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Enanta Pharmaceuticals, Inc. (ENTA) Total Return Calculator with Dividends Reinvested

Enanta Pharmaceuticals, Inc.

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The total return for Enanta Pharmaceuticals, Inc. (ENTA) stock is +201.78% over the past 12 months. So far it's up 5.69% this year. The 5-year total return is -70.12%, meaning $10,000 invested in ENTA stock 5 years ago would be worth $2,988 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in ENTA 1 year ago, it would be worth $30,119 today — you'd have gained $20,119.

With Dividends Reinvested$30,119+201.19%

Price Only (No DRIP)$30,119+201.19%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in ENTA

1Y$30,178+$20,178 (+201.8%)201.8% CAGR

3Y$4,439-$5,561 (-55.6%)-23.7% CAGR

5Y$2,988-$7,012 (-70.1%)-21.5% CAGR

10Y$6,103-$3,897 (-39.0%)-4.8% CAGR

15Y$8,871-$1,129 (-11.3%)-0.8% CAGR

20Y$8,871-$1,129 (-11.3%)-0.6% CAGR

30Y$8,871-$1,129 (-11.3%)-0.4% CAGR

Enanta Pharmaceuticals, Inc. did not pay dividends during this period. Total return = price return.

Loading ENTA total return...

As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	+5.69%	—	+5.69%	—	$10,569
1Y	+201.78%	201.78%	+201.78%	—	$30,178
3Y	-55.61%	-23.72%	-55.61%	—	$4,439
5Y	-70.12%	-21.46%	-70.12%	—	$2,988
10Y	-38.97%	-4.82%	-38.97%	—	$6,103
15Y	-11.29%	-0.80%	-11.29%	—	$8,871
20Y	-11.29%	-0.60%	-11.29%	—	$8,871
30Y	-11.29%	-0.40%	-11.29%	—	$8,871

Risk & Highlights

Best Year+182.11%2025

Worst Year-79.43%2023

Max Drawdown-31.86%2025-09-29 → 2025-10-02 · Recovered 2025-12-19

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-0.83%	-0.83%	—	+0.41%	-1.2pp
2025	+182.11%	+182.11%	—	+16.64%	+165.5pp
2024	-42.96%	-42.96%	—	+24.00%	-67.0pp
2023	-79.43%	-79.43%	—	+24.81%	-104.2pp
2022	-37.23%	-37.23%	—	-19.95%	-17.3pp

ENTA outperformed the S&P 500 by 170.46pp over the past year (+201.78% vs +31.32%).

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ENTA Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
ENTAEnanta Pharmaceuticals, Inc.	$442M	+15.0%	+5.7%	+201.8%	—	-55.6%	-70.1%	-39.0%
ACHVAchieve Life Sciences, Inc.	$253M	+48.6%	-3.4%	+93.5%	—	-45.1%	-50.9%	-99.8%
AGIOAgios Pharmaceuticals, Inc.	$1.6B	-22.5%	-0.7%	-4.7%	—	+6.2%	-51.0%	-38.1%
ARQTArcutis Biotherapeutics, Inc.	$3.0B	+2.2%	-16.7%	+68.8%	—	+69.5%	-25.9%	+10.9%
PRTAProthena Corporation plc	$602M	+11.4%	+21.5%	+52.1%	—	-85.5%	-52.7%	-70.8%
FOLDAmicus Therapeutics, Inc.	$4.5B	+0.3%	+1.5%	+134.1%	—	+19.0%	+50.9%	+125.0%
RCUSArcus Biosciences, Inc.	$2.6B	+16.9%	+11.6%	+220.2%	—	+31.0%	-13.7%	+52.9%
IMVTImmunovant, Inc.	$5.8B	+15.2%	+10.7%	+107.2%	—	+48.4%	+73.9%	+188.1%
ALNYAlnylam Pharmaceuticals, Inc.	$40.4B	-8.3%	-24.3%	+12.3%	—	+44.3%	+129.4%	+445.5%
VRTXVertex Pharmaceuticals Incorporated	$108.8B	-1.5%	-5.4%	-5.0%	—	+24.3%	+100.6%	+399.9%
GILDGilead Sciences, Inc.	$169.8B	-2.7%	+12.8%	+42.5%	+3.3pp	+85.3%	+127.5%	+92.6%

Compare:ENTA vs ACHV ENTA vs AGIO ENTA vs ARQT ENTA vs ACHV vs AGIO

About ENTA Dividend Returns

Enanta Pharmaceuticals, Inc. (ENTA) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of ENTA over the past year?

Enanta Pharmaceuticals, Inc. (ENTA) delivered a return of 201.78% over the past year. Since ENTA does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in ENTA be worth today?

A $10,000 investment in Enanta Pharmaceuticals, Inc. one year ago would be worth $30,178 today, representing a gain of $20,178.

Q3Does ENTA pay dividends?

Enanta Pharmaceuticals, Inc. (ENTA) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For ENTA, the total return equals the price-only return.

Q4Did ENTA beat the S&P 500?

Yes, Enanta Pharmaceuticals, Inc. (ENTA) outperformed the S&P 500 by 170.46 percentage points over the past year. ENTA delivered a total return of 201.78%, compared to the S&P 500's 31.32%. This 170.46pp alpha means investors in ENTA earned more than a passive S&P 500 index fund.

Q5What is ENTA's worst drawdown?

Enanta Pharmaceuticals, Inc. (ENTA) experienced a maximum drawdown of -31.86% over the past year, declining from its peak on 2025-09-29 to its trough on 2025-10-02. The stock recovered to its prior peak by 2025-12-19. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is ENTA's long-term total return over 10, 20, or 30 years?

Here are Enanta Pharmaceuticals, Inc. (ENTA)'s long-term returns with dividends reinvested. Over 10 years, the total return is -39.0% (-4.8% CAGR) — $10,000 would have grown to $6,103. Over 20 years: -11.3% total return (-0.6% CAGR) — $10,000 → $8,871. Over 30 years: -11.3% total return (-0.4% CAGR) — $10,000 → $8,871. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was ENTA's best and worst year?

Enanta Pharmaceuticals, Inc.'s best calendar year was 2025 with a total return of 182.1%. Its worst year was 2023 with a total return of -79.4%. This range shows the volatility investors should expect — the difference between the best and worst year is 261.5 percentage points.