Annexon, Inc. (ANNX)
Valuation Overview•Is Annexon, Inc. Overvalued or Undervalued?
The market is pricing the stock in line with historical averages, assuming steady-state growth.
Fragile underlying quality score of 25/100; weak margins or elevated debt leverage warrant caution.
Analysts remain bullish, forecasting further upside expansion with consensus targets suggesting solid gains.
Verdict: Mixed fundamental profile with offsetting strengths and weaknesses.
Wall Street is highly bullish, projecting significant upside with steady expected earnings growth. However, capital return yields remain modest, anchored by a strong, well-covered dividend yield.
ANNX struggles with subpar profitability and pressured margins. This is backed by a fortress balance sheet, holding significant net cash ($136M) and minimal debt risk.
The company maintains stable top-line performance paired with stable bottom-line earnings.
| Financial Metric | Trend (12Q) | Latest Qtr | 1Y Growth | 3Y CAGR | 5Y CAGR | 10Y CAGR |
|---|---|---|---|---|---|---|
| Revenue | $0.00 | — | — | — | — | |
| EBITDA | -$45.1M | — | -14.2% | — | — | |
| Net Income | -$44.1M | -49.6% | -13.3% | — | — | |
| EPS (Diluted) | $-0.23 | -32.7% | — | — | — | |
| Free Cash Flow | -$46.8M | -58.0% | -14.9% | -28.3% | — |
| Metric | TTM | 3Y Avg | 5Y Avg | 10Y Avg |
|---|---|---|---|---|
| Gross Margin | — | — | — | — |
| Operating Margin | — | — | — | — |
| Net Margin | — | — | — | — |
| FCF Margin | — | — | — | — |
| Quarter | EPS Est. | EPS Act. | Surprise | EPS | Rev |
|---|---|---|---|---|---|
| Q2'26Latest | $-0.30 | $-0.23 | +23.3% | ||
| Q1'26 | $-0.32 | $-0.28 | +12.5% | ||
| Q4'25 | $-0.34 | $-0.37 | -8.8% | ||
| Q3'25 | $-0.36 | $-0.34 | +5.6% | ||
| Q2'25 | $-0.30 | $-0.37 | -23.3% | ||
| Q1'25 | $-0.28 | $-0.33 | -17.9% | ||
| Q4'24 | $-0.26 | $-0.25 | +3.8% | ||
| Q3'24 | $-0.23 | $-0.23 | +0.0% |
Total return is +116.3% (1Y), outperforming the benchmark by +95.5%
| Period | Total Return | vs S&P 500 (Alpha) | Dividend Contribution |
|---|---|---|---|
| YTD | +13.0% | +5.7% | — |
| 1Y | +116.3% | +95.5% | — |
| 3YCAGR | +16.5% | -4.4% | — |
| 5YCAGR | -25.9% | -37.6% | — |
| 10YCAGR | -11.4% | -25.1% | — |
The S&P 500 is at 30.6x trailing P/E — Expensive relative to historical averages.
Quick answers to common questions about Annexon, Inc. (ANNX) valuation, health, and returns.
Annexon, Inc. valuation is being assessed using available models.
Annexon, Inc. has multiple valuation anchors: Wall Street Analyst Target: $7.00 (implying +27.7% upside). A convergence of these signals offers higher conviction.
Annexon, Inc. displays weak financial health with a composite quality score of 25/100, supported by a Altman Z-Score of 3.2 (safe zone), Piotroski F-Score of 1/9, Return on Invested Capital (ROIC) of -93.2%.
Annexon, Inc. pays a 0.2% dividend yield, covered by a 0% payout ratio with 0 years of growth, supplemented by a 0.0% buyback yield.
Annexon, Inc.'s current growth trajectory is Stable. The company achieved N/A 1Y revenue growth and -32.7% 1Y EPS growth, compared to its 3Y revenue CAGR of N/A.
Wall Street consensus is Buy based on 10 analysts, beating EPS expectations in 67% of recent quarters with a 2-quarter streak. The consensus price target represents a +27.7% change from current levels.
Investment risks for Annexon, Inc. include: -35.1% 1-year max drawdown, high beta (1.78x market volatility). Volatility risk is characterized by a beta of 1.78x.
No. These computations are purely quantitative model outputs for informational purposes. They do not account for qualitative management shifts or macro events. Always consult a licensed RIA before buying or selling shares.
Disclaimer: This page is for informational purposes only and does not constitute financial advice. All valuation models, scores, and target estimates are automated computations under stated assumptions and should not be relied upon as the sole basis for any investment decision.