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Castle Biosciences, Inc. (CSTL) Total Return Calculator with Dividends Reinvested

Castle Biosciences, Inc.

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The total return for Castle Biosciences, Inc. (CSTL) stock is +48.92% over the past 12 months. So far it's down 35.78% this year. The 5-year total return is -55.99%, meaning $10,000 invested in CSTL stock 5 years ago would be worth $4,401 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in CSTL 1 year ago, it would be worth $14,892 today — you'd have gained $4,892.

With Dividends Reinvested$14,892+48.92%

Price Only (No DRIP)$14,892+48.92%

Period2025-05-06 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in CSTL

1Y$14,892+$4,892 (+48.9%)48.9% CAGR

3Y$10,932+$932 (+9.3%)3.0% CAGR

5Y$4,401-$5,599 (-56.0%)-15.1% CAGR

10Y$11,565+$1,565 (+15.7%)1.5% CAGR

15Y$11,565+$1,565 (+15.7%)1.0% CAGR

20Y$11,565+$1,565 (+15.7%)0.7% CAGR

30Y$11,566+$1,566 (+15.7%)0.5% CAGR

Castle Biosciences, Inc. did not pay dividends during this period. Total return = price return.

Loading CSTL total return...

As of 2026-05-06

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-35.78%	—	-35.78%	—	$6,422
1Y	+48.92%	48.92%	+48.92%	—	$14,892
3Y	+9.32%	3.01%	+9.32%	—	$10,932
5Y	-55.99%	-15.14%	-55.99%	—	$4,401
10Y	+15.65%	1.47%	+15.65%	—	$11,565
15Y	+15.65%	0.97%	+15.65%	—	$11,565
20Y	+15.65%	0.73%	+15.65%	—	$11,565
30Y	+15.66%	0.49%	+15.66%	—	$11,566

Risk & Highlights

Best Year+98.55%2020

Worst Year-48.41%2022

Max Drawdown-46.26%2026-01-26 → 2026-04-10

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-23.27%	-23.27%	—	+0.41%	-23.7pp
2025	+38.73%	+38.73%	—	+16.64%	+22.1pp
2024	+21.36%	+21.36%	—	+24.00%	-2.6pp
2023	-5.27%	-5.27%	—	+24.81%	-30.1pp
2022	-48.41%	-48.41%	—	-19.95%	-28.5pp

CSTL outperformed the S&P 500 by 17.59pp over the past year (+48.92% vs +31.32%).

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CSTL Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
CSTLCastle Biosciences, Inc.	$750M	+0.1%	-35.8%	+48.9%	—	+9.3%	-56.0%	+15.7%
NTRANatera, Inc.	$29.6B	+5.0%	-6.0%	+38.3%	—	+305.1%	+123.3%	+2147.5%
EXASExact Sciences Corporation	$20.0B	—	+3.1%	+94.3%	—	+53.0%	-2.9%	+1672.1%
VCYTVeracyte, Inc.	$3.3B	+27.4%	-2.8%	+34.8%	—	+82.0%	-6.0%	+669.9%
ARDXArdelyx, Inc.	$1.7B	+18.9%	+15.4%	+79.7%	—	+69.5%	+327.7%	+290.1%
FLGTFulgent Genetics, Inc.	$444M	-9.1%	-41.7%	-20.7%	—	-54.9%	-79.6%	+62.5%
GHGuardant Health, Inc.	$11.5B	+2.9%	-9.3%	+120.0%	—	+292.1%	-31.5%	+186.5%
ILMNIllumina, Inc.	$21.7B	+11.6%	+6.1%	+91.3%	—	-25.0%	-61.1%	+4.3%
CDNACareDx, Inc	$1.1B	+17.5%	+9.4%	+47.7%	—	+155.1%	-71.2%	+380.3%
PACBPacific Biosciences of California, Inc.	$516M	+20.4%	-7.1%	+55.5%	—	-86.0%	-93.0%	-80.3%
LHLabcorp Holdings Inc.	$21.1B	-6.4%	+2.4%	+6.5%	+1.2pp	+38.8%	+12.2%	+150.9%

Compare:CSTL vs NTRA CSTL vs EXAS CSTL vs VCYT CSTL vs NTRA vs EXAS

About CSTL Dividend Returns

Castle Biosciences, Inc. (CSTL) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of CSTL over the past year?

Castle Biosciences, Inc. (CSTL) delivered a return of 48.92% over the past year. Since CSTL does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in CSTL be worth today?

A $10,000 investment in Castle Biosciences, Inc. one year ago would be worth $14,892 today, representing a gain of $4,892.

Q3Does CSTL pay dividends?

Castle Biosciences, Inc. (CSTL) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For CSTL, the total return equals the price-only return.

Q4Did CSTL beat the S&P 500?

Yes, Castle Biosciences, Inc. (CSTL) outperformed the S&P 500 by 17.59 percentage points over the past year. CSTL delivered a total return of 48.92%, compared to the S&P 500's 31.32%. This 17.59pp alpha means investors in CSTL earned more than a passive S&P 500 index fund.

Q5What is CSTL's worst drawdown?

Castle Biosciences, Inc. (CSTL) experienced a maximum drawdown of -46.26% over the past year, declining from its peak on 2026-01-26 to its trough on 2026-04-10. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is CSTL's long-term total return over 10, 20, or 30 years?

Here are Castle Biosciences, Inc. (CSTL)'s long-term returns with dividends reinvested. Over 10 years, the total return is 15.7% (1.5% CAGR) — $10,000 would have grown to $11,565. Over 20 years: 15.7% total return (0.7% CAGR) — $10,000 → $11,565. Over 30 years: 15.7% total return (0.5% CAGR) — $10,000 → $11,566. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was CSTL's best and worst year?

Castle Biosciences, Inc.'s best calendar year was 2020 with a total return of 98.6%. Its worst year was 2022 with a total return of -48.4%. This range shows the volatility investors should expect — the difference between the best and worst year is 147.0 percentage points.