Xencor, Inc. (XNCR) P/E Ratio History
Historical price-to-earnings valuation from 2016 to 2022
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Valuation Context
How does the current P/E compare to historical and market benchmarks?
P/E Ratio Analysis
As of March 2, 2026, Xencor, Inc. (XNCR) trades at a price-to-earnings ratio of -10.3x, with a stock price of $12.77 and trailing twelve-month earnings per share of $-1.24.
The current P/E is 119% below its 5-year average of 54.0x. Over the past five years, XNCR's P/E has ranged from a low of 15.0x to a high of 114.0x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 23.7x, XNCR trades at a 143% discount to its sector peers. The sector includes 224 companies with P/E ratios ranging from 0.0x to 184.4x.
Relative to the broader market, XNCR trades at a notable discount to the S&P 500 median P/E of 26.2x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our XNCR DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
Peer Comparison
P/E metrics vs. Drug Discovery and Antibody Platforms peers
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
REGNRegeneron Pharmaceuticals, Inc. | $108B | 18.8 | 2.98Best | +8% |
CTMXCytomX Therapeutics, Inc. | $430M | 14.1 | - | - |
PRTCPureTech Health plc | $405M | 8.4Lowest | - | +183%Best |
Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.
Historical P/E Data
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Date | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2022 Q3 | Fri Sep 30 2022 00:00:00 GM | $25.98 | $0.38 | 68.4x | +27% |
| FY2022 Q2 | $27.37 | $0.24 | 114.0x | +111% | |
| FY2022 Q1 | $26.68 | $1.78 | 15.0x | -72% | |
| FY2021 Q4 | Fri Dec 31 2021 00:00:00 GM | $40.12 | $1.35 | 29.8x | -45% |
| FY2021 Q2 | Wed Jun 30 2021 00:00:00 GM | $34.49 | $0.37 | 94.0x | +74% |
| FY2019 Q4 | $34.39 | $0.45 | 76.4x | +41% | |
| FY2019 Q3 | Mon Sep 30 2019 00:00:00 GM | $33.73 | $0.60 | 56.2x | +4% |
| FY2019 Q2 | Sun Jun 30 2019 00:00:00 GM | $40.93 | $0.83 | 49.3x | -9% |
| FY2019 Q1 | Sun Mar 31 2019 00:00:00 GM | $31.06 | $0.65 | 47.8x | -12% |
| FY2017 Q1 | Fri Mar 31 2017 00:00:00 GM | $23.92 | $0.41 | 58.3x | +8% |
| FY2016 Q4 | Sat Dec 31 2016 00:00:00 GM | $26.32 | $0.56 | 47.0x | -13% |
| FY2016 Q3 | Fri Sep 30 2016 00:00:00 GM | $24.49 | $0.96 | 25.5x | -53% |
Average P/E for displayed period: 54.0x
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Start ComparisonFrequently Asked Questions
Is XNCR stock overvalued or undervalued?
XNCR trades at -10.3x P/E, below its 5-year average of 54.0x. At the N/A percentile of historical range, the stock is priced at a discount to its own history.
How does XNCR's valuation compare to peers?
Xencor, Inc. P/E of -10.3x compares to sector median of 23.7x. The discount suggests lower growth expectations or higher risk.
What is XNCR's PEG ratio?
XNCR PEG ratio is N/A. Above 2.0 indicates premium valuation relative to growth rate. Historical P/E data spans 2016-2022.