Xencor, Inc. (XNCR) Revenue History
Annual and quarterly revenue from 2014 to 2025
Compound Annual Growth Rate (CAGR)
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XNCR Revenue Growth
Revenue Breakdown (FY 2025)
XNCR's revenue distribution by segment and geography for fiscal year 2025
By Product/Segment
By Geography
XNCR Revenue Analysis (2014–2025)
As of May 7, 2026, Xencor, Inc. (XNCR) generated trailing twelve-month (TTM) revenue of $92.8 million, reflecting significant decline in growth of -100.0% year-over-year. The most recent quarter (Q1 2026) recorded $0 in revenue, down 100.0% sequentially.
Looking at the longer-term picture, XNCR's 5-year compound annual growth rate (CAGR) stands at +0.5%, indicating moderate growth over time. The company achieved its highest annual revenue of $275.1 million in 2021.
Revenue diversification analysis shows XNCR's business is primarily driven by Royalty (64%), and Milestone (36%). With over half of revenue concentrated in Royalty, the company maintains significant focus in this area while developing other growth vectors.
When compared to Healthcare sector peers including RCUS (+67.4% YoY), MGNX (+0.8% YoY), and ALKS (+3.2% YoY), XNCR has underperformed the peer group in terms of revenue growth. Compare XNCR vs RCUS →
XNCR Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| XNCRCurrent | $93M | -100.0% | +0.5% | -141.4% | |
 RCUS | $247M | +67.4% | +25.9% | -156.3% | |
 MGNX | $150M | +0.8% | +8.9% | -48.7% | |
 ALKS | $1.5B | +3.2% | +7.3% | 17.2% | |
 ZYME | $106M | +38.9% | +22.2% | -87.3% |
XNCR Historical Revenue Data (2014–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $125.6M | +13.7% | $115.1M | 91.6% | $-177,502,000 | -141.4% |
| 2024 | $110.5M | -36.7% | $110.5M | 100.0% | $-178,408,000 | -161.5% |
| 2023 | $174.6M | +6.1% | $174.6M | 100.0% | $-132,362,000 | -75.8% |
| 2022 | $164.6M | -40.2% | $164.6M | 100.0% | $-82,473,000 | -50.1% |
| 2021 | $275.1M | +124.2% | $275.1M | 100.0% | $43.8M | 15.9% |
| 2020 | $122.7M | -21.7% | $-47,108,000 | -38.4% | $-76,797,000 | -62.6% |
| 2019 | $156.7M | +285.9% | $38.1M | 24.3% | $13.8M | 8.8% |
| 2018 | $40.6M | +13.7% | $-56,898,000 | -140.1% | $-79,370,000 | -195.5% |
| 2017 | $35.7M | -59.2% | $-36,061,000 | -101.0% | $-53,562,000 | -150.0% |
| 2016 | $87.5M | +215.3% | $35.6M | 40.7% | $22.5M | 25.8% |
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Start ComparisonXNCR — Frequently Asked Questions
Quick answers to the most common questions about buying XNCR stock.
Is XNCR's revenue growth accelerating or slowing?
XNCR revenue declined -100.0% year-over-year, contrasting with the 5-year CAGR of +0.5%. TTM revenue fell to $93M. This reverses the prior growth trend.
What is XNCR's long-term revenue growth rate?
Xencor, Inc.'s 5-year revenue CAGR of +0.5% reflects the variable expansion pattern. Current YoY growth of -100.0% is below this long-term average.
How is XNCR's revenue distributed by segment?
XNCR reports revenue by product line and geographic region. Annual and quarterly breakdowns from 2014-2025 are available for download. Segment mix reveals concentration and diversification trends.