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CSTL logoCastle Biosciences, Inc. (CSTL) Earnings History

Annual and quarterly earnings data from 2017 to 2025

TTM Net Income
-$13M
Net Loss
TTM EPS
$-0.43
Diluted
YoY EPS Growth
-233.9%
Declining
Net Margin
-7.0%
Profitability
Operating Margin-12.4%
Gross Margin68.7%
ROE-5.2%
ROA-4.4%
Highest Annual Net Income$18M (2024)
Highest Quarterly EPS$0.36 (Q4 2018)
Consecutive Profitable Years0 years
Q1 2026
Net Income-$15M
EPS$-0.49
QoQ Growth-522.7%Declining

Loading earnings history...

CSTL EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

CSTL Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202568.7%-12.4%-7.0%
202481.9%2.6%5.5%
202379.5%-30.9%-26.1%
202276.6%-53.2%-49.0%
202183.2%-42.6%-33.3%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Castle Biosciences, Inc. (CSTL) Earnings Overview

As of May 8, 2026, Castle Biosciences, Inc. (CSTL) reported trailing twelve-month net income of -$13M, reflecting -233.9% year-over-year growth. The company earned $-0.43 per diluted share over the past four quarters, with a net profit margin of -7.0%.

Looking at the long-term picture, CSTL's historical earnings data spans multiple years. The company achieved its highest annual net income of $18M in fiscal 2024.

Castle Biosciences, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including NTRA (-$208M net income, -9.0% margin), EXAS (-$208M net income, -6.4% margin), VCYT ($88M net income, 12.8% margin), CSTL has outperformed on profitability metrics. Compare CSTL vs NTRA →

CSTL Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
CSTL logoCSTLCurrent
-$13M$-0.43-7.0%-5.2%-233.9%—
NTRA logoNTRA
-$208M$-1.52-9.0%-14.3%+0.7%
EXAS logoEXAS
-$208M$-1.10-6.4%-8.7%+80.3%
VCYT logoVCYT
$88M$1.0812.8%5.3%+164.5%
ARDX logoARDX
-$58M$-0.24-15.1%-36.2%-52.9%
FLGT logoFLGT
-$61M$-1.97-18.8%-5.4%-39.7%
Best in group
Lowest in group

CSTL Historical Earnings Data (2017–2025)

9 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$24M-232.4%-$43M$-0.83-7.0%-12.4%
2024$18M+131.7%$9M$0.625.5%2.6%
2023-$57M+14.4%-$68M$-2.14-26.1%-30.9%
2022-$67M-114.6%-$73M$-2.58-49.0%-53.2%
2021-$31M-204.3%-$40M$-1.24-33.3%-42.6%
2020-$10M-294.9%-$7M$-0.54-16.4%-10.4%
2019$5M+182.9%$7M$-0.2110.2%14.1%
2018-$6M+48.5%-$4M$-0.60-27.9%-16.8%
2017-$12M--$11M$-1.26-89.9%-79.2%

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Compare CSTL vs DBVT

Side-by-side business, growth, and profitability comparison vs DBV Technologies S.A..

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CSTL — Frequently Asked Questions

Quick answers to the most common questions about buying CSTL stock.

Is CSTL growing earnings?

CSTL EPS fell to $-0.43, with earnings declining -233.9%. This contrasts with the 5-year CAGR of N/A. TTM net income dropped to $-13M.

What are CSTL's profit margins?

Castle Biosciences, Inc. net margin is -7.0%, with operating margin at -12.4%. Below-average margins reflect competitive or cost pressures.

How consistent are CSTL's earnings?

CSTL earnings data spans 2017-2025. The declining earnings trend is -233.9% YoY. Historical data enables comparison across business cycles.

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CSTL Earnings Over Time (2017–2025)

Net income and EPS trends