Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in TNYA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | VANGUARD CAPITAL MANAGEMENT LLC | 8.5M | $5.9M | — | 5.091% | 0.00% |
| 2 | MILLENNIUM MANAGEMENT LLC | 5.5M | $3.8M | +18.2% | 3.275% | 0.00% |
| 3 | CITADEL ADVISORS LLC | 4.4M | $3.0M | +1.2% | 2.627% | 0.00% |
| 4 | Empery Asset Management, LP | 4.3M | $3.0M | -20.8% | 2.573% | 3.58% |
| 5 | RENAISSANCE TECHNOLOGIES LLC | 3.7M | $2.6M | +100.6% | 2.229% | 0.00% |
| 6 | BlackRock, Inc. | 3.7M | $2.6M | -6.2% | 2.223% | 0.00% |
| 7 | MARSHALL WACE, LLP | 2.7M | $1.9M | +92.4% | 1.624% | 0.00% |
| 8 | Kalehua Capital Management LLC | 2.0M | $1.4M | 0.0% | 1.200% | 1.17% |
| 9 | Burkehill Global Management, LP | 2.0M | $1.4M | 0.0% | 1.200% | 0.07% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 1.6M | $1.1M | +30.7% | 0.936% | 0.00% |
| 11 | ADAR1 Capital Management, LLC | 1.5M | $1.0M | +0.2% | 0.905% | 0.07% |
| 12 | TWO SIGMA INVESTMENTS, LP | 1.3M | $887K | +1.1% | 0.768% | 0.00% |
| 13 | Euclidean Capital LLC | 1.0M | $703K | 0.0% | 0.610% | 0.18% |
| 14 | VANGUARD FIDUCIARY TRUST CO | 1.0M | $703K | — | 0.610% | 0.00% |
| 15 | Alphabet Inc. | 916K | $632K | 0.0% | 0.550% | 0.02% |
| 16 | Raiffeisen Bank International AG | 1.0M | $620K | +11.1% | 0.600% | 0.01% |
| 17 | Mirador Capital Partners LP | 887K | $614K | +52.3% | 0.532% | 0.09% |
| 18 | STATE STREET CORP | 709K | $491K | +59.0% | 0.425% | 0.00% |
| 19 | UBS Group AG | 665K | $460K | +14.8% | 0.399% | 0.00% |
| 20 | StepStone Group LP | 462K | $319K | 0.0% | 0.277% | 0.15% |
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 433K | $299K | -0.7% | 0.260% | 0.00% |
| 22 | Casdin Capital, LLC | 362K | $251K | 0.0% | 0.217% | 0.02% |
| 23 | Squarepoint Ops LLC | 348K | $241K | — | 0.209% | 0.00% |
| 24 | NORTHERN TRUST CORP | 311K | $215K | +28.6% | 0.186% | 0.00% |
| 25 | MORGAN STANLEY | 269K | $186K | +28.8% | 0.161% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in TNYA — a direct measure of their conviction.
Filings activity in TNYA during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 102 | +6.3% | 30.38% | 10.03 pp | $36M | 25% |
| Q4 2025 | 96 | +10% | 40.41% | 5.80 pp | $48M | 13% |
| Q3 2025 | 87 | 1.1% | 46.21% | +30.17 pp | $55M | +188% |
| Q2 2025 | 88 | 17% | 16.04% | 6.93 pp | $19M | 30% |
| Q1 2025 | 106 | +23% | 22.97% | 29.18 pp | $27M | 56% |
| Q4 2024 | 86 | 9.5% | 52.15% | 32.11 pp | $62M | 38% |
| Q3 2024 | 95 | +0.0% | 84.26% | 47.87 pp | $100M | 36% |
| Q2 2024 | 95 | — | 132.13% | — | $157M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying TNYA stock.
Based on Q1 2026 13F filings, institutional ownership of Tenaya Therapeutics, Inc. stands at 30.4%, held across 102 reporting institutions.
VANGUARD CAPITAL MANAGEMENT LLC is the largest reported institutional holder of TNYA, with approximately 8,482,288 shares worth $0.01B as of Q1 2026.
Yes — 5 widely-followed marquee investors appear among the top 25 institutional holders of TNYA, including MILLENNIUM MANAGEMENT LLC, CITADEL ADVISORS LLC, RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for TNYA is 59 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
29 institutions opened new positions in TNYA during Q1 2026, while 23 fully exited. 27 added to existing positions and 45 trimmed.
TNYA institutional ownership fell by 10.03 percentage points quarter-over-quarter, with a net change of +6 holders.
The top 10 institutions account for 73.6% of all reported 13F value in TNYA, and the top 25 account for 94.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Tenaya Therapeutics, Inc. (TNYA) Institutional Ownership