TWST trades 29.3% above Wall Street's consensus target of $116.33.
Last 12 months price action with 12-month analyst target path
The base valuation assumes TWST achieves its forward estimates and maintains a stable P/E multiple of historical averagesx. This scenario reflects the blended consensus of 14 Wall Street analysts, balancing both positive catalysts and macroeconomic headwinds over the next 12 months.
As of September 24, 2026, Twist Bioscience Corporation (TWST) has a Wall Street consensus price target of $116.33, based on estimates from 14 covering analysts. With the stock currently trading at $164.60, this represents a potential downside of -29.3%. The company has a market capitalization of $10.25B.
Analyst price targets range from a low of $89.00 to a high of $160.00, representing a 61% spread in expectations. The median target of $115.00 aligns closely with the consensus average. The wide target spread reflects significant disagreement on fair value.
The current analyst consensus rating is Buy, with 11 analysts rating the stock as a Buy or Strong Buy,2 rating it Hold, and 1 rating it Sell or Strong Sell. This overwhelmingly bullish sentiment suggests analysts see significant catalysts for upside ahead.
From a valuation perspective, TWST trades at a trailing P/E of -126.6x. Analysts expect EPS to grow +1.5% over the next year.
| Company | Market Cap | Price | Target | Upside Potential | Rating | Fwd P/E | Analysts |
|---|---|---|---|---|---|---|---|
 ILMNIllumina, Inc. | $37.4B | $247.46 | $210.67 | -14.9% | Buy | 46.2x | 50 |
 PACBPacific Biosciences of California, Inc. | $457M | $1.47 | $1.18 | -19.7% | Buy | — | 18 |
 BEAMBeam Therapeutics Inc. | $2.7B | $25.93 | $59.50 | +129.5% | Buy | — | 27 |
 NTLAIntellia Therapeutics, Inc. | $1.4B | $12.69 | $23.00 | +81.2% | Buy | — | 39 |
 GHGuardant Health, Inc. | $23.5B | $177.16 | $199.40 | +12.6% | Buy | — | 31 |
 EXASExact Sciences Corporation | $20.0B | $104.91 | $92.95 | -11.4% | Buy | 582.8x | 41 |
 CDNACareDx, Inc | $2.9B | $56.49 | $58.75 | +4.0% | Buy | 46.9x | 13 |
 NTRANatera, Inc. | $56.0B | $390.90 | $335.07 | -14.3% | Buy | — | 28 |
 FLGTFulgent Genetics, Inc. | $615M | $21.65 | $19.00 | -12.2% | Buy | — | 9 |
 TMOThermo Fisher Scientific Inc. | $244.7B | $658.52 | $623.36 | -5.3% | Buy | 26.2x | 43 |
Quick answers to the most common questions about buying TWST stock.
TWST's consensus price target is $116.33, -29.3% below the current price of $164.6. The 14 analysts tracking TWST see downside risk at present valuations.
TWST has a consensus rating of "Buy" based on 14 Wall Street analysts. The rating breakdown is predominantly bullish, with 11 Buy/Strong Buy ratings. The consensus 12-month price target of $116.33 implies -29.3% downside from current levels.
TWST's current price is $164.6 with a consensus target of $116.33 (-29.3% implied move). Analyst estimates suggest the stock is overvalued at current levels.
The most bullish Wall Street analyst has a price target of $160 for TWST, while the most conservative target is $89. The consensus of $116.33 represents the median expectation. These targets typically reflect 12-month expectations.
TWST is moderately covered, with 14 analysts providing price targets and ratings. Of these, 0 have Strong Buy ratings, 11 have Buy ratings, 2 recommend Hold, and 1 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.
The 12-month TWST stock forecast based on 14 Wall Street analysts shows a consensus price target of $116.33, with estimates ranging from $89 (bear case) to $160 (bull case). The median consensus rating is "Buy".
Analysts are cautious on TWST, with 1 Sell ratings and a price target of $116.33 (-29.3% from current price). The "Buy" consensus suggests careful evaluation before buying. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.
TWST analyst price targets range from $89 to $160, a 61% wide spread indicating significant analyst disagreement. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $116.33 consensus represents the middle ground.
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