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TWST logoTwist Bioscience Corporation(TWST)Earnings, Financials & Key Ratios

TWST•NASDAQ
$59.53
$3.71B mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryDiagnostics & ResearchSub-IndustryLab Consumables and Sample Preparation
AboutTwist Bioscience Corporation, a synthetic biology company, manufactures and sells synthetic DNA-based products. The company's DNA synthesis platform enables the manufacturing of synthetic DNA by writing DNA on a silicon chip. It offers synthetic DNA-based products, including synthetic genes, tools for sample preparation, antibody libraries for drug discovery and development, and DNA as a digital data storage medium. The company has collaboration agreements with Victorian Clinical Genetic Services; Vivlion GmbH.; Kyowa Kirin Pharmaceutical Research, Inc.; deepCDR Biologics AG; and Centogene N.V to develop advanced sequencing tools. It also has a research collaboration with Boehringer Ingelheim International GmbH to use proprietary antibody libraries to discover therapeutic antibodies against multiple targets. Twist Bioscience Corporation was incorporated in 2013 and is headquartered in South San Francisco, California.Show more
  • Revenue$377M+20.3%
  • EBITDA-$111M+41.2%
  • Net Income-$78M+62.8%
  • EPS (Diluted)-1.30+63.9%
  • Gross Margin50.72%+19.0%
  • EBITDA Margin-29.58%+51.1%
  • Operating Margin-36.18%+48.7%
  • Net Margin-20.63%+69.1%
  • ROE-16.43%+56.9%
  • ROIC-26.94%+38.0%
  • Debt/Equity0.29+61.4%
Technical→

TWST Key Insights

Twist Bioscience Corporation (TWST) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 92 (top 8%)
  • ✓Strong 5Y sales CAGR of 33.1%

✗Weaknesses

  • ✗Negative free cash flow

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

TWST Price & Volume

Twist Bioscience Corporation (TWST) stock price & volume — 10-year historical chart

Loading chart...

TWST Growth Metrics

Twist Bioscience Corporation (TWST) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years33.11%
3 Years22.76%
TTM17.77%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM57.48%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM59.2%

Return on Capital

10 Years-51.62%
5 Years-29.91%
3 Years-29.32%
Last Year-24.92%

TWST Recent Earnings

Twist Bioscience Corporation (TWST) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 8/12 qtrs (67%)
Q2 2026Latest
May 4, 2026
EPS
$0.71
Est $0.49
-44.9%
Revenue
$111M
Est $108M
+2.9%
Q1 2026
Feb 2, 2026
EPS
$0.50
Est $0.48
-4.2%
Revenue
$104M
Est $102M
+1.8%
Q4 2025
Nov 14, 2025
EPS
$0.45
Est $0.50
+10.0%
Revenue
$99M
Est $97M
+1.7%
Q3 2025
Aug 4, 2025
EPS
$0.47
Est $0.54
+13.0%
Revenue
$96M
Est $97M
-1.4%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 4, 2026
$0.71vs $0.49-44.9%
$111Mvs $108M+2.9%
Q1 2026Feb 2, 2026
$0.50vs $0.48-4.2%
$104Mvs $102M+1.8%
Q4 2025Nov 14, 2025
$0.45vs $0.50+10.0%
$99Mvs $97M+1.7%
Q3 2025Aug 4, 2025
$0.47vs $0.54+13.0%
$96Mvs $97M-1.4%
Based on last 12 quarters of dataView full earnings history →

TWST Peer Comparison

Twist Bioscience Corporation (TWST) competitors in Lab Consumables and Sample Preparation — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ILMN logoILMNIllumina, Inc.Direct Competitor21.66B142.5826.16-0.78%19.43%32.84%0.94
PACB logoPACBPacific Biosciences of California, Inc.Direct Competitor516.17M1.71-1.60-23.19%-325.8%-13.95%1.33
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.32B32.33-39.92120.01%-57.24%-7.31%0.24
NTLA logoNTLAIntellia Therapeutics, Inc.Direct Competitor1.61B13.85-3.64-100%-61.47%0.14
GH logoGHGuardant Health, Inc.Product Competitor11.53B92.25-27.7932.88%-44.18%
EXAS logoEXASExact Sciences CorporationProduct Competitor20.02B104.91-95.3717.69%-6.4%-8.66%1.05
CDNA logoCDNACareDx, IncProduct Competitor1.08B20.94-52.3513.79%-1.98%-2.61%0.06
NTRA logoNTRANatera, Inc.Product Competitor29.58B215.09-140.5856.75%-14.61%-24.69%0.16

Compare TWST vs Peers

Twist Bioscience Corporation (TWST) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ILMN

Most directly comparable listed peer for TWST.

Scale Benchmark

vs TMO

Larger-name benchmark to compare TWST against a more recognizable public peer.

Peer Set

Compare Top 5

vs ILMN, PACB, BEAM, NTLA

TWST Income Statement

Twist Bioscience Corporation (TWST) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemSep'17Sep'18Sep'19Sep'20Sep'21Sep'22Sep'23Sep'24Sep'25TTM
Sales/Revenue10.77M25.43M54.38M90.1M132.33M203.56M245.11M312.97M376.57M409.48M
Revenue Growth %374.53%136.16%113.89%65.67%46.87%53.83%20.41%27.69%20.32%17.77%
Cost of Goods Sold24.02M32.19M47.43M61.41M80.62M119.33M155.38M179.63M185.57M196.25M
COGS % of Revenue223.09%126.59%87.2%68.15%60.92%58.62%63.39%57.39%49.28%-
Gross Profit
-13.25M▲ 0%
-6.76M▲ 49.0%
6.96M▲ 202.9%
28.69M▲ 312.3%
51.71M▲ 80.2%
84.23M▲ 62.9%
89.73M▲ 6.5%
133.35M▲ 48.6%
191M▲ 43.2%
213.23M▲ 0%
Gross Margin %-123.09%-26.59%12.8%31.85%39.08%41.38%36.61%42.61%50.72%52.07%
Gross Profit Growth %-85.3%48.98%202.91%312.33%80.22%62.89%6.52%48.61%43.23%-
Operating Expenses45.23M63.8M115.81M168.77M204.44M319.01M306.89M354.18M327.26M352.05M
OpEx % of Revenue420.07%250.9%212.94%187.32%154.49%156.71%125.2%113.17%86.91%-
Selling, General & Admin26.06M43.45M80.13M103.27M135.9M212.95M189.74M218.4M246.98M272.95M
SG&A % of Revenue242.04%170.88%147.33%114.61%102.7%104.61%77.41%69.78%65.59%-
Research & Development19.17M20.35M35.68M43.01M69.07M120.31M106.89M90.85M80.28M71.89M
R&D % of Revenue178.03%80.02%65.61%47.73%52.2%59.1%43.61%29.03%21.32%-
Other Operating Expenses-55K-121K-265K22.5M-534K-14.24M10.26M44.93M01000K
Operating Income
-58.48M▲ 0%
-70.56M▼ 20.7%
-108.85M▼ 54.3%
-140.08M▼ 28.7%
-152.73M▼ 9.0%
-234.78M▼ 53.7%
-217.16M▲ 7.5%
-220.83M▼ 1.7%
-136.26M▲ 38.3%
-138.82M▲ 0%
Operating Margin %-543.16%-277.5%-200.15%-155.47%-115.41%-115.33%-88.6%-70.56%-36.18%-33.9%
Operating Income Growth %-33.96%-20.65%-54.27%-28.69%-9.03%-53.72%7.5%-1.69%38.3%-
EBITDA-53.46M-64.83M-102.54M-133.4M-142.98M-218.26M-187.85M-189.4M-111.41M-114.63M
EBITDA Margin %-496.53%-254.97%-188.54%-148.06%-108.04%-107.22%-76.64%-60.52%-29.58%-27.99%
EBITDA Growth %-35.59%-21.27%-58.16%-30.1%-7.18%-52.66%13.93%-0.83%41.18%33.91%
D&A (Non-Cash Add-back)5.02M5.73M6.31M6.68M9.75M16.51M29.31M31.43M24.85M24.19M
EBIT-58.13M-69.68M-106.08M-138.76M-153.66M-228.19M-203.46M-208.14M-76.95M-82.42M
Net Interest Income-493K-314K1.74M712K68K2.98M14.36M15.31M11.36M9.21M
Interest Income412K999K3.03M1.5M435K3.06M14.37M15.34M11.36M9.21M
Interest Expense905K1.31M1.29M787K367K80K5K29K00
Other Income/Expense-548K-435K1.47M530K-1.3M6.5M13.69M12.66M59.31M58.28M
Pretax Income
-59.03M▲ 0%
-70.99M▼ 20.3%
-107.38M▼ 51.2%
-139.55M▼ 30.0%
-154.03M▼ 10.4%
-228.27M▼ 48.2%
-203.47M▲ 10.9%
-208.17M▼ 2.3%
-76.95M▲ 63.0%
-80.53M▲ 0%
Pretax Margin %-548.25%-279.21%-197.44%-154.88%-116.39%-112.14%-83.01%-66.51%-20.43%-19.67%
Income Tax280K242K292K382K-1.93M-10.41M1.15M560K719K743K
Effective Tax Rate %-0.47%-0.34%-0.27%-0.27%1.25%4.56%-0.57%-0.27%-0.93%-0.92%
Net Income
-59.31M▲ 0%
-71.24M▼ 20.1%
-107.67M▼ 51.1%
-139.93M▼ 30.0%
-152.1M▼ 8.7%
-217.86M▼ 43.2%
-204.62M▲ 6.1%
-208.73M▼ 2.0%
-77.67M▲ 62.8%
-81.28M▲ 0%
Net Margin %-550.85%-280.16%-197.98%-155.31%-114.94%-107.02%-83.48%-66.69%-20.63%-19.85%
Net Income Growth %-34.53%-20.11%-51.14%-29.96%-8.7%-43.24%6.08%-2.01%62.79%57.48%
Net Income (Continuing)-59.31M-71.24M-107.67M-139.93M-152.1M-217.86M-204.62M-208.73M-77.67M-81.28M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-3.16▲ 0%
-2.68▲ 15.2%
-3.92▼ 46.3%
-3.57▲ 8.9%
-3.15▲ 11.8%
-4.04▼ 28.3%
-3.60▲ 10.9%
-3.60▲ 0.0%
-1.30▲ 63.9%
-1.32▲ 0%
EPS Growth %-34.47%15.19%-46.27%8.93%11.76%-28.25%10.89%0%63.89%59.2%
EPS (Basic)-3.16-2.68-3.92-3.57-3.15-4.04-3.60-3.60-1.30-
Diluted Shares Outstanding18.78M26.61M27.46M39.19M48.25M53.88M56.88M58.02M59.81M61.7M
Basic Shares Outstanding18.78M26.61M27.46M39.19M48.25M53.88M56.88M58.02M59.81M61.7M
Dividend Payout Ratio----------

TWST Balance Sheet

Twist Bioscience Corporation (TWST) balance sheet — assets, liabilities & shareholders' equity

Line itemSep'17Sep'18Sep'19Sep'20Sep'21Sep'22Sep'23Sep'24Sep'25TTM
Total Current Assets67.87M95.67M160.13M334.87M546.5M596.48M424.26M346.78M332.97M323.44M
Cash & Short-Term Investments62.2M80.76M138.11M290M477.86M504.97M336.41M276.4M232.43M171.67M
Cash Only31.23M80.76M46.73M93.67M465.83M378.69M286.47M226.32M183.05M122.67M
Short-Term Investments30.98M091.37M196.34M12.03M126.28M49.94M50.08M49.38M49M
Accounts Receivable2.35M5.42M12.1M25.43M28.55M40.29M44.06M34.9M57.02M64.15M
Days Sales Outstanding79.5377.7981.2310378.7472.2565.6240.755.2749.34
Inventory1.83M6.03M7.33M12.29M31.8M39.31M32.06M24.08M28.31M33.52M
Days Inventory Outstanding27.7668.3556.4173.05143.97120.2375.3248.9355.6856.11
Other Current Assets03.47M0951K0011.72M11.4M054.1M
Total Non-Current Assets17.79M20.12M26.86M64.01M155.6M364.9M352.15M267.55M308.89M352.77M
Property, Plant & Equipment14.83M12.33M20.84M59.16M105.7M214.39M203.36M161.35M151.66M181.88M
Fixed Asset Turnover0.73x2.06x2.61x1.52x1.25x0.95x1.21x1.94x2.48x2.49x
Goodwill1.14M1.14M1.14M1.14M22.43M85.81M85.81M85.81M82.19M82.19M
Intangible Assets920K712K508K307K18.26M59.74M54.48M14.48M13.43M13M
Long-Term Investments202K579K579K0000054.34M235.27M
Other Non-Current Assets896K5.94M4.38M3.4M9.2M4.96M8.49M5.91M7.28M24.25M
Total Assets
85.66M▲ 0%
115.79M▲ 35.2%
186.99M▲ 61.5%
398.88M▲ 113.3%
702.1M▲ 76.0%
961.38M▲ 36.9%
776.4M▼ 19.2%
614.32M▼ 20.9%
641.86M▲ 4.5%
676.21M▲ 0%
Asset Turnover0.13x0.22x0.29x0.23x0.19x0.21x0.32x0.51x0.59x0.63x
Asset Growth %12.02%35.18%61.49%113.31%76.02%36.93%-19.24%-20.88%4.48%23.72%
Total Current Liabilities9.48M18.54M30.35M36.03M63.05M90.66M73.32M71.01M91.41M119.98M
Accounts Payable2.85M7.53M9.76M4.83M14.9M20.09M14.05M1.63M11.09M14.68M
Days Payables Outstanding43.2985.475.1128.7167.4661.4633.013.3121.8223.37
Short-Term Debt02.5M3.33M3.33M1.55M00013.82M10.44M
Deferred Revenue (Current)07.57M16.44M01.09M3.48M02.13M6.88M22.23M
Other Current Liabilities3.16M3.1M817K2.61M28.42M39.62M18.56M34.61M23.77M94.85M
Current Ratio7.16x5.16x5.28x9.29x8.67x6.58x5.79x4.88x3.64x3.64x
Quick Ratio6.97x4.84x5.03x8.95x8.16x6.15x5.35x4.54x3.33x3.33x
Cash Conversion Cycle6460.7562.53147.33155.26131.02107.9386.3289.1382.08
Total Non-Current Liabilities209.54M298.68M4.56M26.59M58.22M81.33M79.65M70.63M77.5M101.14M
Long-Term Debt9.15M7.22M4.4M1.4M000061.75M85.4M
Capital Lease Obligations00024.84M53.16M81.27M79.17M70.22M61.75M210.21M
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities200.38M291.46M158K351K5.07M60K475K407K-46M-84.64M
Total Liabilities219.01M317.21M34.91M62.62M121.28M171.99M152.97M141.63M168.9M221.12M
Total Debt9.15M9.72M7.73M35.98M62.92M94.91M94.07M85.03M137.32M95.84M
Net Debt-22.07M-71.04M-39M-57.69M-402.91M-283.77M-192.4M-141.29M-45.73M-26.83M
Debt / Equity--0.05x0.11x0.11x0.12x0.15x0.18x0.29x0.29x
Debt / EBITDA----------0.84x
Net Debt / EBITDA---------0.23x
Interest Coverage-64.23x-53.07x-81.98x-176.32x-418.69x-2852.43x-40692.20x-7177.14x--
Total Equity
-133.36M▲ 0%
-201.42M▼ 51.0%
152.08M▲ 175.5%
336.26M▲ 121.1%
580.82M▲ 72.7%
789.38M▲ 35.9%
623.43M▼ 21.0%
472.69M▼ 24.2%
472.96M▲ 0.1%
455.09M▲ 0%
Equity Growth %-74.07%-51.04%175.5%121.11%72.73%35.91%-21.02%-24.18%0.06%0.86%
Book Value per Share-7.10-7.575.548.5812.0414.6510.968.157.917.38
Total Shareholders' Equity-133.36M-201.42M152.08M336.26M580.82M789.38M623.43M472.69M472.96M455.09M
Common Stock0000000001K
Retained Earnings-139.62M-210.85M-318.52M-458.45M-610.55M-828.42M-1.03B-1.24B-1.32B-1.39B
Treasury Stock0000000000
Accumulated OCI33K87K181K87K546K-1.84M-756K-522K-627K-639K
Minority Interest0000000000

TWST Cash Flow Statement

Twist Bioscience Corporation (TWST) cash flow — operating, investing & free cash flow history

Line itemSep'17Sep'18Sep'19Sep'20Sep'21Sep'22Sep'23Sep'24Sep'25TTM
Cash from Operations-51.3M-66.16M-87.94M-142.25M-112.24M-124.39M-142.47M-64.09M-47.63M-47.63M
Operating CF Margin %-476.47%-260.21%-161.69%-157.89%-84.82%-61.1%-58.13%-20.48%-12.65%-
Operating CF Growth %-32.93%-28.97%-32.91%-61.77%21.1%-10.82%-14.54%55.01%25.69%49.92%
Net Income-59.31M-71.24M-107.67M-139.93M-152.1M-217.86M-204.62M-208.73M-77.67M-81.28M
Depreciation & Amortization5.02M5.73M6.11M6.68M9.75M16.51M29.31M31.43M24.85M24.68M
Stock-Based Compensation1.89M2.96M11.17M17.1M37M79.66M30.28M50.92M64.46M64.35M
Deferred Taxes768K42K-1.06M-214K00-410K000
Other Non-Cash Items458K562K515K-707K2.49M2.66M3.98M46.86M-46.66M-48.31M
Working Capital Changes-129K-4.22M3M-25.18M-9.38M-5.36M-1.01M15.41M-12.61M-15.03M
Change in Receivables-1.62M-3.07M-6.68M-14.27M-2.2M-9.62M-4.32M8.44M-22.38M-14.54M
Change in Inventory-599K-4.2M-1.3M-4.96M-19.49M-7.54M7.24M7.99M-4.23M-12.65M
Change in Payables560K3.76M3.28M-5.51M8.54M7.38M-2.51M-11.8M9.33M4.45M
Cash from Investing-9.87M26.87M-104.81M-114.65M156.16M-232.93M50.61M-3.07M-24.76M-44.44M
Capital Expenditures-6.59M-3.69M-14.76M-9.87M-27.06M-101.86M-27.78M-5.08M-28M-39.45M
CapEx % of Revenue61.24%14.5%27.13%10.95%20.45%50.04%11.33%1.62%7.44%-
Acquisitions266K17K21K104.78M-483K-8.16M5.86M02.5M2.5M
Investments----------
Other Investing120K-434K-90.05M-104.78M0-5.75M-5.86M00-5.1M
Cash from Financing63.8M88.82M158.58M303.73M329.18M270.53M911K6.89M28.54M11.84M
Debt Issued (Net)-2M0-2.5M-3.33M-3.33M-1.56M0000
Equity Issued (Net)65.6M90.85M156.21M293.14M313.01M262.07M-4.41M-3.98M13.54M6.26M
Dividends Paid0000000000
Share Repurchases000-2.42M-10.85M-7.75M-4.41M-3.98M-16K-15K
Other Financing205K-2.03M4.87M13.92M19.5M10.02M5.32M10.87M15M5.58M
Net Change in Cash
2.63M▲ 0%
49.53M▲ 1782.6%
-34.14M▼ 168.9%
46.85M▲ 237.2%
373.11M▲ 696.4%
-87.1M▼ 123.3%
-90.98M▼ 4.5%
-60.15M▲ 33.9%
-43.27M▲ 28.1%
-88.09M▲ 0%
Free Cash Flow
-57.9M▲ 0%
-69.85M▼ 20.7%
-102.69M▼ 47.0%
-152.12M▼ 48.1%
-139.31M▲ 8.4%
-226.24M▼ 62.4%
-170.25M▲ 24.7%
-69.17M▲ 59.4%
-75.63M▼ 9.3%
-95.14M▲ 0%
FCF Margin %-537.71%-274.72%-188.83%-168.84%-105.27%-111.14%-69.46%-22.1%-20.08%-23.23%
FCF Growth %-29.17%-20.65%-47.02%-48.13%8.43%-62.41%24.75%59.37%-9.34%-45.27%
FCF per Share-3.08-2.63-3.74-3.88-2.89-4.20-2.99-1.19-1.26-1.26
FCF Conversion (FCF/Net Income)0.86x0.93x0.82x1.02x0.74x0.57x0.70x0.31x0.61x1.17x
Interest Paid702K751K779K438K167K9K0000
Taxes Paid6K179K291K172K101K246K420K344K683K-16K

TWST Key Ratios

Twist Bioscience Corporation (TWST) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)---70.8%-57.31%-33.17%-31.8%-28.97%-38.08%-16.43%-17.46%
Return on Invested Capital (ROIC)---72.19%-53.65%-50.18%-51.52%-34.78%-43.45%-26.94%-26.94%
Gross Margin-123.09%-26.59%12.8%31.85%39.08%41.38%36.61%42.61%50.72%52.07%
Net Margin-550.85%-280.16%-197.98%-155.31%-114.94%-107.02%-83.48%-66.69%-20.63%-19.85%
Debt / Equity--0.05x0.11x0.11x0.12x0.15x0.18x0.29x0.29x
Interest Coverage-64.23x-53.07x-81.98x-176.32x-418.69x-2852.43x-40692.20x-7177.14x--
FCF Conversion0.86x0.93x0.82x1.02x0.74x0.57x0.70x0.31x0.61x1.17x
Revenue Growth374.53%136.16%113.89%65.67%46.87%53.83%20.41%27.69%20.32%17.77%

TWST SEC Filings & Documents

Twist Bioscience Corporation (TWST) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 4, 2026·SEC

Material company update

Feb 17, 2026·SEC

Material company update

Feb 6, 2026·SEC

10-K Annual Reports

1
FY 2025

Nov 17, 2025·SEC

10-Q Quarterly Reports

4
FY 2026

May 4, 2026·SEC

FY 2026

Feb 2, 2026·SEC

FY 2025

Aug 4, 2025·SEC

TWST Frequently Asked Questions

Twist Bioscience Corporation (TWST) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Twist Bioscience Corporation (TWST) reported $409.5M in revenue for fiscal year 2025. This represents a 17947% increase from $2.3M in 2016.

Twist Bioscience Corporation (TWST) grew revenue by 20.3% over the past year. This is strong growth.

Twist Bioscience Corporation (TWST) reported a net loss of $81.3M for fiscal year 2025.

Dividend & Returns

Twist Bioscience Corporation (TWST) has a return on equity (ROE) of -16.4%. Negative ROE indicates the company is unprofitable.

Twist Bioscience Corporation (TWST) had negative free cash flow of $95.1M in fiscal year 2025, likely due to heavy capital investments.

Explore More TWST

Twist Bioscience Corporation (TWST) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

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Dividend History

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Earnings History

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Price History

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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