Sera Prognostics, Inc. (SERA) Total Return Calculator with Dividends Reinvested

Sera Prognostics, Inc.

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The total return for Sera Prognostics, Inc. (SERA) stock is -9.11% over the past 12 months. So far it's down 38.50% this year. The 5-year total return is -84.50%, meaning $10,000 invested in SERA stock 5 years ago would be worth $1,550 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in SERA 1 year ago, it would be worth $9,225 today — you'd have lost $775.

With Dividends Reinvested$9,225-7.75%

Price Only (No DRIP)$9,225-7.75%

Period2025-06-25 → 2026-06-24

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in SERA

1Y$9,089-$911 (-9.1%)-9.1% CAGR

3Y$5,013-$4,987 (-49.9%)-20.6% CAGR

5Y$1,550-$8,450 (-84.5%)-31.1% CAGR

10Y$1,550-$8,450 (-84.5%)-17.0% CAGR

15Y$1,550-$8,450 (-84.5%)-11.7% CAGR

20Y$1,550-$8,450 (-84.5%)-8.9% CAGR

30Y$1,550-$8,450 (-84.5%)-6.0% CAGR

Sera Prognostics, Inc. did not pay dividends during this period. Total return = price return.

Loading SERA total return...

As of 2026-06-25

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-38.50%	—	-38.50%	—	$6,150
1Y	-9.11%	-9.11%	-9.11%	—	$9,089
3Y	-49.87%	-20.56%	-49.87%	—	$5,013
5Y	-84.50%	-31.12%	-84.50%	—	$1,550
10Y	-84.50%	-17.01%	-84.50%	—	$1,550
15Y	-84.50%	-11.69%	-84.50%	—	$1,550
20Y	-84.50%	-8.90%	-84.50%	—	$1,550
30Y	-84.50%	-6.02%	-84.50%	—	$1,550

Risk & Highlights

Best Year+356.49%2023

Worst Year-83.57%2022

Max Drawdown-61.12%2025-06-27 → 2026-05-13

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-23.67%	-23.67%	—	+0.41%	-24.1pp
2025	-64.59%	-64.59%	—	+16.64%	-81.2pp
2024	+36.35%	+36.35%	—	+24.00%	+12.3pp
2023	+356.49%	+356.49%	—	+24.81%	+331.7pp
2022	-83.57%	-83.57%	—	-19.95%	-63.6pp

SERA underperformed the S&P 500 by 29.95pp over the past year (-9.11% vs +20.84%).

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SERA Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
SERASera Prognostics, Inc.	$70M	-12.1%	-38.5%	-9.1%	—	-49.9%	-84.5%	-84.5%
NTRANatera, Inc.	$37.2B	+29.4%	+13.6%	+51.3%	—	+421.5%	+117.1%	+1830.0%
PGNYProgyny, Inc.	$2.1B	+7.3%	+4.5%	+26.5%	—	-27.7%	-54.7%	+68.7%
OVIDOvid Therapeutics Inc.	$330M	+2.0%	+42.0%	+728.6%	—	-26.7%	-41.7%	-79.6%
INVAInnoviva, Inc.	$1.7B	+4.2%	+19.0%	+14.3%	—	+87.0%	+75.6%	+129.1%
ILMNIllumina, Inc.	$26.6B	+20.6%	+30.3%	+91.3%	—	-6.1%	-61.5%	+29.7%
EXASExact Sciences Corporation	$20.0B	—	+3.1%	+105.0%	—	+11.9%	-18.4%	+809.1%
CSTLCastle Biosciences, Inc.	$671M	+12.3%	-42.6%	+15.4%	—	+72.7%	-70.5%	+3.4%
LHLabcorp Holdings Inc.	$21.8B	+2.6%	+5.9%	+2.1%	+1.1pp	+35.0%	+21.6%	+148.7%
DGXQuest Diagnostics Incorporated	$22.5B	+5.3%	+17.8%	+14.7%	+1.8pp	+50.2%	+68.4%	+188.4%
TMOThermo Fisher Scientific Inc.	$182.9B	+9.8%	-16.8%	+22.2%	+0.4pp	-4.8%	+0.8%	+246.3%

Compare:SERA vs NTRA SERA vs PGNY SERA vs OVID SERA vs NTRA vs PGNY

About SERA Dividend Returns

Sera Prognostics, Inc. (SERA) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of SERA over the past year?

Sera Prognostics, Inc. (SERA) delivered a return of -9.11% over the past year. Since SERA does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in SERA be worth today?

A $10,000 investment in Sera Prognostics, Inc. one year ago would be worth $9,089 today, representing a loss of $911.

Q3Does SERA pay dividends?

Sera Prognostics, Inc. (SERA) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For SERA, the total return equals the price-only return.

Q4Did SERA beat the S&P 500?

No, Sera Prognostics, Inc. (SERA) underperformed the S&P 500 by 29.95 percentage points over the past year. SERA delivered a total return of -9.11%, compared to the S&P 500's 20.84%. This means a passive S&P 500 index fund outperformed SERA by 29.95pp during this period.

Q5What is SERA's worst drawdown?

Sera Prognostics, Inc. (SERA) experienced a maximum drawdown of -61.12% over the past year, declining from its peak on 2025-06-27 to its trough on 2026-05-13. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is SERA's long-term total return over 10, 20, or 30 years?

Here are Sera Prognostics, Inc. (SERA)'s long-term returns with dividends reinvested. Over 10 years, the total return is -84.5% (-17.0% CAGR) — $10,000 would have grown to $1,550. Over 20 years: -84.5% total return (-8.9% CAGR) — $10,000 → $1,550. Over 30 years: -84.5% total return (-6.0% CAGR) — $10,000 → $1,550. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was SERA's best and worst year?

Sera Prognostics, Inc.'s best calendar year was 2023 with a total return of 356.5%. Its worst year was 2022 with a total return of -83.6%. This range shows the volatility investors should expect — the difference between the best and worst year is 440.1 percentage points.

How much would $100/month in SERA be worth today?

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