XORTX Therapeutics Inc. (XRTX) P/E Ratio History
Deep ValueTrading at -0.2x · 0th percentile of 5-year range · Significant discount to historical valuation · Data 2022–2022
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P/E Ratio Analysis
As of June 30, 2026, XORTX Therapeutics Inc. (XRTX) trades at a price-to-earnings ratio of -0.2x, with a stock price of $2.20 and trailing twelve-month earnings per share of $-1.98.
The current P/E is 118% below its 5-year average of 0.9x. Over the past five years, XRTX's P/E has ranged from a low of 0.9x to a high of 0.9x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 22.9x, XRTX trades at a 101% discount to its sector peers. The sector includes 231 companies with P/E ratios ranging from 0.0x to 191.6x.
Relative to the broader market, XRTX trades at a notable discount to the S&P 500 median P/E of 25.1x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our XRTX DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
XRTX Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
XRTX P/E vs Peers
Metabolic and Obesity Therapies peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $4B | 18.7 | 1.00 | +28% | |
| $11B | 55.3 | - | +128% | |
| $9B | 30.1 | 1.31 | -25% | |
| $2B | 7.0Lowest | 0.68Best | +817%Best | |
| $7B | 10.5 | - | +264% |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
XRTX Historical P/E Data (2022–2022)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Period End | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2022 Q3 | Sep 30 2022 | $54.45 | $62.00 | 0.9x | +0% |
Average P/E for displayed period: 0.9x
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
4+ years return with dividends reinvested.
DCA Calculator
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Peer Comparison
Compare growth, multiples, and margins vs sector.
XRTX — Frequently Asked Questions
Quick answers to the most common questions about buying XRTX stock.
What is XRTX's P/E ratio?
XORTX Therapeutics Inc. (XRTX) trailing twelve-month P/E ratio is -0.2x, based on TTM diluted EPS of $-1.98. The 5-year average P/E is 0.9x and the historical range spans 0.9x to 0.9x.
Is XRTX stock overvalued or undervalued?
XRTX trades at -0.2x P/E, below its 5-year average of 0.9x. At the 0th percentile of its historical range (0.9x–0.9x), the stock is priced at a discount to its own history.
Is XRTX stock expensive?
No, XRTX is not expensive on a historical basis. The current P/E of -0.2x is below the 5-year average of 0.9x and sits at the 0th percentile of its valuation range.
What is XRTX's historical P/E range?
Over the past 5 years, XRTX's P/E ratio has ranged from 0.9x to 0.9x, with a median of 0.9x and an average of 0.9x. The current P/E of -0.2x places the stock at the 0th percentile of this range. Full historical data spans 2022–2022.
How does XRTX's P/E compare to the S&P 500?
XRTX trades at -0.2x P/E versus the S&P 500 median of 25.1x. The 101% discount to the market suggests lower growth expectations or perceived higher risk.
How does XRTX's valuation compare to Healthcare peers?
XORTX Therapeutics Inc. P/E of -0.2x compares to the Healthcare sector median of 22.9x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.
What is XRTX's PEG ratio?
XRTX PEG ratio is N/A, based on a P/E of -0.2x and EPS growth of 64.1%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is XRTX's earnings yield?
XRTX earnings yield is N/A, the inverse of its -0.2x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.