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TWSTTwist Bioscience Corporation
$164.60$9.9B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
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TWST logo

Twist Bioscience Corporation

TWST
NASDAQ · Diagnostics & Research
$164.60
At close - Sep 22, 4:00 PM EDT - USD
Market Cap$10.25B
P/E-126.6x
52W High$170.66
Volume2.31M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Revenue Growth Persists Amid Persistent Cash Burn

Twist Bioscience continues to demonstrate robust top-line momentum, with revenue growing 23.2% year-over-year to $118.4M in 2026Q3, marking the fourteenth consecutive quarter of growth. However, the company remains deeply unprofitable, with an operating margin...

GrowthAccelerating
ProfitabilityWeak
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

TWST price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-389% Peers

P/E is 389% below peer median

03

Market leadership

RS 98 · Leader

High momentum (Outperforming 98% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystConfirmed earnings · Nov 13
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue growth accelerated to 23.2% year-over-year in 2026Q3, but gross margin plateaued at 52.8% and operating margin remained deeply negative at -30.6%, with SG&A consuming 68% of revenue.

Analyst Consensus-26.6% target
Buy(14 analysts)
11 Buy2 Hold1 Sell

The Bull Case

Upside Catalysts

Innovative DNA synthesis technology

Twist Bioscience's silicon-based DNA synthesis enables high-precision, high-throughput manufacturing, giving it a competitive edge in synthetic biology.

Diverse market applications

The company's platform supports research across medicine, agriculture, industrial biology, and biopharma, broadening its revenue potential.

Bullish investor sentiment

Multiple bullish theses highlight Twist Bioscience's growth potential, with analysts summarizing positive outlooks on its stock performance.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 9/23/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
TWST+408.18%
S&P 500 (^GSPC)+13.20%
1-Year Return
TWST+491.87%
S&P 500 (^GSPC)+15.98%
3-Year Return
TWST+709.24%
S&P 500 (^GSPC)+67.91%
5-Year Return
TWST+36.12%
S&P 500 (^GSPC)+74.10%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
-121.9x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-121.9x
N/A
N/A
EV/EBITDA
N/A
N/A
N/A
Price/FCF
N/A
N/A
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$3.70-97.8%
Base (Fair)$81.85-51.0%
Bull$5.28-96.8%
$3.70 Bear$81.85 Base$5.28 Bull
Current Market Price: $164.60
Trades at a 101.1% premium to Base DCF ($81.85)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue
$377M+20.3% YoY
Net income
-$78M+62.8% YoY
Free cash flow
-$76M-9.3% YoY
Operating margin
-36.2%+34.4 pts YoY
ROIC (TTM)-26.9%
Avg ROIC 5Y-
ROE (TTM)-16.4%
Piotroski Score4 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
Revenue Beat Rate9/12 (75%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 3, 2026
-$0.56-10.6%
vs -$0.51
$118M+3.4%
vs $115M
Q2 2026
May 4, 2026
-$0.71-44.9%
vs -$0.49
$111M+2.9%
vs $108M
Q1 2026
Feb 2, 2026
-$0.50-4.2%
vs -$0.48
$104M+1.8%
vs $102M
Q4 2025
Nov 14, 2025
-$0.45+10.0%
vs -$0.50
$99M+1.7%
vs $97M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Benzinga·Sep 16, 2026
Beyond Hype: Twist Bioscience Secures Data Pipeline Role In Eli Lilly TuneLab Ecosystem

Twist Bioscience Corporation (NASDAQ:TWST) on Wednesday announced an agreement with Lilly TuneLab, a collaborative AI/ML drug discovery platform created by Eli Lilly and Co. (NYSE:LLY).

GuruFocus·Sep 16, 2026
Twist Bioscience Joins Lilly TuneLab to Advance Antibody Drug Discovery

[url="]Twist Bioscience Corporation[/url] (NASDAQ: TWST), a mid-cap growth and value biotech company, today announced an agreement with Lilly TuneLab, a collabo

ETF Trends·Sep 9, 2026
AI & Robotics in 2026: 16 Recent Developments for Investors

If AI and robotics suddenly feel like they are moving faster, August gave investors plenty of evidence that the pace really is accelerating. We saw longer-running agents, faster and cheaper inference, AI systems reaching into laboratories and physical equipment, robots learning from fewer demonstrations, and new capital and infrastructure forming around commercial deployment.

Business Wire·Sep 9, 2026
Twist Bioscience to Present at Baird 2026 Global Healthcare Conference

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Twist Bioscience Corporation (NASDAQ: TWST), a mid-cap growth and value biotech company, today announced that Emily M. Leproust, Ph.D., CEO and co-founder of Twist Bioscience, and Adam Laponis, CFO of Twist Bioscience, will participate in a fireside chat at the Baird 2026 Global Healthcare Conference on Tuesday, September 15, 2026 at 1:25 pm Eastern Time in New York City. The fireside chat will be webcast live and can be accessed by visiting the “In.

Filtered for Twist Bioscience CorporationMore Headlines
04

Compare before deciding

Benchmark TWST against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Twist Bioscience Corporation (TWST)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TWST logoTWSTTwist Bioscience CorporationCurrent
$164.60$10.25B-126.6220.32%-20.63%-16.43%—
ILMN logoILMNIllumina, Inc.
$247.46$37.44B45.41-0.78%18.36%31.08%—
PACB logoPACBPacific Biosciences of California, Inc.
$1.47$456.58M-0.813.89%-82.49%-4961.74%—
BEAM logoBEAMBeam Therapeutics Inc.
$25.93$2.67B-32.01120.01%-54.75%-7.7%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$12.69$1.42B-3.3316.92%-672.16%-57.79%—
GH logoGHGuardant Health, Inc.
$177.16$23.49B-53.3632.88%-38.33%——

Compare TWST vs Peers

Twist Bioscience Corporation (TWST) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ILMN

Most directly comparable listed peer for TWST.

Scale Benchmark

vs TMO

Larger-name benchmark to compare TWST against a more recognizable public peer.

Peer Set

Compare Top 5

vs ILMN, PACB, BEAM, NTLA

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

TWST SEC Filings & Documents

Twist Bioscience Corporation (TWST) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 5, 2026·SEC

Material company update

Aug 3, 2026·SEC

Material company update

May 4, 2026·SEC

10-K Annual Reports

1
FY 2025

Nov 17, 2025·SEC

10-Q Quarterly Reports

5
FY 2026

Aug 3, 2026·SEC

FY 2026

May 4, 2026·SEC

FY 2026

Feb 2, 2026·SEC

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TWST Frequently Asked Questions

Twist Bioscience Corporation (TWST) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Twist Bioscience Corporation's revenue?

Twist Bioscience Corporation (TWST) reported $431.8M in revenue for fiscal year 2025. This represents a 18930% increase from $2.3M in 2016.

How fast is Twist Bioscience Corporation growing?

Twist Bioscience Corporation (TWST) grew revenue by 20.3% over the past year. This is strong growth.

Is TWST profitable?

Twist Bioscience Corporation (TWST) reported a net loss of $136.7M for fiscal year 2025.

Dividend & Returns
What is TWST's return on equity?

Twist Bioscience Corporation (TWST) has a return on equity (ROE) of -16.4%. Negative ROE indicates the company is unprofitable.

What is Twist Bioscience Corporation's free cash flow?

Twist Bioscience Corporation (TWST) had negative free cash flow of $93.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TWST back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →