-1288.25%-1501.78%---------------
Net Income Growth %-11.72%4.63%-11.47%-5.84%-19.43%-82.88%-76.33%2.51%-38.97%45.62%19.17%-74.01%-153.73%-115074.6%99.73%-19478.61%42.58%-46.05%-
Net Income (Continuing)-147.39M-124.02M-130.04M-116.66M-110.22M-92.29M-50.46M-28.62M-26.09M-21.12M-38.84M-48.05M-27.62M-10.88M-9.45K-3.47M-1.96M-30.87K-21.13K
Discontinued Operations0000000000000000000
Minority Interest0000000000000000000
EPS (Diluted)-10.75-14.57-176.60-6368.84-811.68-163968.00-5056.00-3866.00-18064.62-54023.02-199189.74-511212.77-511407.41-375310.34-945000.00-578352.17-999999.00-30867.00-21134.00
EPS Growth %99.24%91.75%97.23%-684.65%99.5%-3143.04%-30.78%78.6%66.56%72.88%61.04%0.04%-36.26%60.28%-63.4%70.56%-6264.3%-46.05%-
EPS (Basic)--14.57-176.60-6368.84-811.68-163968.00-5056.00-3866.00-18064.62-54023.02-199189.74-511212.77-511407.41-375310.34-945000.00-578352.17-999999.00-30867.00-21134.00
Diluted Shares Outstanding13.71M8.51M2.26M1.83M3.07M5632.56M804.2K162.5K39.1K19.5K9.4K5.4K2.9K1K600100100100
Basic Shares Outstanding13.71M8.51M2.26M1.83M3.07M5632.56M804.2K162.5K39.1K19.5K9.4K5.4K2.9K1K600100100100
Dividend Payout Ratio-------------------

Key Metrics

Growth RegimeAccelerating
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Clinical trial failure risk

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Revenue Surge Masks Commercial Fragility

According to recent quarterly filings, Tonix reported a significant revenue acceleration to $6.9 million in 2026Q1, representing a 183.2% year-over-year increase, though this growth appears driven by volatile commercial product sales rather than a sustainable, high-margin expansion of the company's core clinical-stage pipeline assets.

The sharp uptick in top-line performance suggests a potential shift in commercial execution, yet the lack of consistent organic growth in previous periods warrants caution. Investors should monitor whether this revenue trajectory can be maintained without further dilutive financing, as the current scale remains insufficient to offset the company's massive R&D expenditure.

Structural Margin Volatility Remains High

As reported in financial statements, Tonix's gross margin has exhibited extreme instability, fluctuating from a negative 63.8% in 2025Q2 to a peak of 71.3% in 2025Q4, highlighting the company's lack of pricing power and reliance on low-margin, acquired migraine assets that struggle to achieve consistent profitability.

The erratic nature of these margins suggests that the company's manufacturing and royalty obligations are not yet optimized for scale. This structural weakness implies that until the lead CNS pipeline assets reach commercialization, gross profitability will likely remain highly sensitive to product mix and third-party manufacturing cost fluctuations.

Operating Leverage Remains Severely Constrained

Based on the provided income statement data, Tonix continues to demonstrate a lack of operating leverage, with operating losses reaching $41.5 million in 2026Q1 as SG&A and R&D expenses consistently outpace the company's ability to generate meaningful gross profit from its current commercial portfolio.

The persistent gap between operating expenses and revenue indicates that the company is in a deep investment phase, prioritizing pipeline development over immediate operational efficiency. This trend suggests that the firm remains entirely dependent on external capital to fund its ongoing clinical operations, leaving little room for error in its R&D milestones.

R&D Intensity Drives Cash Burn

Analysis of the company's cost structure reveals that R&D remains the primary driver of expenditure, with quarterly outlays frequently exceeding $15 million, which underscores the high-stakes nature of Tonix's diversified pipeline strategy and the significant capital required to maintain its various clinical-stage programs.

The company's expense discipline appears secondary to the necessity of funding multiple concurrent clinical trials, which may indicate a lack of strategic focus. Investors should consider that this high fixed-cost base creates a precarious financial position, where any delay in clinical progress could rapidly accelerate the depletion of existing cash reserves.

Dilution Risk Overshadows Clinical Progress

While recent clinical data for TNX-102 SL provides a potential path forward, the historical trend of massive share count expansion and persistent net losses suggests that the company's equity value may remain under pressure from ongoing dilution required to sustain its broad, capital-intensive R&D portfolio.

Short-term observers might focus on the disconnect between the company's clinical milestones and its deteriorating per-share metrics. The reliance on equity markets to bridge the gap between operating cash burn and revenue generation warrants further investigation into the long-term viability of the current capital allocation strategy.

TNXP — Frequently Asked Questions

Quick answers to the most common questions about buying TNXP stock.

What was Tonix Pharmaceuticals Holding Corp.'s (TNXP) revenue in 2025?

For fiscal year 2025, Tonix Pharmaceuticals Holding Corp. (TNXP) reported total revenue of $13.1M.

Is Tonix Pharmaceuticals Holding Corp. (TNXP) profitable?

Tonix Pharmaceuticals Holding Corp. (TNXP) reported a net loss of $124.0M for the fiscal year ending 2025.

What is Tonix Pharmaceuticals Holding Corp.'s operating profit margin?

Tonix Pharmaceuticals Holding Corp. (TNXP) reported an operating income of $-125.7M, resulting in an operating profit margin of -959.1%. This margin reflects the operational efficiency of the business before interest and taxes.

What is Tonix Pharmaceuticals Holding Corp.'s gross profit and gross margin?

Tonix Pharmaceuticals Holding Corp. (TNXP) generated $4.5M in gross profit for the year, representing a gross profit margin of 34.7%. This demonstrates the company's core pricing power and production efficiency.