The firm exhibits a chronic cash burn, with quarterly free cash flow outflows frequently exceeding $700,000, as highlighted by the 2024Q4 OCF/NI ratio of -7.23.
| Cash from Operations | -2.62M | -2.82M | -5.04M | -6.58M | -8.96M | -4.8M | -728.4K | -249.58K | -1.56M | 72.5K | -107.78K | -128.57K | -85.36K |
| Operating CF Margin % | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Operating CF Growth % | 52.45% | 44.1% | 23.45% | 26.56% | -86.7% | -559.12% | -191.85% | 83.95% | -2245.2% | 167.27% | 16.17% | -50.62% | - |
| Net Income | -2.75M | -2.7M | -4.54M | -2.16M | -7.72M | -1.58M | -1.01M | -481.96K | -3.78M | -377.1K | -321.48K | -151.01K | -29.51K |
| Depreciation & Amortization | 111.74K | 114.08K | 160.66K | 105.18K | 58.15K | 14.27K | 20.44K | 15.23K | 14.18K | 13.34K | 0 | 0 | 0 |
| Stock-Based Compensation | 6.95K | 0 | 0 | 120.98K | 487.94K | 576.01K | 293.44K | 26.32K | 275.09K | 92.67K | 219 | 35.65K | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 34.06K | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -332.81K | -570.57K | -821.11K | -3.62M | -2.58M | -2.73M | -397.09K | -211.31K | 2.58M | 106.86K | 208.09K | 1 | 0 |
| Working Capital Changes | 349.15K | 342.1K | 160K | -1.03M | 787.32K | -1.08M | 362.21K | 368.08K | -651.93K | 236.72K | 5.39K | -13.21K | -55.85K |
| Change in Receivables | -48.71K | -63.63K | 59.01K | 21 | -43.61K | -29.17K | 0 | 14.79K | -20.06K | 0 | 0 | 6.09K | 1.58K |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | -303.8K | -300.12K | -53.32K | -46.36K | -45.7K | -31.81K | -14.35K | -7.04K | -154.81K | -12.48K | -24.56K | -39.11K | -30.17K |
| Capital Expenditures | -55.81K | -56.19K | -53.32K | -6 | -44.22K | -31.22K | -11.25K | -5.39K | 0 | -1.17K | -3.79K | -39.11K | -24.11K |
| CapEx % of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -280.95K | -167 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -248K | -243.93K | 0 | -46.36K | -1.48K | -585 | -3.1K | -1.65K | 126.15K | -11.15K | -20.77K | 0 | -6.06K |
| Cash from Financing | 1.27M | 1.45M | 3.81M | -487.3K | 4.71M | 19.37M | 670.82K | 42.27K | 1.4M | 106.32K | 115K | 194.14K | 109.19K |
| Debt Issued (Net) | -23.26K | 0 | -69.72K | -66.09K | -20.41K | 0 | 0 | 0 | 0 | 79.52K | 0 | 0 | 0 |
| Equity Issued (Net) | 1.36M | 1.54M | 3.9M | 0 | 5M | 18.07M | 705.79K | 70K | 1.44M | 0 | 272.92K | 315.84K | 83.52K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -61.11K | -91.14K | -25.8K | -421.21K | -269.49K | 1.3M | -34.97K | -27.73K | -36.07K | 26.8K | -157.91K | -121.7K | 25.67K |
| Net Change in Cash | -1.66M | -1.73M | -974.02K | -6.99M | -4.44M | 14.74M | 112.66K | -201.41K | 198.08K | 35.92K | 113.09K | 26.45K | -359 |
| Free Cash Flow | -2.15M | -2.82M | -5.04M | -6.63M | -9.01M | -4.83M | -742.75K | -196.45K | -1.6M | 62.58K | -132.34K | -167.69K | -109.48K |
| FCF Margin % | - | - | - | - | - | - | - | - | - | - | - | - | - |
| FCF Growth % | 29.72% | 44.1% | 23.98% | 26.41% | -86.42% | -550.67% | -278.09% | 87.69% | -2651.19% | 147.28% | 21.08% | -53.17% | - |
| FCF per Share | -1.54 | -14.88 | -43.77 | -83.63 | -152.20 | -110.43 | -25.08 | -7.85 | -63.77 | 7.36 | -18.55 | -20.73 | -33.95 |
| FCF Conversion (FCF/Net Income) | 0.78x | 1.06x | 1.11x | 2.30x | 1.28x | 2.91x | 0.57x | 0.40x | 0.41x | -0.15x | 0.26x | 0.46x | 2.31x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imminent liquidity and dilution
As reported in financial statements, the persistent divergence between net income and operating cash flow, highlighted by a 2024Q4 OCF/NI ratio of -7.23, indicates that accounting adjustments frequently obscure the underlying reality of the company's cash-intensive drug development activities and ongoing operational losses.
The significant gap between net income and operating cash flow suggests that non-cash items, likely related to derivative warrant liabilities, are creating artificial volatility in reported earnings. Investors should monitor this disconnect, as it implies that bottom-line figures provide little insight into the actual cash resources available to fund clinical trials.
Based on recent SEC filings, XORTX consistently reports negative free cash flow, with quarterly outflows frequently exceeding $700,000, underscoring the company's reliance on external financing to sustain its R&D pipeline in the absence of any commercial revenue streams or self-sustaining operational cash generation.
The lack of positive free cash flow is a structural characteristic of the firm's current pre-revenue stage. This trajectory suggests that the company remains entirely dependent on capital markets, leaving it highly sensitive to shifts in investor sentiment regarding the clinical viability of its xanthine oxidase inhibitors.
According to historical data, working capital changes have been highly erratic, with fluctuations ranging from a $659,200 inflow in 2024Q2 to a $412,200 outflow in 2023Q4, suggesting that these movements are driven more by financing timing than by operational efficiency or inventory management.
The erratic nature of these working capital shifts warrants further investigation, as they appear to be a byproduct of the company's efforts to manage its limited liquidity. Such volatility may indicate that the firm is aggressively managing payables to preserve cash, which could potentially impact vendor relationships or clinical trial timelines.
As reported in financial statements, the company's cash position of $862,940 is dangerously low, and the cash flow statement fails to fully capture the potential impact of future financing requirements or the dilutive nature of the capital needed to maintain the XRx-008 clinical program.
The cash flow statement provides a clear view of the burn rate but obscures the looming necessity for dilutive equity raises. Investors should be wary that the current cash balance may not be sufficient to reach the next major clinical inflection point, potentially forcing management into unfavorable financing terms.
Quick answers to the most common questions about buying XRTX stock.
XORTX Therapeutics Inc. (XRTX) generated $-2.8M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
XORTX Therapeutics Inc. (XRTX) reported negative free cash flow of $2.8M in 2025, indicating capital requirements exceeded cash from operations.
XORTX Therapeutics Inc. (XRTX) spent $0.1M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.