Xencor, Inc. (XNCR) P/E Ratio History
Historical price-to-earnings valuation from 2016 to 2022
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XNCR Valuation Context
How does the current P/E compare to historical and market benchmarks?
P/E Ratio Analysis
As of May 8, 2026, Xencor, Inc. (XNCR) trades at a price-to-earnings ratio of -9.9x, with a stock price of $12.31 and trailing twelve-month earnings per share of $-2.29.
The current P/E is 118% below its 5-year average of 54.0x. Over the past five years, XNCR's P/E has ranged from a low of 15.0x to a high of 114.0x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 22.3x, XNCR trades at a 144% discount to its sector peers. The sector includes 241 companies with P/E ratios ranging from 0.0x to 177.5x.
Relative to the broader market, XNCR trades at a notable discount to the S&P 500 median P/E of 25.1x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our XNCR DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
XNCR P/E vs Peers
P/E ratio compared to closely matched public peers
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $6B | 24.8 | - | -34% | |
| $358B | 85.5 | - | -1% | |
| $74B | 17.1 | 2.70Best | +8% | |
| $39B | 127.0 | - | +207% | |
| $20B | 15.3Lowest | - | +4173%Best |
Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.
XNCR Historical P/E Data (2016–2022)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Date | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2022 Q3 | Fri Sep 30 2022 00:00:00 GM | $25.98 | $0.38 | 68.4x | +27% |
| FY2022 Q2 | $27.37 | $0.24 | 114.0x | +111% | |
| FY2022 Q1 | $26.68 | $1.78 | 15.0x | -72% | |
| FY2021 Q4 | Fri Dec 31 2021 00:00:00 GM | $40.12 | $1.35 | 29.8x | -45% |
| FY2021 Q2 | Wed Jun 30 2021 00:00:00 GM | $34.49 | $0.37 | 94.0x | +74% |
| FY2019 Q4 | $34.39 | $0.45 | 76.4x | +41% | |
| FY2019 Q3 | Mon Sep 30 2019 00:00:00 GM | $33.73 | $0.60 | 56.2x | +4% |
| FY2019 Q2 | Sun Jun 30 2019 00:00:00 GM | $40.93 | $0.83 | 49.3x | -9% |
| FY2019 Q1 | Sun Mar 31 2019 00:00:00 GM | $31.06 | $0.65 | 47.8x | -12% |
| FY2017 Q1 | Fri Mar 31 2017 00:00:00 GM | $23.92 | $0.41 | 58.3x | +8% |
| FY2016 Q4 | Sat Dec 31 2016 00:00:00 GM | $26.32 | $0.56 | 47.0x | -13% |
| FY2016 Q3 | Fri Sep 30 2016 00:00:00 GM | $24.49 | $0.96 | 25.5x | -53% |
Average P/E for displayed period: 54.0x
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Start ComparisonXNCR — Frequently Asked Questions
Quick answers to the most common questions about buying XNCR stock.
Is XNCR stock overvalued or undervalued?
XNCR trades at -9.9x P/E, below its 5-year average of 54.0x. At the N/A percentile of historical range, the stock is priced at a discount to its own history.
How does XNCR's valuation compare to peers?
Xencor, Inc. P/E of -9.9x compares to sector median of 22.3x. The discount suggests lower growth expectations or higher risk.
What is XNCR's PEG ratio?
XNCR PEG ratio is N/A. Above 2.0 indicates premium valuation relative to growth rate. Historical P/E data spans 2016-2022.